A new breathing test may catch a deadly transplant complication earlier than ever

NCT ID NCT07730931

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This study tests whether a non-invasive breathing test called Forced Oscillation Technique (FOT) can detect bronchiolitis obliterans syndrome (BOS) — a serious lung condition — earlier than standard tests in people who have received a bone marrow transplant. Researchers will compare FOT results with usual lung function tests in 400 children and adults. The goal is to see if FOT can improve diagnosis, monitoring, and treatment assessment for this complication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Forced Oscillation Technique (FOT) — a non-invasive breathing test
What this could lead to
If FOT proves accurate, it could enable earlier detection of a serious lung complication after bone marrow transplant, potentially improving outcomes.
What could go wrong
This is an early diagnostic study, not a treatment trial. FOT may not prove more useful than standard tests, and results may not apply to all transplant centers.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hadassah MO, Jerusalem, 9574869, Jerusalem,

    RECRUITING

    Jerusalem, Israel

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