Hadassah Medical Organization

This early-phase trial is testing a new treatment called HBI0101 CAR-T for people with multiple myeloma that has come back or stopped responding to standard therapies. The treatment involves taking a patient's own immune cells, modifying them in a lab to better recognize and atta…

This study tests a vaccine made from modified melanoma cells in patients who had their tumors removed but are at high risk of recurrence. The vaccine is designed to train the immune system to recognize and attack any remaining cancer cells. Up to 50 participants will receive mult…

This study looks at whether a moderate carbohydrate diet (up to 120g per day) can help pregnant women with diabetes who need insulin achieve better blood sugar control compared to the standard high-carb diet. The trial will include 120 pregnant women and track their glucose level…

This early-phase trial tests a personalized vaccine made from a patient's own tumor cells or donor cells. The cells are modified and killed in the lab, then injected under the skin to train the immune system to attack the cancer. The study includes 50 adults with metastatic melan…

This early-phase study tests a personalized cell therapy for people with several types of advanced cancer that have spread and express a protein called NY-ESO-1. Participants receive a single infusion of their own immune cells that have been genetically modified to recognize and …

This study tests whether one dose of zoledronic acid can prevent bone loss that often happens when people start HIV medications. About 110 adults newly diagnosed with HIV and showing early bone thinning will be randomly assigned to get the drug or just follow-up. Researchers will…

This study tests a remote group program called CRAFT-G for breast cancer survivors who struggle with thinking and memory problems after treatment. The program includes six online group sessions led by an occupational therapist, plus computer-based brain training three times a wee…

This study tests if watching relaxing virtual reality (VR) scenes before an egg retrieval procedure can lower pain. One hundred women having elective egg freezing will either get standard care or standard care plus a VR relaxation session. Pain levels are measured with a simple 0…

This study tests whether a single dose of cannabis oil can reduce acute radicular (nerve-related) back pain and the need for opioid painkillers. Two hundred adults with sudden back pain will receive either cannabis oil or a placebo (olive oil) and be monitored for 24 hours. The g…

This trial is testing a software dashboard that uses artificial intelligence to continuously estimate a woman's risk of needing an unplanned C-section during labor. The study involves 400 first-time mothers with a single baby in head-down position. Half of the participants will h…

This study looks at how genetic differences in the CYP2C9 enzyme affect the way healthy volunteers process warfarin and similar drugs. Researchers will give participants single doses of one or more of these drugs and measure how their bodies break them down. The goal is to better…

This early-stage study will give 10 healthy adults a single dose of psilocybin (the active ingredient in magic mushrooms) combined with D-serine, an amino acid. Researchers want to see if D-serine can tone down the psychedelic effects and improve safety. The goal is to find the r…