ANXIETY

This study is creating a new tool to help therapists decide how to adjust standard mental health treatments to better match the cultural values and experiences of Latine youth. The goal is to improve treatment engagement and outcomes for young people dealing with anxiety, depress…

This study aims to see if a structured 12-week program can help people build healthier long-term habits. It will enroll 120 overweight, inactive adults to test a combination of supervised exercise, Mediterranean diet education, and stress-resilience workshops. Researchers will tr…

This study is testing a new mental health program in Morocco that combines several support methods, including digital tools, therapy, and school-based help. It aims to see if this integrated approach works better than standard care at reducing symptoms of depression and anxiety. …

This study aims to roll out and test a smartphone app called CONEMO to help adults manage symptoms of depression, anxiety, and insomnia. It will involve over 12,000 people who use primary healthcare services in two Brazilian cities. The goal is to see how well this proven digital…

This study tests an online therapy program that adjusts based on how quickly participants improve. 366 adults with anxiety or depression symptoms will complete 12 self-guided modules. If someone isn't improving quickly, they may receive extra therapist support. The goal is to see…

This study aims to test a new model for connecting young people to mental health care. It involves a mobile app co-designed with youth and supported by trained peer and family navigators in schools and clinics. The goal is to see if this approach helps more teens and young adults…

This study aims to see if a virtual therapy platform designed for kids, called Teleo, helps children with anxiety or mood disorders stay more involved in their treatment compared to using standard video calls like Zoom. Researchers will measure how engaged the children are, how o…

This study aims to understand how a single dose of a drug related to psilocybin (the psychedelic compound in 'magic mushrooms') might help people with depression and anxiety. Researchers will give 40 participants either the drug or a placebo and use brain scans and questionnaires…

This study is testing an online program for Michigan students aged 8-18 and their parents. The program teaches kids skills to manage physical pain, stress, anxiety, and mood. For teens 12 and older, it also includes lessons to help prevent substance use. Researchers want to see i…

This study is testing if a set of special audiobooks can teach kindergarteners skills to manage anxiety and tough emotions. It will involve 56 children in Singapore and their parents. Researchers want to see if listening to these stories is a practical and helpful way to build em…

This study is testing a smartphone app designed to prevent anxiety and depression in adults who don't currently have these conditions. Researchers will enroll about 2,600 people in Spain and Chile to try one of two versions of the app, which offers personalized plans based on ris…

This study is testing whether a virtual reality (VR) game that combines music and movement can help young adults feel less depressed and anxious and more socially connected. Researchers will compare three groups: one playing a social VR game with others, one playing a solo VR gam…

This study aims to see if simple psychology and music-based techniques can help reduce anxiety and improve overall wellbeing in middle and high school students who are in choir. Researchers will teach students specific breathing exercises, performance anxiety coping strategies, a…

This study is testing a pilot program that coaches young adult cancer survivors on how to communicate better with their friends and peers. The goal is to see if improving these conversations can help reduce feelings of anxiety, depression, and social isolation after cancer treatm…

This study is testing whether two types of breathing exercises can help patients feel better after breast cancer surgery. Researchers will compare pranayama (alternate nostril breathing) and pursed-lip breathing against standard care to see if they reduce pain and anxiety. The go…

This study tests whether increasing nurse visits from twice to four times daily, combined with structured calming conversations and simple relaxation exercises, can reduce anxiety in hospitalized patients waiting for therapeutic gastrointestinal endoscopy procedures. Researchers …

This study is testing whether listening to music can help reduce anxiety and physical stress in people having outpatient surgery for the first time. Researchers will compare the effects of patients choosing their own music versus listening to standard classical music. They will m…

This study is testing whether reading a personal narrative book helps women of childbearing age better manage their emotions, anxiety, and fears before having a hysterectomy. Researchers will compare the usual pre-surgery information and support to the same care plus the storyboo…

This study aims to see if watching a simple hourglass can help children feel less pain, fear, and anxiety during a routine blood draw. Researchers will compare two types of hourglasses—one with sand and one with colorful liquid gel—to see which works better as a distraction. The …

