Cannabis dependence

This early-stage trial is testing whether low-intensity focused ultrasound (LIFU) can safely help people with opioid or other substance use disorders. The device sends sound waves to specific brain areas to calm cravings. 29 adults in outpatient treatment will receive both real a…

This study compares two patient navigation models for people recently involved in the criminal legal system who have substance use disorders. One group gets standard navigation, while the other can choose from a menu of services like in-person clinics, mobile health units, or tel…

This study tests whether a program called SBIRT (Screening, Brief Intervention, and Referral to Treatment) can help people reduce risky alcohol and drug use. About 400 adults visiting family planning clinics will either get SBIRT or usual care. Researchers will track changes in d…

This study tests whether full-spectrum or broad-spectrum CBD can help people with alcohol use disorder drink less. 180 adults who want to reduce or quit drinking will receive either CBD or a placebo for 12 weeks. Researchers will track changes in drinking habits, cravings, and an…

This study tests whether cannabidiol (CBD) can slow the progression of Alzheimer's disease in people aged 55-85 with mild cognitive impairment (early memory loss). Over 236 participants will receive either CBD or a placebo for a period, and researchers will measure changes in mem…

This study tests whether a common stop-smoking medication (varenicline) plus financial incentives can help adults aged 18-40 who use both e-cigarettes and cannabis quit vaping. All 105 participants will receive the drug and rewards for 12 weeks. Researchers will also track how ca…

This study tests whether hemp-derived CBD (with or without a tiny amount of THC) can help people who use cannabis concentrates regularly to cut down or stop. 165 adults who want to reduce their cannabis use will take either CBD or a placebo for 8 weeks, plus attend therapy. Resea…

This study tests whether a mobile app can help people in addiction treatment avoid relapse. 150 participants will either receive standard care or standard care plus the app, which monitors warning signs and sends alerts. The goal is to see if the app improves long-term recovery.

This study tests whether semaglutide (Wegovy), a drug used for weight loss, can help adults with cannabis use disorder use less cannabis. 100 participants will receive either semaglutide or a placebo injection weekly for 20 weeks. The main goal is to see if the drug reduces total…

This study tests whether a non-invasive brain stimulation technique called tDCS can reduce cannabis use in people with schizophrenia. 110 motivated participants will receive either real or sham stimulation over 5 days. Researchers will track changes in cannabis consumption, cravi…

This study looks at whether adding a six-session group recovery program and a 90-day home telehealth program can help veterans with substance use disorders drink less and use fewer drugs. About 195 veterans from a VA psychiatric unit will be randomly assigned to one of three grou…

This phase II trial tests whether adding a cannabis-based mouth spray (nabiximols) to standard chemotherapy helps people with recurrent glioblastoma live longer. About 120 adults whose brain tumor has returned after initial treatment will receive either the cannabis spray or a pl…

This study tests whether hemp-derived CBD can reduce the harmful effects of cannabis in young adults aged 18-25 who use cannabis at least five days a week but aren't looking to quit. Participants will take either CBD or a placebo for 8 weeks, and researchers will measure changes …

This study tests whether cannabidiol (CBD), a non-psychoactive compound from cannabis, can reduce cannabis concentrate use and cravings in people who use concentrates regularly but aren't trying to stop. 120 participants will take either 200 mg or 400 mg of CBD or a placebo daily…

This pilot study tests a personalized deep brain stimulation (DBS) method for people with severe, treatment-resistant substance use disorders. Ten participants will first undergo detox, then have temporary electrodes placed in their brains to map addiction-related circuits, follo…

This pilot study is testing whether a noninvasive brain stimulation device, used at home along with guided mindfulness, can help people with cannabis use disorder reduce their use. Forty-six adults who want to cut back on cannabis will receive either real or sham stimulation over…

This pilot study tests whether metformin, a diabetes drug, can help protect brain white matter in young adults (18-25) with early psychosis who use cannabis. Participants will take metformin for 6 months and undergo brain scans and questionnaires. The goal is to see if this appro…

This study tests whether varenicline (Chantix), a drug already used to help people quit smoking, can also help them reduce cannabis use. Two hundred adults in South Carolina who smoke cigarettes and use cannabis will receive either varenicline or a placebo, plus counseling. The g…

This study tests a new type of brain stimulation (rTMS) as a treatment for cannabis use disorder. Researchers will enroll 46 adults who use cannabis frequently and want to cut back or quit. The goal is to see if the treatment is safe, tolerable, and can reduce cravings and use.

