STRESS

This study tests whether special air cleaners and ventilators can reduce indoor pollutants and mold, helping people with asthma breathe easier. About 80 children and adults with asthma from low-income households in the Dallas-Fort Worth area will receive either real or placebo de…

This study is testing whether a wearable device called WAVwatch 2.0, which plays sound frequencies, can help reduce stress and improve mental well-being. About 100 adults in the US who can read English will use the device and report their stress, anxiety, and life satisfaction le…

This study tests whether a community health worker (called a promotora) can help Latinx and Native American adults with moderate to high stress find mental health services and feel better. About 80 adults will be randomly assigned to either work with a promotora or receive usual …

This study tests whether the JoyPop app can help 110 teens aged 12-17 in Canada better manage their emotions and reduce depression, anxiety, and stress while they wait for mental health services. Participants will either use the app or continue with usual care. The goal is to see…

This study looks at whether taking L-tyrosine, a natural amino acid, can help lower stress in people having outpatient hernia surgery. About 150 adults will take either L-tyrosine or a placebo before their operation. The goal is to see if it reduces anxiety without affecting reco…

This study tests whether a tonic called Feel Free® Classic can help healthy adults feel less stressed. About 165 people aged 21-55 with mild to moderate stress will take the tonic or a placebo for 29 days. Researchers will measure stress levels and how the body processes the toni…

This study looks at whether music therapy can improve mental health and social connections in university students who feel depressed, anxious, or stressed. Twenty students aged 18-40 will be randomly assigned to either music therapy sessions or non-therapeutic music listening. Re…

This study tests whether adding a special supplement to a mindfulness program helps college students aged 18-25 feel less stressed, anxious, or depressed. About 120 students with high stress will join one of three groups: mindfulness only, mindfulness plus supplement, or a health…

This study tests whether combining neurofeedback (a brain training technique) with mindfulness can lower anxiety and stress and improve grades in nursing students. About 36 students aged 18-45 will take part. The goal is to see if this approach helps them handle academic pressure…

This study aims to help caregivers of justice-involved youth (ages 12-17) who are in detention or group homes. Researchers are developing and testing a mobile health app to reduce parenting stress, which often keeps youth from getting substance use treatment. About 60 caregivers …

This study tests whether using a virtual reality headset (REALICA) can help reduce pain and anxiety in people undergoing common outpatient urology procedures like prostate biopsy, cystoscopy, or circumcision. About 56 adults will use the VR device during their procedure and repor…

This study is testing whether college students can be trained to deliver cognitive-behavioral therapy (CBT) to high school students in rural areas. The goal is to reduce symptoms of depression, anxiety, and stress in teens aged 13 to 18. The program aims to make mental health sup…

This study tests whether inhaling lavender essential oil for four weeks can improve mental health in 120 women waiting for IVF treatment. Participants are split into three groups: one gets real lavender, one gets a placebo scent, and one gets no scent. The goal is to see if aroma…

This study tests whether a 4-week digital program that sends activity prompts can increase physical activity and reduce depression, anxiety, and stress in adults with moderate symptoms. Fifty participants will be randomly assigned to receive the prompts or just have their symptom…

This study tests whether personalized music playlists can help adults reduce stress, anxiety, and depression. 2000 participants will either receive custom playlists or no music intervention. The goal is to see if music can be a simple, non-drug tool for improving emotional well-b…

This study tests whether natural supplements like lavender oil, PEA, and OEA can help adults with moderate stress and sleep problems. About 240 participants will take a daily capsule for 8 weeks, and researchers will compare the supplements to a placebo. The goal is to see if the…

This study tests whether a daily nasal spray of oxytocin, a natural hormone, can lower stress and improve quality of life in female family caregivers of people with dementia. About 32 women aged 50 and older who provide unpaid care will receive either a low dose, a higher dose, o…

This study looks at whether listening to live or recorded music can help lower stress, pain, and improve mood in people about to have brain surgery. Researchers will check things like heart rate, stress hormones, and how patients feel using simple questionnaires. The goal is to f…

This study tests whether taking a daily postbiotic supplement called Humiome® Post LB for three months can lower stress levels in adults aged 50 to 75. Two hundred participants in France will either receive the supplement or a placebo, and their stress will be measured using a st…

