Stress test: scientists probe pain and hormones in HIV, cannabis, and depression

This study looks at how stress impacts pain, hormone levels, and mood in 120 people with and without HIV, cannabis use disorder, and depression. Participants will complete two sessions of a pain stress task and provide blood samples to measure cortisol and other stress hormones. The goal is to understand the links between stress, immune function, and these conditions, not to test a new treatment.