Gut feelings: could everyday prebiotics calm anxiety and improve sleep?

NCT ID NCT07752823

Not yet recruiting Symptom relief Sponsor: Holobiome, Inc. Source: ClinicalTrials.gov ↗

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This large citizen-science trial is testing whether two prebiotic products can reduce feelings of anxiety and improve related outcomes like sleep in adults. Around 1,000 participants will be randomly assigned to take either an active prebiotic or a placebo for 12 weeks, without knowing which they receive. Researchers will track changes in anxiety scores, sleep quality, and safety to see if these products offer a natural way to support mental wellness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Prebiotic products (Active Gut Feeling Product 1 and 2) compared with placebo
What this could lead to: If these prebiotics work, they could offer a natural, accessible way to help ease anxiety and improve sleep and overall mental wellness.
What could go wrong: This is an early-stage trial, and the effects may be small or no better than placebo. Prebiotics can also cause digestive discomfort in some people.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder Parasomnias sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FEELING ANXIOUS SLEEP DISTURBANCE STRESS

Contacts and locations

Locations

Radicle Science Inc.

Del Mar, California, 92014-2605, United States

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