Scientists probe the brain to unravel Suicide's mysteries
NCT ID NCT02543983
First seen Jun 26, 2026 · Last updated Jul 01, 2026 · Updated 3 times
Summary
This study aims to understand what happens in the brain when someone thinks about or attempts suicide. Researchers will use brain scans, sleep monitoring, blood tests, and questionnaires to compare four groups: people with recent suicidal thoughts or attempts, those with past suicidal thoughts, people with depression or anxiety but no suicidal history, and healthy volunteers. A small subset will also receive the drug ketamine to observe its effects on mood and brain activity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ketamine
What this could lead to
If successful, this research could reveal key biological markers linked to suicide risk, pointing toward better prevention strategies or treatments.
What could go wrong
This is an early-phase observational and interventional study with a small ketamine component. It is not designed to test a new treatment, and results may not lead to immediate clinical changes.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••