This study is testing whether a daily supplement called AGZ can help adults aged 25-59 who have trouble sleeping feel more relaxed in the evening, sleep better, and wake up feeling refreshed. 300 participants will take AGZ or a placebo for 30 days and answer questionnaires about …

This study tests whether a mindset management program called Organic Conceptions can lower stress levels in women dealing with infertility. About 66 women who are new patients at a fertility clinic will take part. Half will complete the program and all will fill out surveys to me…

This study tests whether a smartphone app called JoyPop can help young adults (ages 18-25) better manage their emotions, anxiety, and depression while they wait for mental health services. About 110 participants from Northwestern Ontario will either use the app or continue with u…

This study tests whether an 8-week stress reduction program can reduce inflammation in the arteries of adults aged 30-65 who feel stressed. Researchers will use special scans to measure changes in artery inflammation. The goal is to see if managing stress can improve heart health…

This study tests whether taking a prebiotic fiber blend every day for 12 weeks can lower stress levels in healthy adults who feel mild to severe stress. Participants will take either the fiber powder or a placebo and report their stress, mood, and anxiety. The goal is to see if c…

This study tests a mobile app program called PRISM to help teens and young adults (ages 12-25) who have finished cancer treatment build resilience and manage stress. Participants will use the app for six sessions of skills training. The goal is to see which delivery method (video…

This study is testing whether a self-guided online course that teaches dialectical behavior therapy (DBT) skills is practical and helpful for adults with mild-to-moderate depression and anxiety. About 40 participants will take the 8-week course and complete surveys to measure how…

This study looks at whether a relaxing therapy called Reiki can help adults with cancer who feel very tired from immunotherapy. Twelve people will either get six weekly Reiki sessions right away or wait six weeks before starting. Researchers will track changes in fatigue, pain, a…

This study tests whether a breathing technique called SKY can help college students manage stress and anxiety. About 53 students will be split into two groups: one learns SKY breathwork, the other does general yoga. Over 8 weeks, researchers will check if the program is easy to f…

This study tests whether a 6-week music class (drumming and rhythm exercises) can reduce stress, anxiety, depression, and chronic pain in older adults living in residential care. About 60 participants will attend weekly hour-long sessions and complete surveys before and after. Th…

This study tests whether taking magnesium and vitamin B6 alongside standard treatment can reduce symptoms of depression, anxiety, and stress in people who have recently been diagnosed with bipolar I disorder. About 40 adults aged 18 to 50 with a first episode in the last 10 years…

This study tests a two-week smartphone program designed to help people who struggle to feel pleasure (anhedonia) and also experience depression, anxiety, or stress. Participants do three short daily exercises like savoring good moments or finding silver linings, delivered via aud…

This study tests a mobile app called Blueprint that teaches coping skills to people who survived a serious illness in the ICU. Many survivors struggle with anxiety, depression, and PTSD, but few have access to mental health care. The app aims to help them manage these symptoms on…

This study tests whether simple neck exercises and posture advice can reduce headaches, stress, and sleep problems in teens aged 13-19 who use smartphones for 4+ hours daily and have cervicogenic headaches (headaches from neck strain). Researchers will measure changes in headache…

This study looks at whether eating nuts can help reduce symptoms of depression, anxiety, and stress in young adults aged 18 to 25. Researchers will also measure memory, thinking skills, and a brain-related protein called BDNF. A total of 135 university students will be randomly a…

This study compares two breathing techniques (cyclic sighing and box breathing) with hypnosis and listening to an audiobook about stress. Researchers want to see if these practices can lower anxiety right away and after four weeks of daily use. About 80 adults will participate, a…

This study looks at whether cannabidiol (CBD) can reduce stress and withdrawal symptoms in people who smoke cigarettes. About 90 smokers will take CBD and then be exposed to stress. Researchers will measure mood, heart rate, and stress hormones to see if CBD helps. Some participa…

This study tests a workplace program for healthcare workers that combines mind-body techniques, self-care strategies, and special nutrition to boost stress resilience and reduce burnout. About 252 employees from University Medicine Essen will take part. If it works, the program c…