This study aims to see if a peer support program is helpful and practical for improving mental health in people receiving hormone care. It will enroll 100 adults in Michigan who are starting or receiving hormone treatment and report mild depression or anxiety. Participants will b…

This study will test whether watching virtual reality forest scenes can help patients feel better before and after weight-loss surgery. Researchers will measure if this relaxing experience reduces pain, anxiety, fear, and stress hormones in 70 patients. The goal is to see if this…

This pilot study is testing whether using virtual reality (VR) or a combination of VR and hypnosis can help reduce pain and anxiety for women undergoing a diagnostic hysteroscopy. The study will compare these non-drug approaches to standard care in 45 participants. The main goals…

This study is testing whether a brief aromatherapy session can help reduce stress and anxiety in emergency department patients. Researchers want to see if smelling lavender for about 5 minutes is practical and acceptable in a busy hospital setting. The study will involve 60 emerg…

This study is testing if simple, drug-free methods can make it easier for patients when a chest tube is removed after surgery. Researchers will compare whether using a gentle vibrating device or doing guided breathing exercises right before the procedure helps reduce pain and anx…

This study aims to see if a short, guided digital art program on a tablet can help children feel less anxious and stressed while they are in the pediatric intensive care unit (PICU). It will involve 60 children aged 7 to 12 who are awake and stable. Researchers will compare child…

This study is testing whether a simple text message program can help people with high levels of worry and anxiety. It will compare two approaches: one group gets daily text reminders to reduce their worry-related habits, while another group watches weekly relaxation videos. The g…

This study aims to see if listening to music or using virtual reality can help reduce pain, anxiety, and fear for children with leukemia during painful mouth care procedures. It will involve 45 children aged 6-12 who are receiving treatment. Researchers will compare these distrac…

This study is testing whether listening to music can help people with long-term pain feel less anxious and experience less pain when they undergo a specific pain treatment procedure. About 110 adults scheduled for these procedures will be randomly assigned to either listen to the…

This study is testing whether using a virtual reality (VR) headset during labor can help reduce pain and anxiety and improve the overall birth experience. About 92 women in labor will be randomly assigned to either use a VR headset showing calming nature scenes with music or rece…

This study is testing whether writing about future scenarios can help reduce social anxiety symptoms. Researchers will recruit 270 people with elevated social anxiety online and randomly assign them to write about worst-case, neutral, or best-case future scenarios. Participants w…

This study is testing whether a gentle hand massage technique called reflexology can help reduce the severe fatigue and anxiety often experienced by patients undergoing regular dialysis treatment. Researchers will compare 104 adult dialysis patients who receive eight short massag…

This study is testing a smartphone app called the Living Well Program, which provides mental health support and phone coaching. It aims to see if using the app can reduce anxiety and depression in breast cancer patients and, as a result, lower their overall healthcare costs. The …

This study will test if a special mindfulness program delivered by nurses can help reduce anxiety and improve vital signs like blood pressure in patients having open heart surgery. The program involves short, guided sessions focusing on breathing and relaxation before and right a…

This study is testing a new smartphone app designed to help teenagers in rural areas manage feelings of anxiety. The app sends personalized tips and activities in real-time when a teen might need support. Researchers will work with 50 teens to see if the app is easy to use, helpf…

This study is testing if a brief, guided tapping technique can quickly reduce anxiety in new parents waiting for their baby's first hearing screening. 70 parents will be randomly assigned to either try the 15-minute technique or simply wait. Researchers will measure anxiety level…

This study is testing whether a short educational video can help people having a heart attack feel less anxious and understand their emergency heart procedure better. About 140 patients will be randomly assigned to receive either the standard medical explanations or the standard …

This study is developing an online program called On-Trac to help adult cancer survivors learn skills to manage anxiety. The program uses techniques from established talk therapies and is delivered through group video sessions and individual coaching. Researchers will test if the…

This study is testing a brief, two-session online therapy program designed specifically for Deaf adults. The goal is to see if this therapy can help change negative beliefs about mental health treatment and encourage more people to seek professional help. Researchers will also ch…

