Nicotine dependence
MONDO:0008575Physical and psychological dependence on nicotine.
Also known as: nicotine addiction, tobacco use disorder
465 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Can cash incentives and a quit-smoking pill curb both drinking and smoking?
Disease control Recruiting nowThis study tests whether combining varenicline (a medication that helps people stop smoking) with financial rewards for clean urine samples can reduce alcohol and tobacco use in adults who both drink heavily and smoke daily. Participants are randomly assigned to receive either re…
Phase: PHASE2 • Sponsor: Washington State University • Aim: Disease control
Last updated Jul 03, 2026 23:00 UTC
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Could a psychedelic compound help smokers quit for good?
Disease control Recruiting nowThis study tests whether psilocybin, a psychedelic substance, can help people stop smoking. Sixty-six daily smokers who have tried and failed to quit before will receive either psilocybin or niacin (a vitamin) in two sessions one week apart. Researchers will check if participants…
Phase: PHASE2 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Texts and patches aim to help HIV patients kick the habit
Disease control Recruiting nowThis study tests a program that sends personalized text messages and provides nicotine patches to help people with HIV in Cambodia stop smoking. Researchers will enroll 800 smokers and check if they quit after 6 months using self-reports and breath tests. The goal is to find a pr…
Phase: NA • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Could sound waves help fight addiction? new trial explores ultrasound for opioid use
Disease control Recruiting nowThis early-stage trial is testing whether low-intensity focused ultrasound (LIFU) can safely help people with opioid or other substance use disorders. The device sends sound waves to specific brain areas to calm cravings. 29 adults in outpatient treatment will receive both real a…
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Choice over standard care may boost HIV treatment in Justice-Involved groups
Disease control Recruiting nowThis study compares two patient navigation models for people recently involved in the criminal legal system who have substance use disorders. One group gets standard navigation, while the other can choose from a menu of services like in-person clinics, mobile health units, or tel…
Phase: NA • Sponsor: Yale University • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Sound waves in the brain: a new hope for smokers?
Disease control Recruiting nowThis study tests a new, non-invasive treatment using low-intensity focused ultrasound (LIFU) to help people quit smoking. It targets deep brain areas linked to nicotine addiction without surgery or needles. The study will enroll 100 adults who have smoked for at least 5 years and…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Can a zap to the neck help smokers quit? new trial tests nerve stimulator
Disease control Recruiting nowThis study tests whether a handheld device that gently stimulates the vagus nerve in the neck, combined with a nicotine patch, can help people stop smoking. Researchers at Mayo Clinic will enroll 150 motivated smokers who smoke at least 10 cigarettes a day. Participants use the d…
Phase: PHASE2, PHASE3 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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App and coach team up to help women kick the habit
Disease control Recruiting nowThis study tests a program that combines community health worker visits with a smartphone app to help low-income women stop smoking. About 344 women in Brazil will either get the app plus health worker support or just a referral to a standard quit-smoking clinic. The goal is to s…
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Can nicotine patches and lozenges help rural smokers kick the habit?
Disease control Recruiting nowThis study is testing whether giving rural smokers a two-week supply of nicotine patches or lozenges can help them quit. Researchers are recruiting 272 adults from rural areas across the U.S. who smoke at least 5 cigarettes daily. The main goal is to see how many people stop usin…
Phase: NA • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Can a quick chat in a family planning clinic curb risky drinking and drug use?
Disease control Recruiting nowThis study tests whether a program called SBIRT (Screening, Brief Intervention, and Referral to Treatment) can help people reduce risky alcohol and drug use. About 400 adults visiting family planning clinics will either get SBIRT or usual care. Researchers will track changes in d…
Phase: NA • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Can a pill and cash help dual users of E-Cigs and pot quit vaping?
