Experimental vaccine trains body to fight advanced cancers
NCT ID NCT00722228
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This early-phase trial tests a personalized vaccine made from a patient's own tumor cells or donor cells. The cells are modified and killed in the lab, then injected under the skin to train the immune system to attack the cancer. The study includes 50 adults with metastatic melanoma, breast, ovarian, colorectal, gastric, lung, or kidney cancer who have already tried chemotherapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- personalized whole-cell cancer vaccine (irradiated, DNP-conjugated tumor cells)
- What this could lead to
- If it works, this could offer a new way to stimulate the immune system against advanced cancers, potentially prolonging survival in patients who have run out of options.
- What could go wrong
- This is an early-phase (1/2) trial with only 50 participants, so results may not apply broadly. The vaccine may not boost immunity enough to shrink tumors or extend life, and side effects from immune activation are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hadassah Medical Organization
RECRUITINGJerusalem, 91120, Israel
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