This study is testing a personalized therapy approach for people with anxiety. First, participants track their anxiety symptoms five times a day for two weeks using their phones. Therapists then use this data to create a custom treatment plan, which includes up to 25 weekly couns…

This study is testing if adding ear acupressure (small seeds pressed on specific ear points) to standard nicotine patches or gum helps people in psychiatric hospitals cope better with cravings and anxiety when they can't smoke. It will involve 60 patients who are required to stop…

This study is testing if simple, guided breathing exercises can help reduce the pain and anxiety people often feel when getting needles inserted for their dialysis treatment. It will involve 90 patients who regularly receive dialysis. They will be randomly assigned to try one of …

This study is testing if a single 30-minute audio therapy session can help reduce anxiety in adults with psoriasis. Researchers will measure changes in anxiety, mood, and itch severity before and after participants listen to the audio at home. The goal is to see if this easy-to-a…

This study is testing if a gentle, non-invasive stimulation of a nerve in the ear during heart surgery can help prevent post-surgery confusion (delirium) and reduce feelings of anxiety and depression. About 270 patients having planned heart surgery will be randomly assigned to re…

This study aims to see if listening to relaxing music can help reduce anxiety and improve sleep for people recovering from a heart attack during their first night in the intensive care unit. Researchers will compare a group of 64 patients who listen to 30 minutes of special calmi…

This study is testing whether a specific hand pressure technique, guided by a stress and coping model, can improve quality of life and mental well-being in women going through perimenopause. Sixty women aged 40-54 will learn and practice the hand application daily for two weeks. …

This study is testing if virtual reality (VR) can help reduce pain and anxiety during Pap smears, a test for cervical cancer. Researchers will have 60 women either watch a relaxing nature video through a VR headset or receive standard care during the procedure. The goal is to see…

This study aims to see if adding mind-body therapies like hypnosis and relaxation to standard psychological care helps reduce anxiety in children, teens, and young adults who have survived cancer. It will involve 558 participants aged 7 to 25 who are in remission but experience a…

This study tests whether very short psychological treatments can help reduce symptoms of anxiety, depression, and physical symptoms related to stress. Researchers will compare four or eight sessions of group or individual therapy against a relaxation control group. The goal is to…

This study aims to see if watching an educational video can reduce anxiety in pregnant women who are eligible to try for a vaginal birth after a previous cesarean section (C-section). Researchers will compare the video to standard verbal counseling. The main goal is to measure ch…

This study is testing whether wearing special 'RELAX' glasses can help reduce anxiety in intensive care patients during painful or uncomfortable medical procedures. Researchers will compare anxiety levels in 456 patients who either wear the glasses or receive standard care during…

This study will test if a 4-week online group therapy program delivered over Zoom can help reduce symptoms of anxiety and depression in international students studying in Malaysia. Researchers will compare 128 students who receive the therapy with students on a waiting list to se…

This study is testing if a virtual reality (VR) mindfulness program can help patients feel less anxious and experience less pain during minor vascular surgeries done with local anesthesia. Researchers will enroll 160 patients, with half using the VR program and half receiving sta…

This study is testing whether using a weighted blanket can help pregnant women who experience leg cramps, poor sleep, anxiety, and stress. Fifty women in their third trimester will try using an 8kg weighted blanket for two weeks, after first going two weeks without it. Researcher…

This study aims to find out if daily capsules containing natural ingredients like lavender oil can help adults who feel moderately stressed and have trouble sleeping. Researchers will compare these supplements to a placebo (a dummy pill with no active ingredients) over 8 weeks. T…

This study aims to see if wearing a special 'biofield' skin patch daily for 4 weeks can help reduce anxiety and improve sleep quality. It will compare the active patch to a placebo (inactive) patch in 40 adults who regularly experience anxiety. Participants will answer questionna…

This study is testing if giving a low dose of the drug esketamine during surgery can help reduce anxiety and depression in breast cancer patients who already have mild to severe depression. It will involve 142 women undergoing breast cancer surgery. Researchers will compare those…

This study is testing if watching a 3D hologram during painful burn dressing changes can help distract patients and reduce their pain, anxiety, and fear. It will involve 70 adult burn patients in Turkey, comparing those who use the hologram to those who receive standard care. The…