Disease control Recruiting nowThis study tests whether a common stop-smoking medication (varenicline) plus financial incentives can help adults aged 18-40 who use both e-cigarettes and cannabis quit vaping. All 105 participants will receive the drug and rewards for 12 weeks. Researchers will also track how ca…
Phase: PHASE4 • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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New study lets smokers choose their own path to quit
Disease control Recruiting nowThis study is for people who smoke cigarettes but aren't ready to quit. It tests whether giving them a choice of harm-reduction products like e-cigarettes or nicotine pouches helps them smoke less or stop altogether. Participants will use their chosen product for 28 days and be f…
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Yale study tests sleep fix to kick smoking habit
Disease control Recruiting nowThis study tests whether a behavioral sleep intervention combined with the drug varenicline can help heavy smokers quit. Researchers will measure sleep quality, smoking habits, and brain activity in 114 participants. The goal is to see if improving sleep reduces negative emotions…
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Flavor variety may boost quit rates in smokers switching to E-Cigs
Disease control Recruiting nowThis study tests whether giving smokers a choice of e-cigarette flavors (tobacco, menthol, mint, or other) helps them stop smoking regular cigarettes. About 1,280 adult smokers will use a provided e-cigarette device for 13 weeks, and researchers will check who stays away from cig…
Phase: NA • Sponsor: RAI Services Company • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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Phone calls to fight heart disease: new study tests coaching for young adults
Disease control Recruiting nowThis study tests whether a 12-week telephone health coaching program, called Support Your Heart, is practical and helpful for young adults aged 18-39 who have at least two heart disease risk factors (like poor sleep, inactivity, or high blood pressure). Twenty participants in the…
Phase: NA • Sponsor: George Washington University • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New study offers smokers with HIV free nicotine alternatives to kick the habit
Disease control Recruiting nowThis study tests whether offering a choice of e-cigarettes, nicotine pouches, or nicotine patches helps people with HIV stop smoking tobacco. About 972 participants in Switzerland will receive their preferred product free for 6 months, plus standard care. The main goal is to see …
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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E-Cigs vs. nicotine patches: which helps obese smokers kick the habit?
Disease control Recruiting nowThis study is testing whether e-cigarettes or nicotine replacement therapy (patches and lozenges) can help obese smokers quit or reduce smoking. Sixty participants will use one of the two products for 8 weeks, and researchers will track how many cigarettes they smoke, their carbo…
Phase: NA • Sponsor: Brown University • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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Can a phone app stop addiction relapse? new trial aims to find out
Disease control Recruiting nowThis study tests whether a mobile app can help people in addiction treatment avoid relapse. 150 participants will either receive standard care or standard care plus the app, which monitors warning signs and sends alerts. The goal is to see if the app improves long-term recovery.
Phase: NA • Sponsor: Clínica Nuestra Señora de la Paz • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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New program aims to help cancer survivors and caregivers quit tobacco together
Disease control Recruiting nowThis study is testing a tailored tobacco cessation program for cancer survivors and their caregivers. The program includes four sessions delivered by phone or video, focusing on quitting techniques and support. Researchers want to see how many people enroll and complete the progr…
Phase: NA • Sponsor: University of Florida • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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New program aims to help parents quit smoking and shield kids from secondhand smoke
Disease control Recruiting nowThis study tests a program that combines brief advice, nicotine replacement therapy (like patches or gum), and text-message support to help smoking parents quit. The goal is to reduce children's exposure to secondhand smoke. About 1,200 smoking parents in Hong Kong who live with …
Phase: NA • Sponsor: The University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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VA tests new combo therapy to help veterans beat addiction
Disease control Recruiting nowThis study looks at whether adding a six-session group recovery program and a 90-day home telehealth program can help veterans with substance use disorders drink less and use fewer drugs. About 195 veterans from a VA psychiatric unit will be randomly assigned to one of three grou…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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ERs test $300 quit card to kick smoking habit
Disease control Recruiting nowThis study tests a simple program for smokers visiting emergency rooms. Participants get a $300 gift card for nicotine replacement products, self-help materials, and six months of phone support from a specialist. The goal is to see if this approach helps more people quit smoking …
Phase: NA • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Money and smoking: new trial tests financial coaching to help quit