This study looks at what happens when adults with cannabis use disorder cut back on cannabis. Over 8 weeks, participants get counseling, computer-based therapy, and small rewards for reducing use. The goal is to see if cutting back leads to fewer cannabis-related problems, better…

This pilot study at Johns Hopkins University is testing whether psilocybin, the active ingredient in magic mushrooms, can help people with cannabis use disorder. Twelve adults will receive two doses of psilocybin along with counseling over 12 weeks. Researchers will track cannabi…

This study tests a computerized task where teens push or pull a joystick in response to images, aiming to change automatic habits around cannabis and alcohol. Fifty-two participants aged 13-17 who use both substances will be followed for three months. The goal is to see if this s…

This study tests a new behavioral program called InTEGRA for teens aged 14-21 with alcohol or cannabis use disorder. It combines 12-step facilitation with motivational and cognitive-behavioral therapy. Researchers will compare it to standard therapy to see if it leads to more day…

This study tests a smartphone app designed to strengthen self-control in teens and young adults (ages 14-35) being treated for alcohol or cocaine use disorder. Participants will complete 12 short training sessions over about a month, plus booster sessions. The goal is to see if t…

This study is testing a smartphone app called MiREA-AC designed to help college students who have been mandated to reduce their alcohol and cannabis use. The app provides personalized feedback on their consumption and social norms. Researchers will enroll 150 students to see if t…

This study tests whether a non-invasive brain stimulation technique called TMS can help people with mental illness quit smoking. Forty daily smokers with psychiatric conditions will receive either TMS or standard care. The goal is to see if TMS is practical and effective in real-…

This study looks at how cannabis use and stress affect each other in young adults aged 18-25 with cannabis use disorder. Researchers will test whether a single dose of cannabidiol (CBD) can reduce withdrawal symptoms and stress, and delay the urge to use cannabis again. The goal …

This study tests whether trained peer recovery specialists can help Black individuals with substance use stick to their long-acting injectable HIV treatment or prevention. 186 participants will either get this peer support or standard care. The goal is to see if the peer program …

This study tests a brief computerized and smartphone-based program designed to help regular cannabis users with Cannabis Use Disorder better handle emotional stress. The goal is to see if the intervention reduces distress intolerance and cannabis use compared to a health educatio…

This study tests whether adding a trained family advocate to a proven parenting program can help prevent substance use and reduce childhood trauma. About 360 families from 36 high-risk communities in New Jersey will take part. The goal is to see if extra support makes the program…

This study tests a smartphone-based program called RISE Guide for women who have just been sexually assaulted. The goal is to see if it can reduce anxiety sensitivity and prevent posttraumatic stress disorder (PTSD) and cannabis use disorder (CUD). 68 women who seek emergency car…

This study tests a new medication called PP-01 to help adults with cannabis use disorder manage withdrawal symptoms when they stop using cannabis. About 420 participants will receive PP-01, an existing drug (nabilone), or a placebo daily for 34 days, with a one-week hospital stay…

This Canadian study is testing whether cannabinoid oils (CBD and THC) can safely help manage symptoms like pain in children aged 4-17 with relapsed or refractory cancer. The trial will enroll 60 kids across three hospitals, giving them different ratios of CBD to THC oils to see w…

This study tests a program called SKILLS that focuses on common factors across different mental health conditions, rather than treating each disorder separately. About 60 adults with stable psychiatric diagnoses will take part. The goal is to see if this approach reduces symptoms…

This study tests four virtual coaching sessions to help veterans with chronic pain use their own cannabis products more effectively. Researchers aim to see if coaching improves pain, anxiety, and overall well-being. The trial is recruiting 468 veterans across the U.S.

This study tests a smartphone app called AMP-C that teaches people to notice and enjoy positive events. The goal is to see if it can reduce depression and cannabis use in adults who struggle with both. Eighty participants will either use the app or just track their symptoms. The …

This study tests whether a type of talk therapy for insomnia, delivered via telemedicine, can improve sleep and reduce cannabis use in adults who have trouble sleeping and use cannabis regularly. 200 participants will be randomly assigned to either cognitive behavioral therapy fo…

This study tests whether IGC-AD1, a THC-based oral medication, can safely reduce agitation in people with mild to severe Alzheimer's dementia. About 164 participants will receive either the drug or a placebo twice daily for several weeks. Researchers will measure changes in agita…