This study is testing whether community health workers can effectively deliver a mental health program to Spanish-speaking Latino parents experiencing depression, anxiety, or traumatic stress. Researchers will enroll 52 parents and randomly assign them to receive the 14-week prog…

This study tests whether connecting dementia caregivers with trained peer mentors and personalized community resource lists can improve their well-being. Over 330 caregivers will receive education, resource information, and ongoing text message support for 12 months. Researchers …

This study is testing whether a digital mental health app with a peer support community can help improve people's quality of life. Researchers will enroll 82 adults who are not currently in therapy or on medication for a mental health condition. Participants will be randomly assi…

This study is testing if giving a low, continuous dose of a drug called esketamine (related to ketamine) during breast cancer surgery can help reduce the anxiety and depression many patients feel around their operation. It will involve about 218 patients and will measure their em…

This study is testing whether a 10-week program combining strength training and relaxation exercises can help people caring for a family member with Alzheimer's. It aims to reduce their physical frailty, anxiety, and the heavy burden of caregiving. Researchers will compare this c…

This study is testing if using immersive virtual reality (VR) for hypnosis during a coffee break can help reduce anxiety in nurses. It will involve 56 day-shift nurses who will try the VR sessions and report their anxiety levels and satisfaction. The goal is to see if this non-dr…

This study will test a 6-week group therapy program designed to help trans and gender diverse teenagers cope with stress from discrimination and rejection. The program, created with input from trans youth, teaches skills to manage anxiety and depression and build community connec…

This study is testing whether combining hypnosis with calming scents (aromatherapy) can help reduce anxiety in people going through alcohol withdrawal. Researchers will compare this combined approach to standard hospital care. The study will involve 80 adults hospitalized for alc…

This study aims to see if taking a daily probiotic supplement for 8 weeks can help reduce feelings of stress and anxiety in healthy university students during exam periods. Researchers will compare the probiotic against a placebo (dummy pill) in 200 students. They will measure ch…

This study aims to see if simple, drug-free methods can help new mothers feel better during a common medical procedure. Researchers will test whether listening to relaxing music or chewing gum can reduce pain and anxiety for women getting stitches (an episiotomy repair) after vag…

This study aims to see if a drink called Feel Free® Classic Tonic can help reduce feelings of stress and anxiety in healthy adults. Researchers will give 165 participants either the tonic or a placebo for 29 days and measure changes in their self-reported stress, anxiety, and phy…

This study is testing whether a special chaplain-led support program can help family members who are making medical decisions for a critically ill loved one in the ICU. It aims to reduce their anxiety and improve their spiritual well-being during this stressful time. The program …

This study aims to see if a simple drawing activity can help reduce anxiety in adults waiting for elective surgery. Researchers will test whether using different colors and shapes in the drawing task makes a difference. They will measure anxiety levels, heart rate, and how engage…

This study will test if a guided self-help workbook based on Cognitive Behavioral Therapy (CBT) can help cancer patients manage anxiety and depression. About 108 adult cancer patients in Pakistan who can read Urdu and are experiencing psychological distress will participate. The …

This study is testing whether a simple handheld device can make it easier for cancer patients to get their IV chemotherapy. Patients will squeeze a palm-sized device with bumps during the needle insertion to see if it reduces pain and fear. The goal is to provide a drug-free, eas…

This study is testing whether listening to binaural beats (special audio tones) or music of your choice can help reduce pain and anxiety right after knee or hip replacement surgery. Researchers will compare these audio methods in 50 adults recovering from surgery. They will measu…

This study is testing whether a new smartphone app can help teenagers who hurt themselves on purpose (nonsuicidal self-injury). The app uses a chatbot to teach coping skills and provide support. Researchers want to see if the app is easy to use and acceptable to teens before laun…

This study is testing if using virtual reality (VR) can help adults feel less pain, anxiety, stress, and loneliness while they are in the hospital. Researchers want to see if using VR with a trained guide works as well as using it alone. They will enroll 200 stable adult patients…

