Can a pill and cash help dual users of E-Cigs and pot quit vaping?

NCT ID NCT06688539

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a common stop-smoking medication (varenicline) plus financial incentives can help adults aged 18-40 who use both e-cigarettes and cannabis quit vaping. All 105 participants will receive the drug and rewards for 12 weeks. Researchers will also track how cannabis use changes during the quit attempt.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

varenicline (a stop-smoking medication) and financial incentives

What this could lead to

If successful, this could provide an effective treatment for quitting e-cigarettes in people who also use cannabis, a group often excluded from cessation studies.

What could go wrong

This is a small Phase 4 trial with only 105 participants and no placebo group, so results may not apply broadly. Varenicline can cause side effects like nausea and sleep disturbances.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cannabis dependence nicotine dependence Vaping

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Behavioral Health Services of Pickens County

    RECRUITING

    Pickens, South Carolina, 29671, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • MUSC Charleston

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • MUSC Lancaster

    RECRUITING

    Lancaster, South Carolina, 29720, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••