This study is testing whether yoga can help pregnant women in their third trimester feel less stressed, sleep better, and have a better quality of sex life. About 70 women will take part—half will do yoga sessions, and the other half will not. Researchers will measure stress, sle…

This study tests a culturally adapted internet-based therapy (i-CBT) for Farsi/Dari-speaking migrants and refugees aged 15-29 who have symptoms of anxiety, depression, or stress. Participants will receive the therapy or be in a control group. The goal is to see if this approach r…

This study tests whether a one-week smartphone training program can help unpaid caregivers of people with Alzheimer's disease manage stress and emotions better. About 270 caregivers will learn either distancing or reinterpretation techniques, or receive no training. Researchers w…

This study looks at whether swaddling (wrapping snugly) or nesting (creating a cozy boundary) can lower pain and stress in newborns who need breathing help. About 100 babies born after 35 weeks will be observed. Researchers will check heart rate, oxygen levels, and use a special …

This study explores whether a daily mindfulness practice using Tao Calligraphy and Song can help adults feel less stressed, more connected to others, and more at peace. Fifty participants will be randomly assigned to either practice these techniques for 30 minutes daily or join a…

This study tests a new online program called MB-Spirit to see if it can improve well-being in stressed adults. Participants take an 8-week course and complete questionnaires and brain scans. The goal is to understand how the program affects mental health and brain function.

This study tests whether a nutritional drink called 'Think Tank' can help middle-aged women (40-60 years old) think more clearly after experiencing stress. Forty healthy women who drink caffeine daily will take either the drink or a placebo and then complete thinking and memory t…

This study tests a program called ACT Together for parents of children with disabilities. It includes six online lessons and weekly phone coaching with an occupational therapist to help parents handle stress and difficult emotions. About 60 parents and therapists will take part t…

This study offers a free 6-week online psychological coaching program for NSU undergraduate students. The goal is to help reduce symptoms of anxiety, depression, and stress while improving quality of life and healthy coping skills. Participants will complete surveys before and af…

This study tests whether using virtual reality (VR) goggles or a sedative drug called dexmedetomidine is better at reducing anxiety and stress in women having a planned cesarean section. About 52 mothers will be randomly assigned to one of the two methods. The goal is to find a s…

This study tests whether virtual reality nature scenes and special sound patterns (binaural beats) can reduce stress in healthy adults. About 52 participants will attend a single 30-minute session, with some using VR or listening to sounds, while others serve as a control group. …

This study tests whether a mobile app called JoyPop can help Indigenous youth aged 18-25 in Northwestern Ontario manage their emotions and reduce stress while they wait for mental health services. Participants will either use the app or receive usual care. The goal is to see if t…

This study tests whether a 6-week online mindfulness-based stress reduction (MBSR) program can lower stress, anxiety, depression, and other side effects in women with breast cancer who are starting chemotherapy. About 200 participants will be randomly assigned to either the onlin…

This study tests whether a 10-session parenting program called Attachment and Biobehavioral Catch-up (ABC) can lower stress-related biomarkers in children aged 2 to 3 who have experienced early life adversity. About 150 caregiver-child pairs will be randomly assigned to receive t…

This study tests whether a 14-day mobile daily diary is a practical way to measure daily stress and thinking (cognitive) performance in breast cancer survivors from different racial backgrounds. Researchers will enroll 30 women aged 40 and older who are at least five years past t…

This study looks at how healthy behaviors like exercise, diet, stress, and sleep are linked to heart health measures such as blood pressure and cholesterol. Researchers will collect information from 100 adults and children through questionnaires and simple health checks. The goal…

This study looks at how searching the internet for health information affects stress and emotional well-being in women undergoing infertility treatment. About 200 women will fill out surveys about their online search habits, stress levels, and emotional health. The goal is to und…

This study looks at how poor sleep during pregnancy can increase stress and the risk of mental health issues like depression and anxiety after giving birth. Researchers will follow 114 pregnant women and test an online, automated therapy designed to improve sleep. The goal is to …

This study looks at how stress and childhood trauma might increase the risk of preterm birth by affecting tiny energy-producing parts of cells called mitochondria. Researchers will follow 200 pregnant women, mostly Black and Hispanic, to understand these connections and why prete…