This study is testing whether music therapy can help people with substance use disorder. 600 participants across Europe will be randomly assigned to either active music-making, music listening, or standard treatment. The goal is to see if music therapy improves addiction severity…

This study tests whether a natural hormone called pregnenolone can reverse the effects of cannabis intoxication. Researchers at Johns Hopkins will give 20 healthy adults who have used cannabis before either pregnenolone or a placebo, then measure changes in drug effects, thinking…

This study tests whether dronabinol, a synthetic form of THC (the psychoactive compound in cannabis), can reduce severe breathlessness in people with advanced COPD. Thirty participants will receive both dronabinol and a placebo in random order to compare effects. The goal is to s…

This study compares two brief behavioral interventions for emerging adults aged 18-25 who use cannabis frequently (at least 20 days per month). Participants attend two 40-50 minute sessions a week apart and are followed for 6 months. The goal is to see if either program helps red…

This study tests a brief, virtual cognitive remediation therapy (Action-Based Cognitive Remediation) for young people aged 16-30 with early psychosis who also misuse alcohol or cannabis. The therapy aims to improve thinking skills and reduce substance use. Researchers will enroll…

This study tests if a marijuana-based drug (mostly CBD with a little THC) can reduce anxiety in adults with autism. About 108 people aged 18 to 45 will take the drug or a placebo daily for 8 weeks. Researchers will track anxiety, social skills, and repetitive behaviors through we…

This study is testing whether a virtual reality version of a therapy exercise is practical and helpful for adults (ages 18-65) with psychiatric disorders. Participants will try one VR session and answer questions about their experience. The goal is to see if this approach is acce…

This study is testing whether 12 weeks of group cognitive behavioral therapy (CBT) can help people reduce their alcohol or cannabis use. Researchers will enroll 400 adults with alcohol use disorder or cannabis use disorder. Participants will attend weekly CBT sessions, and the st…

This study is testing a type of talk therapy called Emotion Regulation Therapy (ERT) delivered over video for people in New York who struggle with worry, overthinking, or being hard on themselves. The goal is to see if the therapy helps people better manage their emotions and fee…

This study tests whether a brief motivational interviewing session during a primary care visit can reduce alcohol and cannabis use among diverse teens aged 12 to 17. Researchers will enroll 500 participants who are at risk for substance use and track changes in how often they dri…

This study looks at how well and how safely a new sleep medication, lemborexant, works for people who have both a mental health condition and trouble sleeping. About 121 adults will take the drug for 8 weeks, and researchers will track changes in their sleep quality and any side …

This study tests whether cannabidiol (CBD), a non-intoxicating compound from cannabis, can reduce inflammation in the brain. Researchers will give CBD or a placebo to 80 adults with chronic low back pain, with or without mild-to-moderate depression. They will use brain scans to m…

This study tests whether nabilone, a synthetic cannabinoid, can safely reduce agitation in people with Alzheimer's disease. Agitation is common and distressing, with few good treatment options. About 112 participants will receive either nabilone or a placebo for 8 weeks, and rese…

This study tests a multi-sensory therapy called Heal, which uses calming sounds, gentle vibrations, and soft lighting to help detained youth (ages 12-18) manage their emotions before counseling sessions. The goal is to see if this brief, non-verbal intervention improves emotional…

This study tests whether sailing can help people with psychiatric disorders feel better. Forty adults in France will either take sailing lessons or continue their usual care. Researchers will measure changes in quality of life, mental well-being, and self-esteem to see if sailing…

This study tests whether peer support workers—people with lived experience of substance use—can help people who use drugs feel safer and stay in the emergency department until their care is complete. The study will compare what happens when peer workers are on shift versus when t…

This study tests whether a single dose of cannabis oil can reduce acute radicular (nerve-related) back pain and the need for opioid painkillers. Two hundred adults with sudden back pain will receive either cannabis oil or a placebo (olive oil) and be monitored for 24 hours. The g…

This pilot study tests whether screening and treating sleep disorders during tobacco or cannabis cessation therapy helps people stay abstinent longer. 80 participants will either get usual care or extra sleep-focused care. The study follows them for 6 months to see if addressing …

This early-phase trial is testing whether a generative AI chatbot called Therabot-CALM is usable and acceptable for people with cannabis use disorder who also have anxiety or depression. Fifteen participants will use the app for 4 weeks and give feedback through interviews and su…

This study aims to create a large data repository by collecting smartphone data and daily surveys from 10,000 adults who use alcohol or drugs. Participants will use an app that tracks phone activity and location, and answer short surveys about mood and substance use. The goal is …