This study is testing whether a four-week virtual yoga program can help people feel better emotionally while going through IVF treatment. Researchers want to see if weekly yoga classes improve quality of life and reduce feelings of anxiety and depression. They will compare a grou…

This study is testing whether adding virtual reality (VR) sessions to standard university counseling helps students manage public speaking anxiety better than counseling alone. 72 students with moderate anxiety will be randomly assigned to receive either standard counseling or co…

This study aims to see if giving the drug esketamine during surgery can help reduce anxiety and depression symptoms in breast cancer patients who also have severe depression. It will involve about 240 female patients undergoing breast cancer surgery. Researchers will compare thos…

This study is testing whether using virtual reality (VR) headsets during a breast biopsy can help reduce patients' feelings of depression, anxiety, and stress. 80 patients in Palestine will be randomly assigned to either use a calming VR environment during their procedure or rece…

This study is testing whether a program combining yoga, meditation, and mindful eating can help university students feel less stressed, anxious, and depressed. About 60 students will attend weekly sessions for one semester, practicing physical postures, breathing exercises, and l…

This study is testing whether a portable home device called the Freespira Breathing System can help reduce anxiety and panic symptoms in children and teenagers. Researchers at Johns Hopkins University will enroll 73 young people aged 9-17 who have been diagnosed with an anxiety d…

This study is testing if a gentle, non-invasive stimulation of a nerve in the ear during breast cancer surgery can help reduce feelings of anxiety and depression that often occur around the time of an operation. About 232 patients will be randomly assigned to receive either the r…

This study is testing whether a special music therapy app, used alongside standard addiction treatment, can help adults with trauma histories better manage their emotions, anxiety, and stress. About 100 adults in residential treatment for substance use will use the app for a week…

This study is testing whether a natural herb called ashwagandha can help reduce stress, anxiety, and improve sleep for LGBTQ+ adults who experience chronic stress from discrimination. 80 participants will take either ashwagandha or a placebo pill for 8 weeks. Researchers will mea…

This study aims to see if showing a short educational video to new mothers can reduce their anxiety and pain before they receive a necessary postpartum blood thinner injection. The trial will compare the standard verbal explanation nurses give to the same explanation plus a brief…

This study is testing whether listening to guided meditation recordings can help reduce stress and anxiety in patients undergoing open-heart surgery. Researchers will compare 72 patients who receive the meditation sessions to those who receive standard care alone. They will measu…

This study aims to see if structured group therapy can help reduce symptoms of depression and anxiety in Pakistani adults. It will compare two types of group sessions: one focused on changing thought patterns (CBT) and another on mindfulness and stress reduction. The goal is to p…

This study aims to see if a specific type of acupressure, timed to the body's natural daily rhythms, can improve sleep quality for older adults living in a nursing home. Researchers will compare this timed acupressure to a sham (fake) acupressure treatment. The goal is to find a …

This study aims to see if teaching mindfulness skills can help reduce depression, anxiety, and stress in pregnant women who are hospitalized because they are at risk of delivering their baby too early. It will involve 60 participants who will either receive weekly mindfulness coa…

This study aims to see if the medication buspirone can safely help reduce anxiety in children and teenagers with autism. About 20 participants, aged 7 to 17, will take either buspirone or a placebo (a pill with no medicine) for 16 weeks. Researchers will measure changes in anxiet…

This study is testing if a guided breathing and relaxation technique can help reduce anxiety in adults who are in the intensive care unit (ICU) waiting for a heart transplant. About 60 participants will learn the technique, which uses a device or app to help them control their br…

This pilot study is testing a new 'blended' therapy format that combines standard face-to-face therapy sessions with a smartphone app. It aims to see if this approach is practical and helpful for reducing symptoms of anxiety and depression in adults visiting their primary care do…

This study tests whether showing children a virtual reality (VR) tour of an MRI machine before their scan can help them feel less anxious and stay still. Researchers will compare three groups: kids who watch the VR tour at home and again at the hospital, kids who watch it only at…

This study is testing a new brain training method to help reduce anxiety in women who have experienced multiple miscarriages. Researchers will use a special cap to measure brain activity and guide participants to calm their minds, while also tracking their heart rate. The goal is…

