Brain zapping without surgery: new study tests temporal interference for anxiety and PTSD

NCT ID NCT07558759

Recruiting now Knowledge-focused Sponsor: Emory University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 16, 2026 · Updated 2 times

Summary

This study will test a non-invasive brain stimulation method called temporal interference (TI) in 300 healthy volunteers and people with anxiety or PTSD. TI uses two weak electrical fields to target deep brain areas linked to fear and emotion without affecting the surface of the brain. Researchers will measure changes in anxiety, mood regulation, and PTSD symptoms to understand how TI affects the brain and whether it could one day be used as a treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Temporal Interference (TI) electrical stimulation device
What this could lead to: If successful, this could point toward a new non-invasive brain stimulation method to help manage anxiety and PTSD symptoms.
What could go wrong: This is an early-stage study focused on understanding brain effects, not yet testing a proven treatment. It may not lead to a therapy, and individual results may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANXIETY PTSD

Contacts and locations

Locations

Emory University
RECRUITING

Atlanta, Georgia, 30322, United States

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