Electric pulses on the wrist may tame colonoscopy pain
NCT ID NCT06813703
First seen Aug 14, 2026 · Last updated Aug 14, 2026
Summary
This trial tests whether a mild electrical stimulation device, applied near the wrist and ankle, can reduce pain during a colonoscopy performed without sedation. Sixty adults aged 18 to 75 will be randomly assigned to receive either real stimulation or a sham version. While the procedure happens, researchers will monitor brain activity using EEG and infrared sensors to see how the stimulation affects pain-related brain regions. The goal is to understand if this technique offers a safe, non-drug way to make unsedated colonoscopy more comfortable.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Transcutaneous electrical nerve stimulation (TENS) based on wrist-ankle acupuncture theory
- What this could lead to
- If it works, this could offer a drug-free way to reduce pain during colonoscopy without sedation, making the procedure more comfortable for patients.
- What could go wrong
- This is a small, early-stage trial, so results may not apply broadly. The sham control uses minimal stimulation, and pain relief may be modest or vary between individuals.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The First Affiliated Hospital of Naval Medical University
Shanghai, Shanghai Municipality, 200433, China
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