ANXIETY

This study aims to improve access to effective therapy for children with anxiety and OCD by testing different delivery methods. It will compare weekly Cognitive Behavioral Therapy (CBT) delivered entirely in-person, entirely via telehealth video calls, or through a flexible mix o…

This study is observing how esketamine nasal spray works for people with severe, treatment-resistant depression in real-world clinics. It aims to see who benefits most from the treatment and how it affects their daily life, work, and social functioning. Researchers will also look…

This study is testing a new system to match community college students with anxiety or depression to the right level of mental health care. It will compare a standard method based on symptoms to a more personalized method that also considers life stress, background, and other fac…

This study tests an online platform called MOVIN that helps pregnant and postpartum people manage depression and anxiety. It connects participants with a care coordinator to create personalized treatment plans, working with their regular doctor and a specialist psychiatrist if ne…

This study is testing if a once-daily capsule called centanafadine can help control symptoms in adults who have both Attention-Deficit/Hyperactivity Disorder (ADHD) and anxiety. Over 300 participants will take either the drug or a placebo for 8 weeks to see which is more effectiv…

This study tests a new approach where teachers in rural Indian schools are trained to provide mental health support to teenagers. The goal is to see if this teacher-led system is practical, acceptable to students and families, and can help improve symptoms of depression and anxie…

This study is testing whether helping with both depression and poverty works better than treating depression alone for low-income women in rural Bangladesh. It will compare two groups: one gets depression treatment plus poverty aid, and the other gets only depression treatment. R…

This study is testing an online, 9-week family program designed to help parents and caregivers of LGBTQ+ youth of color become more supportive and accepting. The goal is to see if improving family relationships can reduce the youth's depression, anxiety, and other health risks li…

This UCLA study is testing a personalized, non-invasive brain stimulation treatment for people who still have symptoms like headaches, dizziness, fatigue, and brain fog months after a concussion. Researchers will use MRI scans to map each person's brain and then apply magnetic pu…

This study is testing a flexible therapy approach called FIRST that teaches children and teens skills to manage difficult emotions like anxiety, sadness, and anger. Researchers will compare FIRST to standard therapy for 212 youth ages 7-15 who are struggling with mental health ch…

This study is evaluating a telephone support program called SUSTAIN, designed to help manage depression, anxiety, and chronic pain in older adults. The program provides check-in calls, education, and care coordination for 4,000 seniors in Pennsylvania. Researchers want to see how…

This study is testing a special mobile app designed for Black pregnant women. The app provides culturally relevant tools to build self-advocacy skills, improve communication with doctors, and create a support network. Researchers want to see if using the app can help reduce depre…

This study tests a new support program for low-income patients with chronic diseases like diabetes and heart problems after they leave the hospital. It provides free medications, delivers them to the bedside and then to the home, and offers a coach to help with follow-up care. Re…

This study is testing whether a computer-based brain training program can help people in forensic mental health care. The training aims to improve thinking skills like planning and problem-solving, which are often impaired. Researchers hope better thinking skills will lead to few…

This study is testing whether a simple daily breathing exercise can help reduce dementia risk in older adults. Researchers will compare a high-resistance breathing training to a low-resistance version over 8 weeks. They'll measure effects on blood pressure, thinking skills, mood,…

This study is testing how well two common therapy techniques work when used together for anxiety and depression. Researchers want to see if combining 'cognitive restructuring' (changing unhelpful thoughts) with 'detached mindfulness' (observing thoughts without judgment) is more …

This study is testing a new support program for young people (ages 15-21) living with HIV in Zambia. The program combines peer mentoring with mental health skills training to help them cope with the shame and stress related to HIV, violence, and depression. Researchers want to se…

This study is testing whether adding a brief online therapy for fear of the unknown makes standard firearm safety counseling more effective for military members. It aims to see if reducing this specific anxiety helps people feel safer storing their firearms locked and unloaded, w…

This study is testing whether a simple breathing exercise program can help young adults from minority backgrounds reduce stress and lower their risk of heart disease. Participants with a family history of heart problems will practice guided breathing techniques for four weeks whi…

This study is testing whether an online parenting program can improve family wellness and help prevent mental health issues in children. Researchers are enrolling 500 Filipino families in California, where half will take the online parenting course and half will receive standard …