This study investigates how THC and CBD in cannabis affect recognition memory in healthy adults who use cannabis regularly. Participants perform a memory task after smoking cannabis and on a separate sober day, while their brain activity is recorded via EEG. Blood samples measure…

This study is testing whether simple saliva tests done at home can accurately show when someone has not used cannabis. Researchers will enroll 200 people aged 18-30 who use cannabis at least once a week. Participants will provide saliva and urine samples over 3-4 weeks, and resea…

This study investigates how depression and cannabis use together affect brain circuits involved in reward and pain in young people living with HIV. Researchers will use MRI scans and questionnaires to measure brain activity, mood, and substance use. The goal is to understand why …

This study looks at whether brain activity related to learning can predict how well teens respond to a program aimed at reducing cannabis use. Teens aged 14-17 get a brain scan, then attend 10 weekly virtual sessions where they report use and take drug tests. They can earn prizes…

This study looks at how THC and CBD, two compounds found in cannabis, affect the body's stress response in people who are sleep-deprived and have higher-than-average anxiety. Sixty healthy volunteers will take either THC, CBD, both, or a placebo after a night of restricted sleep.…

This study compares two ways to help adults with mental health issues get follow-up care. One group gets usual care after an emergency room visit, while the other uses a new system that books a psychiatrist appointment within 48 hours through their general doctor. Researchers wil…

This early-phase study is looking at how cannabidiol (CBD) affects the appeal and pain-relieving effects of cannabis. Researchers will give 23 healthy adults different doses of CBD for 14 days and then measure how much they like active cannabis and how it changes their pain sensi…

This study looks at young adults aged 18 to 25 who use both tobacco/nicotine products and cannabis. Researchers want to understand what happens to cannabis use when participants try to quit nicotine. All participants receive remote counseling and incentives to stop using nicotine…

This study looks at whether regular cannabis users can adjust how much they vape when using high-potency concentrates (30%, 60%, and 90% THC). Researchers will measure blood THC levels, puffing behavior, and subjective feelings of intoxication. The goal is to understand if people…

This study looks at the mental health of 200 teenagers aged 12 to 16 who attend special educational institutes (ITEPs) in France. Researchers will use psychiatric interviews to find out how many have conditions like depression or anxiety. The goal is to better understand their ne…

This study aims to improve suicide prevention for people who move between healthcare and the criminal-legal system. Researchers will link health records, Medicaid data, and jail booking information to identify individuals at risk and coordinate care. Over 1,000 adults with past p…

This study looks at how inhaled cannabis affects the brain in people with chronic low back pain. Researchers will use MRI scans to measure changes in brain blood flow and oxygen levels, and ask participants to rate their pain. The goal is to understand the brain mechanisms behind…

This study looks at how stopping cannabis use for 28 days changes brain activity and memory in people with psychosis and in cannabis users without psychosis. Participants are randomly assigned to either quit cannabis or continue using, and undergo brain scans before and after the…

This study looks at how stopping smoking for six weeks affects the body's chemistry and gut bacteria in people being treated for substance use disorders. Researchers will compare 100 participants who quit smoking with 50 healthy controls, using blood and stool samples along with …

This study looks at how a single session of exercise changes blood markers related to brain health in people who use cannabis regularly compared to those who don't. Researchers will measure endocannabinoids and other substances in the blood, along with cognitive tests. The goal i…

This study tests whether combining neurofeedback with integrative body-mind training can change brain function and reduce cravings and substance use in adults who regularly use alcohol, cannabis, and cigarettes. Researchers will use brain scans to measure changes in connectivity …

This study tests whether a non-invasive brain stimulation technique called TMS can change how people with severe cannabis use disorder recognize their cannabis-related problems. Twenty-four participants will receive real and sham TMS while researchers measure brain activity and e…

This study looks at how men and women with cannabis use disorder react differently to THC, the main psychoactive ingredient in cannabis. Researchers will give 40 adults either a THC pill or a placebo and use brain scans to measure changes in reward-related brain activity. The goa…

This study is investigating how common cannabis use is among lung cancer patients under 60 and whether it is linked to more aggressive tumors. Researchers will collect blood and hair samples from 150 participants across three French hospitals. The goal is to better understand if …

This study aims to see if a digital version of the WHO's mental health guide for substance use disorders can be used effectively in primary care settings in Pakistan. Researchers will train 300 primary care doctors in three major cities using this digital tool. The goal is to und…

