STRESS

This study is testing whether an 8-week online program called RiSE, which teaches stress management skills with a focus on coping with racism, can improve well-being and reduce body inflammation in African American women who are at risk for heart and metabolic diseases. Researche…

This study is developing and testing a mobile phone app designed to help parents and caregivers manage their stress. The goal is to see if reducing this stress makes it easier for caregivers to support their teenagers who are leaving juvenile detention and need substance use trea…

This study is testing whether an 8-week mindfulness and stress reduction program can reduce inflammation in the arteries of people with stable heart disease. Researchers will use PET and MRI scans to measure artery inflammation before and after the program in 36 adults who report…

This small pilot study is testing whether an 8-week stress reduction program can reduce inflammation in the arteries of adults who feel highly stressed. About 30 participants will be randomly assigned to either learn mindfulness and relaxation techniques or receive no interventio…

This study is testing whether installing special air cleaners or ventilators in homes can improve air quality and help people with asthma breathe easier. Researchers will compare real devices to fake ones in 80 low-income households in Texas over two years. They will measure air …

This study tests whether an online sleep improvement program for pregnant women can prevent postpartum depression and stress. Researchers will follow 114 women from early pregnancy until six months after birth, measuring sleep quality, stress hormones, and mental health. The goal…

This study is testing a World Health Organization (WHO) training program designed to help supervisors better support their employees' mental health at work. Researchers will enroll 148 supervisors from small and medium-sized Dutch companies, with half receiving the training immed…

This study is testing whether taking a daily powdered prebiotic fiber blend for 12 weeks can help reduce feelings of stress, improve mood, and ease anxiety in healthy adults. Researchers will compare the fiber supplement to a placebo (a look-alike powder with no active ingredient…

This study is testing whether a smartphone app called JoyPop can help young adults (ages 18-25) manage difficult emotions, stress, anxiety, and depression while they are on a waitlist for professional mental health services. Researchers in Northwestern Ontario will compare the ap…

This study is testing whether playing specially designed music, sometimes with a parent's recorded voice, can help very premature babies in the hospital. Researchers want to see if this reduces the babies' stress, helps their brains develop better, and improves their language ski…

This study is testing whether a specific type of music therapy, where students write songs, can help reduce feelings of depression, anxiety, and stress while improving social connections. Researchers will compare songwriting sessions to simple music listening and discussion in 20…

This study is testing if adding an over-the-counter magnesium and vitamin B6 supplement to standard treatment can help reduce symptoms of depression, anxiety, and stress in adults recently diagnosed with bipolar I disorder. Researchers will compare the supplement to a placebo (in…

This study is testing whether a nutritional drink called 'Think Tank' can help improve mental sharpness and well-being after someone experiences stress. Researchers will recruit 40 healthy women aged 40-60 to see if the drink helps with memory, focus, and mood better than a place…

This small pilot study is testing whether a specific breathing meditation program called SKY can help reduce stress and anxiety in college students. 56 students will be randomly assigned to either the SKY program (which includes a retreat and weekly sessions) or a general online …

This study is testing whether a new program called FRAME helps people with heart failure talk about and get support for mental health issues like stress, anxiety, and depression. About 7,300 patients at clinics in Ontario, Canada, will use the FRAME tool and answer surveys before…

This study is testing whether a phone app and monthly coaching calls can help firefighters get better sleep. Fifty firefighters will try the app for three months, tracking sleep and learning healthy habits, while others receive basic sleep information. The main goal is to see if …

This study is testing whether taking a dietary supplement called kava extract can help reduce stress and feelings of burnout in nurses. Researchers at Mayo Clinic will enroll 200 surgical nurses to see if kava lowers the stress hormone cortisol and improves their mood, sleep, and…

This study is testing whether a yoga program can help reduce stress, improve sleep habits, and enhance sexual quality of life for women in their third trimester of pregnancy. Researchers will compare 35 pregnant women doing yoga with 35 who do not. The goal is to see if this gent…

This study is testing a type of talk therapy to see if it helps improve mental health for men who are HIV-positive. It will involve 24 participants and focuses on reducing symptoms of stress, anxiety, and depression. The goal is to see if this therapy is practical and effective f…

This study is testing whether a supplement called AGZ can help people feel more relaxed in the evening, sleep better, and have more energy in the morning. It will involve 300 generally healthy adults in the US who currently have trouble with their sleep. Participants will take th…

This study is testing whether a one-month program of specific neck exercises and posture advice can reduce headaches, stress, and sleep problems in teenagers who use smartphones heavily. Researchers will measure changes in headache pain, stress hormones, and sleep quality. The go…

This study is testing whether a prenatal yoga app can improve the well-being of first-time Black and African American pregnant women. Researchers want to see if using the app for 12 weeks is practical and helps with stress, mood, and physical health. The study also aims to learn …

