Can a new sedative make anesthesia safer for seniors?

NCT ID NCT07746505

Recruiting now Knowledge-focused Sponsor: Second Affiliated Hospital, Zhejiang University, School of Medicine Source: ClinicalTrials.gov ↗

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This study looks at two sedative drugs, remimazolam and midazolam, used to put older adults (65+) to sleep for non-cardiac surgery. The goal is to see which one offers better heart and blood pressure stability, faster recovery, and fewer complications like confusion after surgery. Researchers will observe 1,000 patients without changing their routine care, and use statistical methods to compare the two groups fairly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: remimazolam and midazolam (two sedative drugs used for general anesthesia)
What this could lead to: If remimazolam proves safer and smoother for older patients, it could become a preferred choice for anesthesia induction, reducing complications like low blood pressure and confusion after surgery.
What could go wrong: This is an observational study, not a controlled experiment, so results may be influenced by other factors. The findings will need confirmation in randomized trials before changing practice.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGED ANXIETY GENERAL ANESTHESIA INTRAOPERATIVE HYPOTENSION

Contacts and locations

Locations

The Second Affiliated Hospital of Zhejiang University School of Medicin
RECRUITING

Hangzhou, China

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