Experimental vaccine trains body to fight advanced cancers

NCT ID NCT00722228

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This early-phase trial tests a personalized vaccine made from a patient's own tumor cells or donor cells. The cells are modified and killed in the lab, then injected under the skin to train the immune system to attack the cancer. The study includes 50 adults with metastatic melanoma, breast, ovarian, colorectal, gastric, lung, or kidney cancer who have already tried chemotherapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

personalized whole-cell cancer vaccine (irradiated, DNP-conjugated tumor cells)

What this could lead to

If it works, this could offer a new way to stimulate the immune system against advanced cancers, potentially prolonging survival in patients who have run out of options.

What could go wrong

This is an early-phase (1/2) trial with only 50 participants, so results may not apply broadly. The vaccine may not boost immunity enough to shrink tumors or extend life, and side effects from immune activation are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm colorectal cancer colorectal neoplasm gastric cancer gastric carcinoma gastric neoplasm kidney cancer lung cancer lung carcinoma lung neoplasm melanoma metastatic melanoma ovarian cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hadassah Medical Organization

    RECRUITING

    Jerusalem, 91120, Israel

    Contact