This study is testing if a special AI-made video story can help children feel less anxious and fearful before their first skin prick allergy test. Kids aged 4-10 will be split into two groups: one watches the video at home before their appointment, and the other gets the clinic's…

This study aims to see if using distraction methods can make allergy skin prick tests less scary and painful for children. Researchers will compare virtual reality headsets and a vibrating 'Buzzy' device against standard care in 111 kids aged 7-10. The goal is to find better ways…

This study aims to see if melatonin, a natural sleep hormone, works as well as the standard drug midazolam at reducing anxiety in children before tonsil removal surgery. It will involve 195 healthy children and will also measure confusion after waking up from anesthesia. The goal…

This study is testing a mental health support program for family members of people who have survived intensive care. The program uses a telehealth platform to help families manage anxiety, depression, and stress. Researchers want to see if this approach is practical and helpful f…

This study tests whether a digital mental health program helps people recovering from intensive care. 150 patients will either use a special app with coaching and support or receive standard follow-up care. Researchers will compare anxiety, depression, and PTSD symptoms after six…

This study is testing whether a group therapy retreat using psilocybin, the active compound in 'magic mushrooms,' can safely help reduce anxiety and depression in adults with advanced cancer. Participants will take a single dose of psilocybin in a controlled setting, supported by…

This study aims to find out why some people get better with anxiety treatment while others don't. About 4,400 adults with anxiety will use a digital brain-training program called LENS, which helps reduce negative thinking. Researchers will then track participants' thinking patter…

This study aims to understand how magnetic stimulation of a specific brain area affects anxiety. Researchers will use brain scans and anxiety tests on 140 people with high anxiety to see how stimulation changes brain activity and anxiety responses. The goal is to gather evidence …

This study investigates how online cannabis ads that claim to help with anxiety and depression affect what people buy. Researchers will have 2000 adults with symptoms of anxiety or depression use a simulated online cannabis store. They will test if these therapeutic claims make p…

This study aims to understand if anxiety about climate change is connected to suicidal thoughts in young people. Researchers will survey 108 participants aged 16 to 24 in France who are receiving psychiatric care. By comparing answers on climate anxiety and suicide risk questionn…

This study aims to test a short, 3-5 minute communication program designed to improve mental health and public attitudes in Nigerian communities affected by conflict. It will involve about 74 adult residents to see if the program is practical and acceptable. The goal is to reduce…

This study aims to understand if specific patterns of harmful gut bacteria are linked to anxiety, depression, and panic disorders. Researchers will compare stool samples from 500 adults with these conditions to samples from healthy individuals. The goal is to gather new evidence …

This study aims to understand how the brain creates avoidance behavior in people with anxiety. Researchers will use brain scans and decision-making tasks to measure brain activity patterns linked to avoiding threats. They will also track participants' daily movements and behavior…

This study aims to understand the specific worries of patients who feel anxious before planned surgery. Researchers will interview 30 patients with high anxiety scores to learn how their concerns might be linked to developing long-term pain after an operation. The goal is to use …

This study aims to understand if a patient's anxiety level before getting spinal anesthesia affects their chance of having a vasovagal event, like fainting or a sudden drop in heart rate and blood pressure, during the procedure. Researchers will measure anxiety in 1,500 adults be…

This study is looking back at data from a 12-week wellness program designed for veterans and first responders. Researchers will analyze information from about 80 past participants to see if the program helped with anxiety, depression, PTSD, sleep, and overall quality of life. The…

This study aims to understand if a single session of magnetic brain stimulation can affect heart rate and heart rate patterns in women who have experienced multiple miscarriages and also have anxiety. Researchers will compare real stimulation to a fake (sham) stimulation in 46 pa…

This study aims to understand how common anxiety and depression are among medical students and interns at Assiut University. Researchers will survey about 289 students to identify what factors might increase their risk and how mental health relates to their academic performance. …

This study is a one-time survey asking urology patients if they use AI chatbots like ChatGPT to look up health information before their appointment. Researchers want to see if using these tools affects how anxious patients feel, how satisfied they are with their visit, or how wel…