This study is testing a new online training method for mentors in rural communities. The goal is to help mentors learn how to deliver a proven program that prevents depression and anxiety in teenagers. Researchers will compare this new 'just-in-time' training to usual training me…

This study is testing whether a fun, game-like virtual reality (VR) program can help children and teenagers learn to better manage their emotions. Researchers want to see if this training can prevent anxiety and depression. About 160 kids aged 10-16 will use the VR games for five…

This study is testing two different school-based programs designed to help teenagers get better sleep. It involves 3,000 students aged 13-19 in Sweden. The goal is to see if improving sleep can prevent future symptoms of depression and anxiety while also boosting school performan…

This study tests a family program designed to prevent multiple health problems common in Latino immigrant families. The six-session program, led by community health workers, helps families manage stress, build resilience, and access community resources. Researchers want to see if…

This small early study is testing whether oral ketamine (a medication sometimes used for depression) can help reduce anxiety in people with pancreatic cancer. Twenty participants will try both ketamine and a placebo pill in random order to see if it's safe and tolerable. The main…

This study is testing whether a smartphone app called JoyPop can help young adults (ages 18-25) manage difficult emotions, stress, anxiety, and depression while they are on a waitlist for professional mental health services. Researchers in Northwestern Ontario will compare the ap…

This study is testing if a simple breathing exercise can help people feel less anxious, in less pain, and less nauseous when they undergo an ERCP, a common but uncomfortable medical procedure. About 70 adult patients will be randomly assigned to either learn the 'box breathing' t…

This study is testing if showing children a simple animated video of a medical procedure can make it less scary and painful. It focuses on kids aged 4 to 12 who need to have temporary pins removed after surgery for a broken elbow. Researchers will compare pain and anxiety levels …

This study is testing whether using virtual reality (VR) can help patients feel less anxious before heart surgery, so they might not need as much anxiety medication. It will involve 40 adults who are scheduled for elective surgery and who have already asked for medication to calm…

This study is testing an online group support program designed to help adults with spina bifida. Over 10 weekly video sessions, participants will work on improving their self-esteem, social skills, and overall psychological well-being. The goal is to see if this accessible, remot…

This study is testing whether psilocybin (a compound found in 'magic mushrooms'), combined with psychotherapy, can help reduce depression and anxiety in people who have survived cancer. It will involve about 20 participants and aims to check if the treatment is safe and practical…

This study is testing whether a new group therapy method called 'I-Reconstruction' can help reduce anxiety in adults. Researchers will compare people who attend 10 weekly online therapy sessions with a group receiving usual care to see if the new approach is more effective. The m…

This study is testing whether online group cognitive behavioral therapy can help improve mental health for people with cystic fibrosis and their caregivers. It will compare this specific therapy to general online support groups over 13 weekly sessions. The goal is to see which ap…

This study is testing whether a specific type of music therapy, where students write songs, can help reduce feelings of depression, anxiety, and stress while improving social connections. Researchers will compare songwriting sessions to simple music listening and discussion in 20…

This study is testing whether a fun, game-like music training program can help children from low-income families cope better with stress. 174 children aged 8 to 12 who are at risk for anxiety or depression will be randomly assigned to either take weekly music lessons or participa…

This early-stage study is testing whether a new AI chatbot, called Therabot-CALM, is easy to use and acceptable for people who have cannabis use disorder along with anxiety or depression. The main goal is to see if people find the app helpful and user-friendly, not to prove it tr…

This study is testing whether watching a short, animated video about what happens during a nail biopsy can help patients feel less anxious and more informed before their procedure. Researchers will enroll 30 adults who have been recommended for a nail biopsy and randomly assign s…

This study is testing whether psilocybin-assisted therapy can help adult children of genocide survivors who struggle with depression and anxiety. Researchers will give 100 participants two doses of psilocybin alongside therapy sessions to see if it reduces symptoms and improves r…

This study aims to see if combining talk therapy (CBT) with light therapy, medication, or melatonin can help improve sleep quality, fatigue, anxiety, and depression in people with advanced cancer. Researchers will compare these active treatments against placebo (inactive) treatme…

This study is testing whether a nutritional drink called 'Think Tank' can help improve mental sharpness and well-being after someone experiences stress. Researchers will recruit 40 healthy women aged 40-60 to see if the drink helps with memory, focus, and mood better than a place…