This study looks at how cannabidiol (CBD), a non-intoxicating cannabis compound, affects stress responses in 160 young adults aged 18-25 who experienced early life adversity. Researchers will use brain scans, blood and saliva tests, and stress questionnaires to understand how CBD…

This study looks at how acute stress affects the brain's energy use and connections in 68 healthy adults. Participants will have two brain scans one week apart while doing a stress test. The goal is to understand why some people handle stress better than others, which could help …

This study looks at whether an 8-week stress reduction program can lower inflammation in the arteries of people with stable heart disease. About 36 adults who feel stressed will learn mindfulness techniques and get special PET/MRI scans to measure changes. The goal is to see if c…

This study looks at whether using video recordings from an 'Operating Room Black Box' during team debriefings after surgery helps staff feel more psychologically safe and work better together. About 135 operating room staff from three hospitals will take part. The goal is to see …

This study looks at how adding chia seeds to your diet changes the bacteria in your gut and related immune markers. About 60 healthy adults will take a daily fiber supplement for two months. Researchers will collect stool and blood samples to measure changes in gut microbes and i…

This study tests a program called RiSE that teaches African American women ways to handle stress from racism. Researchers want to see if it lowers inflammation and improves well-being. About 300 women aged 50-75 with heart or metabolic risks will join online classes for 8 weeks a…

This study tests a program called FRAME that helps heart failure patients discuss mental health with their doctors and loved ones. About 7,300 adults with heart failure or at risk for it will take part in clinics across Ontario, Canada. The goal is to see if the program is practi…

This study looks at how stress and pain affect hormones and mood in 120 people with or without HIV, cannabis use disorder, and depression. Participants will do a pain stress task and give blood samples to measure stress chemicals. The goal is to understand these connections, not …

This study looks at how body composition (fat versus muscle) affects blood vessel health in women who have a normal BMI. Researchers will measure how blood vessels respond to a high-fat meal and a stress task. The goal is to understand why some normal-weight people may still have…

This study tests a training program called ASCEND, developed by the World Health Organization, for supervisors in small and medium-sized businesses in the Netherlands. The goal is to see if the training helps supervisors better support their employees' mental health, reduce stigm…

This study is testing whether a smartphone app can help firefighters improve their sleep, thinking, and overall well-being. About 50 firefighters will use the app and report on their sleep habits. The goal is to see if the program is easy to use and helpful for this group.

This study looks at how negative feelings like stress, pain, or hunger change the way people make decisions. Healthy adults aged 18 to 55 will experience different emotional triggers (like watching a sad video or putting a hand in ice water) and then perform computer tasks. Some …

This study looks at whether playing music or music with a parent's voice can lower stress and improve brain development in very preterm babies (born between 24 and 30 weeks). About 243 infants from two hospitals will be randomly assigned to hear music, music with parent voice, or…

This study looks at why depression and heart disease often occur together in women going through menopause. Researchers will measure stress-related chemicals and heart rate in 30 women aged 44-55 to see if changes in these pathways explain the link. The goal is to find new ways t…

This study looks at how sleep problems and stress can trigger migraine attacks. Adults with episodic migraine wear a WHOOP band to track sleep and body signals, and answer daily questions on a smartphone app. The goal is to find personal patterns and give tailored advice to impro…

This study looks at how stressful events in childhood may impact heart and blood vessel health later in life. Researchers will measure heart function, blood vessel response, and lung function in 120 people aged 9 to 30. The goal is to understand the connection between early stres…

This study looks at how nomophobia—the fear of being without your smartphone—relates to stress, food addiction, and body image in 150 university students aged 18-30. Participants will fill out questionnaires and have body measurements taken. The goal is to understand connections …

This study looks at whether giving parents of children with chronic conditions a mental health questionnaire during clinic visits can help identify stress, anxiety, or depression. About 100 parents will fill out the survey, get their results, and receive a list of support service…

This study looks at how a brief full-body cold-water bath changes the way people make decisions, their mood, and body signals like heart rate and stress hormones. Forty healthy adults will take both a cold and a warm bath on different days and then complete tasks measuring risk-t…

This study looks at how stress changes the way opioid painkillers work in people with long-term back pain. Researchers want to understand if high stress levels make it more likely for someone to misuse their pain medication. About 120 adults with daily back pain will take part in…