Can a single dose of cannabis oil ease acute back pain?

NCT ID NCT04816994

Recruiting now Symptom relief Sponsor: Hadassah Medical Organization Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a single dose of cannabis oil can reduce acute radicular (nerve-related) back pain and the need for opioid painkillers. Two hundred adults with sudden back pain will receive either cannabis oil or a placebo (olive oil) and be monitored for 24 hours. The goal is to see if cannabis oil provides safe and effective pain relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cannabis oil (containing THC and CBD)
What this could lead to: If it works, this could offer a new, fast-acting option for managing sudden nerve-related back pain and reducing reliance on opioids.
What could go wrong: This is a single-dose, 24-hour study, so long-term effects and benefits are unknown. The results may not apply to chronic pain or regular cannabis users.

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Conditions

The condition(s) this trial relates to.

cannabis dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE RADICULAR BACK PAIN CANNABIS

Contacts and locations

Locations

Hadassah Medical Center
RECRUITING

Jerusalem, Israel

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