This small pilot study is testing whether a specific breathing meditation program called SKY can help reduce stress and anxiety in college students. 56 students will be randomly assigned to either the SKY program (which includes a retreat and weekly sessions) or a general online …

This study is testing whether a new program called FRAME helps people with heart failure talk about and get support for mental health issues like stress, anxiety, and depression. About 7,300 patients at clinics in Ontario, Canada, will use the FRAME tool and answer surveys before…

This study is testing if a brief writing exercise can help reduce symptoms of depression and anxiety in LGBTQ+ veterans. The therapy involves three sessions where participants write about stressful experiences related to their sexual identity. Researchers want to see if this simp…

This study tests whether a team-based care program can improve emotional well-being for adults with epilepsy who also experience anxiety or depression. Researchers will compare the new program against standard neurology care in 60 participants over 24 weeks. The program involves …

This study is testing whether a phone app and monthly coaching calls can help firefighters get better sleep. Fifty firefighters will try the app for three months, tracking sleep and learning healthy habits, while others receive basic sleep information. The main goal is to see if …

This study is testing whether a structured breathing practice is a practical and acceptable way to help teenagers with anxiety and depression. It involves 40 teens, ages 12-17, from both rural and non-rural areas. The main goal is to see if the breathing program is easy to use an…

This study is testing whether an 8-week online mindfulness program can help reduce the severe fatigue often experienced by people with sarcoidosis. It will also see if the program improves symptoms of anxiety and depression. Researchers will compare the mindfulness group to a mon…

This study is testing whether listening to low-intensity, soothing music can help reduce anxiety in teenagers and young adults. Researchers will measure changes in anxiety symptoms, brain blood flow, and heart rate patterns in 60 participants aged 18-25. The goal is to see if thi…

This UCLA study is testing whether looking at pictures of supportive people can help reduce fear in adults with social anxiety. Researchers will compare how 100 participants (50 with social anxiety, 50 without) respond to fearful cues when paired with either a photo of someone th…

This study is testing a type of talk therapy to see if it helps improve mental health for men who are HIV-positive. It will involve 24 participants and focuses on reducing symptoms of stress, anxiety, and depression. The goal is to see if this therapy is practical and effective f…

This study is testing whether a smartphone app called Safe Haven can help reduce depression, anxiety, and stress in college students. Researchers will compare students using the app alongside regular campus mental health services to students receiving only standard campus care. T…

This study is testing two different phone-delivered support programs to see which one better helps women recover after abdominal surgery for suspected gynecologic cancer. It will compare a mindful movement and breathing program against a life reflection program. The goal is to se…

This study is testing if a short, guided breathing exercise called 'cardiac coherence' can help reduce anxiety for people who feel nervous about getting an MRI scan. The researchers will enroll 60 adults who report high anxiety about their upcoming upper-body MRI. They will measu…

This study is testing whether mindfulness meditation can help first-generation college students who experience anxiety or depression. Researchers will compare a 4-week mindfulness program to an educational program to see which better improves students' well-being and their intent…

This study is testing whether using the Calm meditation app for 10 minutes a day can help people with blood cancers who have trouble sleeping. Researchers will enroll 276 patients to see if the app improves sleep quality, reduces fatigue and anxiety, and lowers body inflammation …

This study is testing if a music therapy app on a tablet can reduce anxiety as effectively as a calming gas (EMONO) for patients getting painful, scan-guided injections for low back pain. Researchers want to see if this simple, non-invasive method is a good alternative to the gas…

This study is testing whether a specific probiotic (Clostridium butyricum) can help reduce feelings of anxiety and depression in people who have functional dyspepsia, a common condition causing ongoing stomach pain or discomfort. The trial will involve 180 adults who will take ei…

This study is testing whether a guided smartphone app therapy program can help reduce depression and anxiety symptoms in high school students. Researchers will compare the app-based program to the usual school mental health services. The goal is to see if this digital tool is a p…

This study is testing whether a free, 5-week online stress-management program from the World Health Organization (WHO) can improve mental health for employees at small and medium-sized companies in the Netherlands. Researchers will compare two groups: one that gets the program pl…

This study is testing if a special, calming way of talking to patients can reduce their emotional distress during a common heart test called coronary angiography. 306 adults scheduled for this elective procedure will be randomly assigned to either receive this 'hypnotic communica…