This study looks at how CBD and THC, two compounds found in cannabis, affect inflammation and brain health in people with HIV. About 90 participants will take both substances in a random order over six weeks. Researchers will measure blood markers and brain function to better und…

This study looks at how cannabis ingredients (THC and CBD) affect decision-making, attention, and motivation in people with and without HIV. About 138 adults who use cannabis infrequently will take either THC, CBD, or a placebo for 5 days and complete thinking tests and brain flu…

This study uses a special PET scan tracer called [11-C]OMAR to measure cannabinoid receptors in the brain. Researchers will compare healthy volunteers to people with schizophrenia, cannabis dependence, PTSD, opioid use disorder, and other conditions. The goal is to understand how…

This study looks at how stress impacts pain, hormone levels, and mood in 120 people with and without HIV, cannabis use disorder, and depression. Participants will complete two sessions of a pain stress task and provide blood samples to measure cortisol and other stress hormones. …

This study looks at how the active ingredient in cannabis, THC, affects men and women differently. Researchers will give THC to 100 healthy adults who have used cannabis before and measure their feelings of being 'high' and memory performance. The goal is to understand why men an…

This study looks at how THC, the active part of cannabis, changes people's desire for e-cigarettes and their body's response. Researchers will give different doses of THC to 100 adults who use both e-cigarettes and cannabis, then measure how much they vape, their cravings, heart …

This study looks at how the brains of teens (ages 15-18) with cannabis use disorder change when they stop using cannabis for 6 weeks. Researchers will use MRI scans to measure brain activity related to reward and impulse control. Some teens will be paid to stay cannabis-free, whi…

This study looks at how cannabis use and stopping it affect sleep, daily body rhythms, and sensitivity to light in healthy young adults aged 18-25. Researchers will compare regular cannabis users with non-users using sleep monitors, light tests, and pupil measurements. The goal i…

This study looks at how chronic marijuana use changes brain inflammation and thinking abilities in people with HIV. Researchers will use brain scans and blood tests to measure brain health in 220 adults. The goal is to understand the effects, not to test a new treatment.

This study looks at how age and how often someone uses cannabis affect driving skills. Researchers will compare young (19-25) and middle-aged (35-45) drivers who use cannabis occasionally or frequently. Participants will smoke a cannabis cigarette or a placebo and then drive in a…

This study aims to understand if cannabis affects pain relief and the risk of abuse differently in men and women. Researchers will give 160 regular cannabis users either active cannabis or a placebo and measure their pain response, drug effects, and blood levels. The goal is to g…

This study looks at whether a program with a nurse case manager can help people leaving prison visit a doctor or clinic instead of the emergency room. About 488 adults with a history of substance use and a chronic health condition will take part. Some will get extra support from …

This study looks at brain changes in people who use cannabis heavily and want to quit. Researchers will use brain scans to measure a protein linked to brain cell connections, both before and after at least 4 weeks of not using cannabis. They will also test memory to see if brain …

This study looks at whether using a special counseling style called Motivational Interviewing during the first visit can help people stay in addiction treatment. Researchers will compare this approach to the usual intake process. About 150 adults seeking outpatient addiction trea…

This study looks at whether a tool called MyPath helps women with substance use disorder make better decisions about birth control after having a baby. About 400 women will use the tool during pregnancy or right after delivery. The goal is to see if it helps them pick a method th…

This study looks at how natural changes in female sex hormones during the menstrual cycle affect the way women feel and think after using cannabis. Researchers will give 21 women a set dose of THC (the active part of cannabis) or a placebo at different points in their cycle. They…

This study tests whether a brief online video about cannabis withdrawal can increase awareness and insight in people who use cannabis daily. Researchers will recruit 100 heavy users (at least 25 days per month and 3.5 grams per week) through an online platform. Participants will …

This study uses a special brain scan (PET) to measure the density of connections between brain cells in people with psychotic disorders (like schizophrenia) or cannabis use disorder, compared to healthy volunteers. The goal is to understand how brain connection changes relate to …

This study looks at how THC, the active part of cannabis, affects cigarette cravings and smoking habits. Researchers will give 100 adults who smoke both tobacco and cannabis different doses of THC or a placebo, then measure how many cigarette puffs they take and how they feel. Th…

This study looks at how oral THC (the main psychoactive ingredient in cannabis) affects driving performance, both alone and with alcohol. 48 healthy adults aged 21-55 will use a driving simulator after taking different doses of THC with or without alcohol. The goal is to understa…

