Scientists smoke out cannabis effects in new study

NCT ID NCT06859723

Recruiting now Knowledge-focused Sponsor: University of California, Los Angeles Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how smoking high-potency cannabis affects pain relief, feelings of being high, and drug levels in the blood. Researchers will test 30 near-daily cannabis users who are not seeking treatment. Participants will smoke either placebo, low-dose, or high-dose THC cannabis, both during normal use and after a short break from cannabis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cannabis (smoked)
What this could lead to: If successful, this could help understand how high-potency cannabis affects pain and abuse potential, informing safer use guidelines.
What could go wrong: This is a small, early-phase study with only 30 participants, so results may not apply broadly. It does not test a treatment or cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cannabis dependence Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ABUSE CANNABIS PAIN PHARMACOKINETICS

Contacts and locations

Locations

UCLA Center for Cannabis and Cannabinoids
RECRUITING

Los Angeles, California, 90095, United States

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