This pilot study is testing two different outreach methods to help more lung cancer patients access mental health support through telehealth. Researchers want to see if more personalized outreach leads to more patients starting and continuing with care for anxiety and depression.…

This study is testing whether a special group therapy program can help university students in Turkey manage anxiety. The program is based on Cognitive Behavioral Therapy (CBT) but is adapted to fit Turkish culture and student life. About 40 students from Bogazici University will …

This study is testing whether watching virtual reality (VR) videos can help reduce anxiety and improve the overall experience for people receiving radiation therapy for cancer. Researchers will compare different VR experiences against a standard educational video to see which wor…

This study is testing whether using a virtual reality (VR) headset before surgery can help reduce patients' anxiety. About 172 adults scheduled for elective surgery will be randomly assigned to either use a VR headset with relaxing scenes and sounds or receive standard care. Rese…

This study is testing a mobile app called Blueprint, designed to help people manage depression, anxiety, and PTSD after surviving a serious heart or lung condition in the hospital. Researchers will enroll 400 people from four hospitals and randomly assign them to use either the B…

This study is testing if using a simple stress ball can help reduce pain and anxiety for patients having a chest tube removed after open heart surgery. It will involve 46 patients, with half using the stress ball during the procedure and half receiving only standard care. Researc…

This study is testing whether a smartphone app called JoyPop can help Indigenous young adults (ages 18-25) manage difficult emotions like stress, anxiety, and depression while they wait for formal mental health services. Researchers will compare the app's effects to usual waitlis…

This study is testing whether smelling lavender essential oil can help improve mental health and quality of life for women waiting to undergo IVF treatment. It will involve 120 women who are feeling anxious or stressed. Participants will be split into three groups: one will smell…

This study is testing whether listening to music can help patients feel less anxious during hand surgery performed while they are awake. Researchers are comparing the effect of patients listening to their own choice of music versus a standard set of relaxing music. About 170 adul…

This study is testing whether a common relaxation technique is more helpful for burn survivors when it's delivered through virtual reality (VR). Adult burn survivors with ongoing symptoms like pain, itch, or anxiety will try both a standard relaxation program and a VR-enhanced ve…

This study is testing if giving a small dose of a sedative called midazolam during the start of anesthesia helps prevent confusion and anxiety in older adults after surgery. Researchers will compare the drug to a placebo in over 600 patients aged 65-85. The main goal is to see if…

This study is testing a 9-month wellness program designed to help staff who work to prevent gun violence. The program teaches skills to manage emotions, reduce burnout, and improve mental health. It aims to see if this support helps workers feel better and stay in their jobs long…

This study is testing a 10-week online psychological treatment program for cancer survivors who are struggling with anxiety, depression, or fear of their cancer returning. It will enroll 400 survivors in Sweden to figure out which parts of the online therapy are most helpful. The…

This study is testing whether a smartphone app called JoyPop can help teenagers manage difficult emotions, stress, anxiety, and depression while they wait to start formal mental health therapy. Researchers will compare 110 teens aged 12-17 who use the app to those who receive usu…

This study is testing two simple, two-week programs to see if they can help college students who use social media a lot feel better. 300 students will try either daily mindfulness meditation, reducing social media by 30 minutes to exercise instead, or no change. Researchers will …

This study is exploring whether a therapy program for parents and young children can reduce parental stress, anxiety, and depression while improving the parent-child relationship. Researchers will enroll 80 parents of children aged 2-7 and measure stress levels, a bonding hormone…

This study is testing if an online support program can help teenagers (ages 15-18) who have just left a psychiatric hospital. The program connects teens with trained peer mentors and specialists for virtual meetings and group support over 8 weeks. Researchers want to see if this …

This study is testing if watching a short animated film and reading a storybook can help reduce fear and anxiety in children who have just been diagnosed with type 1 diabetes. It will involve 64 children aged 7 to 12. One group will watch the film and read the book, while another…

This study is testing whether a gentle skin stimulation technique can help reduce anxiety in patients scheduled for heart surgery. Researchers will compare the real technique to a sham (fake) treatment to see if it changes the body's stress response and lowers anxiety levels. The…