This study looks at how age and sex influence the effects of THC, the main psychoactive ingredient in cannabis. Researchers will give smoked and oral THC to 103 adults aged 18-65 who use cannabis regularly. They will measure pain relief, intoxication, impairment, and how the body…

This study looks at what happens when people who regularly use both marijuana and tobacco use them together. Researchers will measure how much THC and nicotine get into the blood and how the body responds. The goal is to better understand the health effects of using both substanc…

This study works with Black teens on probation and their families to adapt alcohol and drug treatment to better address experiences of racial discrimination. Researchers will interview teens and hold focus groups with parents and community advocates to learn what works. The goal …

This study is looking at 120 people who are already in treatment for abusing opioids and/or benzodiazepines (anti-anxiety drugs). Researchers want to understand why people use these drugs together, which greatly raises the risk of overdose and death. Participants will complete in…

This study follows up to 10,000 medical students in Orléans, France, for up to 22 years to understand what puts them at risk for depression and other mental health issues. Participants fill out an annual online questionnaire. The goal is to identify early warning signs so that fu…

This pilot study compares regular cannabis users to non-users to find biomarkers that can estimate when someone last inhaled cannabis. Researchers will measure chemicals in blood and look at genetic factors. The goal is to improve road safety by developing a more accurate test fo…

This study is testing whether different doses of cannabidiol (CBD) can reduce the psychoactive effects of THC in healthy adults who use cannabis occasionally. One hundred participants will inhale various combinations of CBD and THC and report their experiences. The goal is to fin…

This study looks at how CBD (a non-psychoactive cannabis compound) changes the effects of THC (the compound that makes you high). Researchers will give both substances to 30 regular cannabis users who are not seeking treatment. They want to see if CBD can reduce the abuse potenti…

This study aims to develop and test a supervision strategy for clinical supervisors in substance use disorder treatment programs. The goal is to reduce counselor burnout and turnover, and improve their well-being and performance. About 43 supervisors and counselors from residenti…

This study is testing a cooking and nutrition program for 50 people in Texas who are recovering from opioid use and living in recovery homes while on medication therapy. The program aims to improve their eating habits and confidence in cooking skills. Participants will fill out q…

This study is following 10,000 people who are seeking help for substance or behavioral addictions. Researchers will track their medical, brain, social, and psychological health over several years using interviews, questionnaires, and cognitive tests. The goal is to better underst…

This registry study is collecting real-world data from 1,000 adults with cancer who use cannabis. Participants use an app to track symptoms, cannabis use, and changes in other medications. The goal is to help patients and doctors make informed decisions about using cannabis for s…

This study follows 600 black and white adults with solid tumor cancer who use cannabis at least weekly or not at all. Participants report pain, symptoms, and cannabis use through a smartphone app and surveys for one year. The goal is to understand how cannabis affects pain and op…

This study looks at how smoking high-potency cannabis affects pain relief, feelings of being high, and drug levels in the blood. Researchers will test 30 near-daily cannabis users who are not seeking treatment. Participants will smoke either placebo, low-dose, or high-dose THC ca…

This study looks at whether having a specially trained peer recovery specialist in the emergency department helps people with substance use disorders connect to treatment and support services. Researchers will follow 400 adults who visit the ER for substance-related issues, compa…

This study is creating a program called START-VET to help veterans with mental illness or substance use disorders who have recently left prison. Researchers will work with 20 veterans to develop transition materials and tools. The goal is to improve quality of life and reduce cri…

This study looks at whether teens aged 15-18 who stop using cannabis for 8 weeks show improvements in thinking skills like memory, attention, and planning. Researchers will test 29 teens with cannabis dependence using brain games and urine tests. The goal is to see if abstinence …

This study gives people with Cannabis Use Disorder drugs that mimic stress to see how it affects their desire for cannabis. Researchers measure brain activity and decision-making during four lab visits. The goal is to understand the link between stress and cannabis use motivation…

This pilot study is testing whether a simple saliva test can help doctors prescribe mental health medications more safely and effectively. 200 adults in Manitoba who are starting or changing psychiatric drugs will provide a DNA sample. The results will be shared with their doctor…

This study looks at whether training psychiatric care teams to talk about sexual health with young patients (ages 15 and up) increases those conversations. Researchers will survey 770 teens hospitalized for psychiatric disorders about their sexual health and any side effects from…