This study is testing a mobile app called Blueprint, designed to help people manage depression, anxiety, and PTSD after surviving a serious heart or lung condition in the hospital. Researchers will enroll 400 people from four hospitals and randomly assign them to use either the B…

This study is testing whether a smartphone app called JoyPop can help Indigenous young adults (ages 18-25) manage difficult emotions like stress, anxiety, and depression while they wait for formal mental health services. Researchers will compare the app's effects to usual waitlis…

This study is testing whether a wearable device called the WAVwatch 2.0, which plays sound frequencies, can help reduce everyday stress and anxiety. It will involve 100 adults in the US who will use the device and report on their stress levels. The goal is to see if this technolo…

This study is testing whether smelling lavender essential oil can help improve mental health and quality of life for women waiting to undergo IVF treatment. It will involve 120 women who are feeling anxious or stressed. Participants will be split into three groups: one will smell…

This study aims to find out if swaddling or nesting works better to reduce pain and stress in newborns who need help breathing. Researchers will compare these two common, gentle care methods in 100 infants. They will measure stress using heart rate, breathing, and a simple saliva…

This study is testing a 10-week online therapy program designed specifically for Farsi/Dari-speaking young migrants and refugees. It aims to help reduce symptoms of anxiety, depression, grief, and stress. Participants will be randomly assigned to either receive the therapy immedi…

This study is testing whether a smartphone app called JoyPop can help teenagers manage difficult emotions, stress, anxiety, and depression while they wait to start formal mental health therapy. Researchers will compare 110 teens aged 12-17 who use the app to those who receive usu…

This study is testing whether relaxing sounds and virtual reality (VR) experiences can help reduce stress in healthy adults. Participants are randomly assigned to try different combinations of natural soundscapes, VR nature scenes, or a control group during a single 30-minute ses…

This study is testing a brief, one-week smartphone training program designed to help unpaid family caregivers of people with Alzheimer's disease manage their emotions and stress. Researchers will enroll 270 caregivers to learn different mental techniques, like psychological dista…

This study is testing a new 8-week online meditation program called MB-Spirit to see if it can improve well-being and reduce stress in adults. Researchers will enroll 44 stressed adults, who will either take the course immediately or be placed on a waitlist. The study will use qu…

This study is testing whether daily breathing exercises can help reduce anxiety and stress. Researchers will compare two breathing techniques against hypnosis and an educational audiobook over 4 weeks. They will measure changes in participants' anxiety levels, brain activity, and…

This study is testing if a dietary supplement called L-tyrosine can help reduce anxiety and stress in adults having outpatient hernia surgery. Researchers want to see if taking L-tyrosine improves the body's ability to handle the stress of surgery without causing drowsiness or de…

This study is testing whether a combination of mindfulness and a brain training technique called neurofeedback can help reduce stress and anxiety in nursing students. It will involve 36 students from the University of Salamanca who will use these techniques over four weeks. The m…

This study is testing a new online program designed to help parents of children with disabilities manage stress, anxiety, and depression. Parents will complete six online modules and receive brief weekly phone coaching from a trained occupational therapist. The research aims to s…

This study is testing whether a simple phone app that sends daily reminders can help people with depression become more physically active and feel better. Researchers will compare a group using the app for four weeks to a group that does not use it. They want to see if the app in…

This study is testing whether adding a daily smartphone-based supplement to a standard mindfulness group program can better help college students manage stress, anxiety, and depression. Researchers will compare this combined approach to the mindfulness program alone and to a gene…

This study is testing the best way to deliver a mobile app program called PRISM, which teaches skills to manage stress and build resilience. It aims to help adolescents and young adults (ages 12-25) cope with anxiety and depression after finishing their main cancer treatment. Res…

This study is testing a new workplace health program designed to help doctors, nurses, and other hospital staff better manage stress and prevent burnout. The program combines mindfulness techniques, self-care strategies, and nutrition advice focused on gut health. Researchers wil…

This study is testing whether listening to live or recorded music before brain surgery can help reduce patients' stress, anxiety, and pain. Researchers will measure changes in vital signs, blood markers, and patient questionnaires in 132 adults. The goal is to see if music is a h…

This study is testing whether a 10-week online mindset management program can help reduce stress in women dealing with infertility. Researchers will enroll 66 women and randomly assign them to either complete the program or receive standard care. They will compare stress levels b…

This study is testing a two-week smartphone app program designed to help people who struggle to feel pleasure (anhedonia) and experience high stress, anxiety, or depression. Participants are randomly assigned to use an app with daily audio exercises focused on gratitude, positive…

This study is testing a new program where college students are trained to provide therapy to high schoolers in rural Pennsylvania. The goal is to see if this approach can effectively reduce symptoms of depression, anxiety, and stress in teens who often have limited access to ment…

