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Magic mushroom therapy targets inherited trauma

NCT ID NCT06899165

Recruiting now Symptom relief Sponsor: Rachel Yehuda Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This study tests whether psilocybin (the active ingredient in magic mushrooms) combined with therapy can help reduce depression, anxiety, and stress in adults whose parents survived genocide. One hundred participants will receive a single 25mg dose under supervision, followed by six weekly therapy sessions. The goal is to see if this approach is safe and can ease the psychological burden passed down through generations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Psilocybin (a psychedelic drug) given as a 25mg capsule, plus weekly therapy sessions
What this could lead to
If it works, this could point toward a new way to ease depression and anxiety in people carrying trauma from their parents' experiences.
What could go wrong
This is a small, early-phase trial with no placebo group, so results may not be definitive. Psychedelics can cause intense emotional experiences and temporary distress.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder Depression depressive disorder Historical Trauma Stress, Psychological

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANXIETY DEPRESSION PSYCHOLOGICAL STRESS

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • The Parsons Research Center for Psychedelic Healing

    RECRUITING

    New York, New York, 10025, United States

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