This study is testing a 6-part online therapy program called Emotion Regulation Therapy (ERT) for adults in New York who struggle with excessive worry, rumination, or self-criticism. The goal is to see if learning specific emotional regulation skills can reduce symptoms of anxiet…

This study is testing a program that connects pregnant women in disaster-affected areas with experienced mothers as mentors. The goal is to see if group meetings and peer support can reduce anxiety and depression during pregnancy. Researchers will recruit 240 women to participate…

This study is testing whether a specific probiotic supplement (Bacillus coagulans) can help reduce feelings of anxiety and depression in people who also have chronic stomach discomfort (functional dyspepsia). About 180 adults will take either the probiotic or a placebo (dummy pil…

This study is testing whether daily breathing exercises can help reduce anxiety and stress. Researchers will compare two breathing techniques against hypnosis and an educational audiobook over 4 weeks. They will measure changes in participants' anxiety levels, brain activity, and…

This study is testing a single, online therapy session for children and teenagers in Hong Kong who are on long waiting lists for traditional mental health treatment. The goal is to see if this brief, accessible session can help reduce symptoms of depression and anxiety while they…

This study is testing two different mind-body programs designed to help cardiac arrest survivors and their caregivers manage emotional distress like anxiety and depression. The programs involve weekly sessions that teach mindfulness and resilience skills, starting in the hospital…

This study is testing whether a combination of mindfulness and a brain training technique called neurofeedback can help reduce stress and anxiety in nursing students. It will involve 36 students from the University of Salamanca who will use these techniques over four weeks. The m…

This study aims to find out which of two common talk therapies works better for autistic adults struggling with depression or anxiety. Researchers will compare Cognitive-Behavioral Therapy (CBT) and Mindfulness-Based Therapy (MBT), both delivered online, in 300 adults from North …

This study is testing if watching a short educational video before cataract surgery can help patients feel less anxious and better understand their own care. About 118 patients will be randomly assigned to either watch the video or receive standard instructions. Researchers will …

This small pilot study is testing whether playing music for patients during common back pain injections can help them feel less anxious and experience less pain. Researchers will compare anxiety and pain scores between a group that listens to music and a group that does not. The …

This study is testing a new type of talk therapy for young adults struggling with anxiety or depression. The therapy uses virtual reality to help people explore their sense of self and is designed to be more engaging for young people. Researchers will compare this new approach to…

This study is looking at whether a medical procedure called a bilateral cervical sympathetic block (BCSB) can help reduce trauma-related symptoms in Special Operations veterans. The procedure involves injecting medication near nerves in the neck to calm the body's stress response…

This study is testing whether an online therapist-guided sleep improvement program can help reduce anxiety symptoms and improve sleep for adults with both chronic insomnia and anxiety. Researchers will compare two groups: one starting the program immediately and another starting …

This study is testing whether listening to personalized music daily can help reduce anxiety and depression in people recovering from a recent stroke. About 132 participants will be randomly assigned to either receive standard care plus four weeks of daily music listening sessions…

This study is testing whether a nasal spray containing the drug midazolam can safely and quickly reduce acute anxiety in hospitalized patients receiving palliative care. It will involve 36 patients who will receive either one of two different doses of the spray or a placebo (a sp…

This study is testing whether a culturally adapted skills training program called START NOW is better than usual care at reducing depression and anxiety in adolescent refugees. Researchers will enroll 80 young migrants in Switzerland and randomly assign them to either the new tra…

This study is comparing two ways to help children aged 5-7 feel less anxious during a dental numbing shot. One group gets the standard dentist explanation, while the other watches a short cartoon video featuring an AI-generated character explaining the process. Researchers will m…

This study is testing if a short virtual reality tour of a doctor's office can make routine check-ups less scary for young children. About 100 kids aged 3 to 5 will either watch the VR tour or go through the normal waiting process before their exam. Researchers will measure how u…

This study is testing a specially adapted self-help workbook to see if it can help reduce symptoms of anxiety and depression for people in prison. About 96 participants will work through the 8-week workbook on their own, with researchers checking in to see if it's helpful and pra…

This study is testing whether an 8-week virtual reality exercise program can help improve physical and mental health for women veterans. Researchers will compare 40 veterans who use the VR adventure games to a control group, measuring changes in activity levels, mood, stress, and…