This study is testing two different ways to help mothers feel less anxious and stressed during a planned cesarean section. It will compare a sedative medicine given through an IV with a non-drug approach using virtual reality (VR) goggles. Researchers will measure the mothers' an…

This study is testing whether listening to personalized music playlists can help adults reduce feelings of stress, anxiety, and depression. Researchers will assign 2,000 participants to either receive specially designed music or no music intervention. The goal is to see if this a…

This study is testing whether a daily nasal spray containing oxytocin, a natural hormone, can help reduce chronic stress and improve quality of life for women who are family caregivers for someone with dementia. Researchers will enroll 32 female caregivers to receive either a low…

This study is testing whether using a virtual reality (VR) headset during common outpatient urology procedures can help reduce patients' pain and anxiety. It will involve 56 adults undergoing procedures like prostate biopsy, cystoscopy, or circumcision. The goal is to see if this…

This study is testing whether a 6-week online mindfulness course can help reduce stress and other treatment-related symptoms for women with breast cancer who are receiving chemotherapy. Researchers will compare 200 participants who either take the course or receive no interventio…

This study is testing a free, 6-week online coaching program designed to help Nova Southeastern University undergraduate students manage anxiety, depression, and stress. About 160 students will be randomly assigned to either start the program immediately or be placed on a waitlis…

This study is testing whether a specific parenting program can reduce stress levels in young children who have faced difficult life circumstances. About 150 caregivers and their toddlers will be randomly assigned to either receive the 10-session program right away or be placed on…

This study aims to understand how cannabidiol (CBD) affects the brain and body's response to stress. Researchers will examine 160 young adults who experienced childhood adversity, giving them either CBD or a placebo. The study measures brain activity, stress hormones, and anxiety…

This study aims to test a simple method for understanding the daily lives of breast cancer survivors. Researchers want to see if a 14-day mobile phone diary is a practical way to track daily stress and thinking patterns. They will recruit 30 diverse survivors who are at least fiv…

This study looks at how searching for health information online affects stress and emotional well-being in women undergoing infertility treatment. Researchers will survey 201 women about their internet search habits, stress levels, and overall well-being during treatment. The goa…

This study aims to understand how negative feelings like stress, pain, and hunger affect the brain and change the way people make decisions. Researchers will recruit 900 healthy adults and temporarily induce these states using methods like watching videos, solving math problems, …

This study aims to understand why people respond to stress differently by looking at brain activity. Researchers will scan the brains of 68 healthy volunteers twice while they perform stressful tasks, measuring how the brain uses energy and how its regions communicate. The goal i…

This study is investigating whether eating a daily mix of nuts for six months can improve mental health, reduce stress, and enhance thinking skills in young adults. It will involve 135 university students aged 18-25 who will be randomly assigned to either eat nuts or not. Researc…

This study aims to understand why women going through menopause who experience depression may have a higher risk of developing heart disease. Researchers will enroll 30 women to measure their body's stress responses during a brief social stress test. The goal is to gather knowled…

This study aims to understand the connection between daily lifestyle choices and heart health. Researchers will enroll 100 adults and young people to complete questionnaires about their physical activity, diet, stress, and sleep. They will then compare these answers to the partic…

This study aims to understand how a mother's stress and life experiences might affect tiny energy centers in her cells (mitochondria) and inflammation, potentially increasing the risk of preterm birth. Researchers will follow 180 pregnant women to see if different stress profiles…

This study aims to understand how supporting mothers of hospitalized infants affects family wellbeing. Researchers will connect mothers experiencing depression, anxiety, or food insecurity with helpful resources and emotional support. They want to see if this assistance improves …

This study aims to understand how adding chia seeds to your diet affects the community of bacteria in your gut (the microbiome) and relates to stress. For 16 weeks, 60 healthy adults will either add a daily serving of chia seeds to their diet or maintain their normal diet, while …

This study aims to understand how stress affects a person's response to opioid pain medication and their risk of misusing it. Researchers will enroll 120 adults with chronic back pain to measure their stress levels and then test their pain relief and feelings about the drug oxyco…

This early-stage study aims to understand if the compound CBD (cannabidiol) can help people who smoke cigarettes better manage stress and the cravings that come with nicotine withdrawal. Researchers at Johns Hopkins will give 90 daily smokers different doses of CBD or a placebo, …

This study aims to understand how a brief, full-body cold-water bath affects a person's choices, stress levels, and body signals. Forty healthy adults will take one cold bath and one warm bath about a month apart, while researchers measure their decisions in games, food preferenc…

This study aims to understand how stressful childhood experiences affect heart and blood vessel health later in life. Researchers will measure heart function, blood vessel health, and lung capacity in 120 young people aged 9-30. The goal is to learn how early stress might lead to…

This study is testing whether a simple mental health screening and support program can work for parents and caregivers of children with chronic illnesses. One hundred caregivers will complete a mental health questionnaire during their child's hospital appointment and receive info…