This study is testing whether a simple phone app that sends daily reminders can help people with depression become more physically active and feel better. Researchers will compare a group using the app for four weeks to a group that does not use it. They want to see if the app in…

This study tests two ways to help people with a fear of spiders. One group does a live therapy session with a real spider, another watches a therapy session over video chat, and a third group waits. Researchers will measure changes in fear, disgust, and willingness to approach sp…

This study is testing the best way to deliver a mobile app program called PRISM, which teaches skills to manage stress and build resilience. It aims to help adolescents and young adults (ages 12-25) cope with anxiety and depression after finishing their main cancer treatment. Res…

This study is testing whether a 4-week online therapy program can help people who get anxious about MRI scans. Researchers want to see if learning anxiety management and relaxation techniques through the internet can make it easier to complete an MRI. The study will involve 60 pe…

This study aims to see if a personalized form of magnetic brain stimulation can reduce persistent negative thoughts and emotions in people with depression or anxiety. Researchers will first map each participant's unique brain patterns linked to negative feelings using an MRI scan…

This study is developing and testing a culturally adapted family support program for Lakota LGBTQ2S+ youth and their caregivers. The 8-week group program aims to reduce family rejection, improve mental health, and decrease risks like depression and substance use. Researchers are …

This study is testing if showing children an interactive film during the start of anesthesia can help reduce their anxiety. It will involve 70 children, aged 2 to 6, who are having elective surgery in Chile. Researchers will compare anxiety levels in kids who watch the film to th…

This study is testing if the relaxing activity of mandala painting can help people feel better during their first chemotherapy treatment. Researchers want to see if this simple, drug-free activity can reduce feelings of anxiety and nausea, and increase comfort for 120 patients. T…

This study is testing a two-week smartphone app program designed to help people who struggle to feel pleasure (anhedonia) and experience high stress, anxiety, or depression. Participants are randomly assigned to use an app with daily audio exercises focused on gratitude, positive…

This early-stage study from Yale University is testing whether a single dose of psilocybin, the active compound in 'magic mushrooms,' is safe and tolerable for people whose daily lives are impacted by symptoms of depression, anxiety, trauma, or addiction. The study will enroll 50…

This study is testing a new program where college students are trained to provide therapy to high schoolers in rural Pennsylvania. The goal is to see if this approach can effectively reduce symptoms of depression, anxiety, and stress in teens who often have limited access to ment…

This study is testing a short, online self-help program designed to help university students who are feeling significant distress and are behind on their coursework. The program, developed by the World Health Organization, teaches skills for managing stress and improving well-bei…

This study is testing whether using a virtual reality (VR) headset during a common kidney stone treatment can help reduce patients' pain and anxiety. Seventy-two adults scheduled for the shock wave procedure will be randomly assigned to either use VR during treatment or receive s…

This study is testing whether a virtual reality meditation app or relaxing music works better to reduce anxiety and pain during breast biopsies. Researchers will compare these two approaches against standard care in 600 women undergoing the procedure. The goal is to find non-medi…

This study is testing whether melatonin (a natural sleep hormone) or pregabalin (a prescription nerve pain medication) works better to reduce pain and anxiety after spine surgery. Researchers will give one of these pills to 105 adults having elective spine surgery and measure the…

This study is testing a special group therapy program designed to help university students who struggle with anxiety and fear of the unknown. The therapy teaches coping skills to better handle life's uncertainties. Researchers will measure changes in anxiety, worry, and emotional…

This study is testing if a simple acupressure technique can help patients feel less anxious, embarrassed, and fearful during an invasive urodynamic test, which checks how the bladder works. Researchers will compare 68 patients, where half receive acupressure on specific hand, wri…

This study is testing whether a newer type of guided self-help therapy (CAT-GSH) works as well as the standard one (CBT-GSH) for people who are returning to NHS mental health services for anxiety or depression. It involves 100 participants who will choose their preferred therapy …

This study is testing a 6-week online mindfulness program designed to help adults with chronic tinnitus. Researchers want to see if this internet-based therapy can reduce the distress, anxiety, and depression often linked to the condition. They will compare the program's effects …

This study is testing a family support program designed to help refugee families cope with stress, trauma, and mental health challenges. The program brings families together in groups led by fellow refugees to build community support and improve family relationships. Researchers …

This study is testing if a simple, press-in acupuncture treatment can help reduce anxiety in adults the day before they have ear surgery. Researchers will compare real acupuncture to a fake (sham) treatment in 32 patients to see which one better lowers anxiety levels and affects …

This study is testing a smartphone app designed to help people recover from knee or hip replacement surgery. The app uses digital therapy techniques and coach support to help patients manage anxiety, depression, and pain. Researchers want to see if using the app can help patients…

This study is testing whether listening to personalized music playlists can help adults reduce feelings of stress, anxiety, and depression. Researchers will assign 2,000 participants to either receive specially designed music or no music intervention. The goal is to see if this a…

This study is testing a group mental health program delivered by phone or video call for Canadians aged 55 and older who feel lonely, isolated, anxious, or depressed. It aims to see if this easy-to-access program improves people's ability to cope with difficult feelings and reduc…

This study is testing whether a brief hypnosis session can help anxious patients stay calmer and more still during a heart MRI scan. The goal is to see if reducing anxiety leads to clearer, more usable images, which could help doctors make faster diagnoses. Researchers will compa…

This study is testing a new 12-week group therapy program for women who have experienced interpersonal trauma (like physical or sexual abuse) and are currently having suicidal thoughts. The program combines psychological counseling with physical self-defense training, aiming to b…

This study is testing whether a simple coloring activity can help reduce pain and anxiety for adults waiting to be seen in a hospital emergency department. Researchers will give patients nature-themed or geometric coloring pages and measure changes in their self-reported pain and…

This study is testing a 6-week group therapy program for parents of children with anxiety, depression, or behavioral problems. The program teaches parents skills to better support their child's emotions and behaviors. Researchers will compare families who receive the therapy imme…

This study is testing whether using a virtual reality (VR) headset during common outpatient urology procedures can help reduce patients' pain and anxiety. It will involve 56 adults undergoing procedures like prostate biopsy, cystoscopy, or circumcision. The goal is to see if this…

This study is testing a wearable headband device that delivers gentle electrical stimulation to the brain to see if it can help reduce anxiety in veterans. Up to 40 veterans with significant anxiety will use the device at home twice daily for 8 weeks. Researchers will measure how…

This study is testing if a special computer-based program can help reduce anxiety and stress in older adults with early-stage memory loss or mild Alzheimer's disease. It also looks at whether the program helps reduce the strain on their family caregivers. Researchers will compare…

This study is testing a free, 6-week online coaching program designed to help Nova Southeastern University undergraduate students manage anxiety, depression, and stress. About 160 students will be randomly assigned to either start the program immediately or be placed on a waitlis…

This study is testing an 8-week online therapy course designed to help new and expecting parents in Saskatchewan who are struggling with anxiety or depression. The course provides educational materials and therapist support through a secure website. Researchers want to see if thi…

This study is testing whether group classes teaching 'Nonviolent Communication' skills can help parents feel less stressed, anxious, or depressed. Researchers in Hong Kong will enroll 172 parents who report these symptoms and have children in primary school. One group will attend…

This study aims to understand if making people think about their own death increases symptoms of anxiety and depression. Researchers will compare two groups: one group writes about death, while a control group writes about dental pain. The goal is to learn more about the role of …

This study aims to better understand how patients feel before elective surgery and to learn which calming methods they prefer. Researchers are anonymously surveying at least 400 adult patients at a German hospital. This is an observational study only—no treatments are being teste…

This study aims to understand how women's feelings about artificial intelligence relate to their anxiety levels and overall quality of life while they undergo infertility treatment. Researchers will survey 191 women aged 18-45 who are currently receiving fertility care. The goal …

This pilot study is testing whether adults experiencing acute mental health crises like severe anxiety, depression, or psychosis can safely receive hospital-level care at home instead of in a traditional hospital. Researchers will enroll 45 carefully screened, lower-risk patients…

This study follows 540 cancer patients for 6 months to understand how anxiety and depression change during cancer treatment. Researchers will track patients' emotional symptoms and identify factors that might predict who needs more support. The goal is to learn how to better help…

This study aims to understand how anxious thinking patterns in parents might be passed on to their children. Researchers will test whether a smartphone app that teaches parents to interpret situations in less threatening ways can change parenting behaviors and reduce anxious thin…

This study aims to understand how stress affects the way older adults plan routes and use memory during navigation. Researchers will use brain scans and virtual reality tasks to compare two groups of healthy adults aged 65-80: one exposed to a mild stress test and one not. The go…

This study aims to develop a new technology platform called CAMERA that uses multiple sensors to measure brain activity, body signals, and behavior. Researchers want to see if they can use this data to predict a person's anxiety levels and memory performance throughout the day. T…

This study aims to understand how common sexual dysfunction is in women living with multiple sclerosis (MS). Researchers will enroll 140 women with MS to complete surveys about their sexual health, fatigue, mood, and other symptoms. The goal is to identify connections between sex…

This study aims to see if a non-invasive ear device can detect specific brain wave patterns linked to anxiety. Researchers will test 42 healthy volunteers, giving some anxiety-reducing drugs and others a placebo, while measuring signals from the ear canal and scalp. The goal is t…

This study is investigating whether eating a daily mix of nuts for six months can improve mental health, reduce stress, and enhance thinking skills in young adults. It will involve 135 university students aged 18-25 who will be randomly assigned to either eat nuts or not. Researc…

This study aims to understand how a common heart procedure (stent placement) affects erectile function in men. It will compare 100 men who had the procedure after a heart attack to those who had it for stable chest pain. Researchers will track changes in sexual function, depressi…

This study is testing a mobile app called TrueBlue that aims to monitor signs of depression and anxiety in pregnant women and new mothers. For 12 weeks, 125 participants in the UK will use the app weekly, reading or speaking while it records their face and voice to generate mood …

This research study aims to understand how feeling in control and your surroundings affect pain and anxiety. Healthy participants will explore different virtual reality rooms, some where they can control a painful heat stimulus and some where they cannot. Researchers will measure…

This study is exploring whether practices inspired by an ancient tradition called Dream Yoga, combined with modern virtual reality training, can change how the brain works during sleep and wakefulness. Researchers are recruiting 70 healthy adults who recall dreams regularly to co…

This study aims to understand how supporting mothers of hospitalized infants affects family wellbeing. Researchers will connect mothers experiencing depression, anxiety, or food insecurity with helpful resources and emotional support. They want to see if this assistance improves …

This study aims to define a new concept called 'visual frailty' and create a tool to measure it. Researchers will gather information from 20 Scottish adults aged 60+ with advanced age-related macular degeneration (AMD). They will look at vision, reading ability, daily function, m…

This study aims to understand if a single, brief intervention can change how people with anxiety and depression make decisions when faced with uncertainty. Researchers will measure changes in decision-making behavior and brain activity before and after the session. The goal is to…

This study is investigating whether taking a high dose of Vitamin B6 changes brain activity in people with mild to moderate anxiety or depression. Researchers will use EEG brain scans to measure neural activity and compare results between people taking Vitamin B6 and those taking…

This study aims to understand if looking at a picture of a supportive person can help people with social anxiety disorder 'unlearn' a fear response. Researchers will compare 50 healthy adults with 50 adults diagnosed with social anxiety. Participants will learn to associate an im…

This study is testing whether a special web app that uses interactive stories and a relatable character can help Latinas with anxiety or depression take the first step to get professional help. It will compare this story-based app to a standard app with informational videos and r…

This study is observing whether a free, daily after-school program in community parks improves children's health. Researchers will analyze data from about 5,000 kids aged 6-14 who participate in the program, which includes sports, games, and nutrition lessons. The goal is to see …

This study aims to understand how problems with memory, focus, and thinking (cognitive functioning) are related to taking sick leave from work for people with depression and anxiety. Researchers will follow 200 people at risk of sick leave who are receiving a specific therapy (me…

This study aims to understand the effects of a free, park-based afterschool program on teens' health and well-being. Researchers will analyze existing data from about 1,000 participants, aged 12-17, in Miami-Dade County's 'Fit2Lead' program. The program offers academic help, spor…

This study aims to understand the health, stress levels, and wellbeing of university students and employees. Researchers will use surveys and interviews to gather information on factors like loneliness, anxiety, and substance use. The goal is to use this data to help guide and im…

This Mayo Clinic study is exploring whether teaching mindfulness and meditation techniques to mothers can help them while they pump breastmilk for their premature babies in the Neonatal Intensive Care Unit (NICU). Researchers will measure if these relaxation practices are linked …