Disease control Recruiting nowThis study tests whether adding financial coaching to standard smoking cessation counseling helps low-income smokers quit. 602 participants will receive either standard counseling or integrated financial-smoking counseling, plus nicotine patches. The goal is to see if addressing …
Phase: PHASE3 • Sponsor: NYU Langone Health • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Brain zaps for addiction: new study targets relapse with personalized implants
Disease control Recruiting nowThis pilot study tests a personalized deep brain stimulation (DBS) method for people with severe, treatment-resistant substance use disorders. Ten participants will first undergo detox, then have temporary electrodes placed in their brains to map addiction-related circuits, follo…
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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New study tests mindfulness and motivation to help methadone patients kick multiple habits
Disease control Recruiting nowThis study is testing two counseling approaches—Motivational Interviewing (MI) and Mindfulness-Oriented Recovery Enhancement (MORE)—to help people on methadone treatment reduce their use of tobacco, opioids, and other drugs. Researchers will enroll 420 adults who are currently on…
Phase: PHASE3 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Brain zaps for smokers: new trial tests quick quit method
Disease control Recruiting nowThis study tests whether a 5-day course of accelerated deep transcranial magnetic stimulation (aTMS) can help adults aged 18–65 quit smoking. Participants receive 4 brain stimulation sessions per day for 5 days. The main goal is to see if the treatment is tolerable and practical,…
Phase: PHASE2 • Sponsor: Waypoint Centre for Mental Health Care • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New approach for HIV smokers: cut down, not quit
Disease control Recruiting nowThis study tests a harm reduction strategy for 400 people with HIV who smoke cigarettes. Instead of pushing for complete quitting, the program helps participants cut down on smoking, get screened for lung cancer, and manage blood pressure and cholesterol. The goal is to improve o…
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Brain training boosts Quit-Smoking success in new study
Disease control Recruiting nowThis study tests a new way to help people stop smoking by combining standard quit-smoking programs with a computer task that retrains unconscious urges to approach cigarettes. About 300 adults who want to quit will be randomly assigned to one of three groups: standard treatment p…
Phase: NA • Sponsor: University of Houston • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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CBD put to the test as a smoking reduction aid
Disease control Recruiting nowThis study tests whether cannabidiol (CBD), a compound from hemp, can help people who want to quit smoking reduce their cigarette use. 120 adults with tobacco use disorder will receive either CBD or a placebo twice daily for 56 days. Researchers will measure nicotine levels and c…
Phase: PHASE2 • Sponsor: University of California, Los Angeles • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New study aims to help HIV patients kick the habit for good
Disease control Recruiting nowThis study is testing a combination of counseling, peer mentoring, text messages, and nicotine replacement therapy to help people with HIV quit smoking. Researchers will enroll 500 smokers living with HIV in New York City to find the most effective and affordable approach. The go…
Phase: PHASE4 • Sponsor: New York University • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Singapore tests phone app to kick the habit
Disease control Recruiting nowThis study tests whether a mobile app can help adults in Singapore quit smoking. About 100 participants will be randomly assigned to receive the app-based support or standard care, and researchers will track how many stay smoke-free for 6 months. The goal is to see if this approa…
Phase: NA • Sponsor: National University of Singapore • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Can a Stop-Smoking drug also curb cannabis? new trial aims to find out
Disease control Recruiting nowThis study tests whether varenicline (Chantix), a drug already used to help people quit smoking, can also help them reduce cannabis use. Two hundred adults in South Carolina who smoke cigarettes and use cannabis will receive either varenicline or a placebo, plus counseling. The g…
Phase: PHASE3 • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Vapes vs. patches: new study tests if E-Cigarettes help smokers in recovery kick the habit
Disease control Recruiting nowThis study is testing whether e-cigarettes (nicotine vapes) can help people who are in treatment for substance use disorder quit smoking. Participants will either switch to e-cigarettes or use FDA-approved nicotine patches and lozenges, with weekly counseling. The goal is to see …
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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New study tests if menstrual cycle timing boosts Quit-Smoking success
Disease control Recruiting nowThis study tests whether starting nicotine replacement therapy (patches, gum, or lozenges) at a specific time in the menstrual cycle helps women quit smoking. About 1,200 women who smoke daily and have regular periods will be assigned to start their quit attempt during the follic…
Phase: PHASE4 • Sponsor: Centre for Addiction and Mental Health • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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New combo therapy aims to help bariatric patients drop weight and kick the habit before surgery
Disease control Recruiting nowThis early-stage study at Yale is testing whether a combination of two medications (naltrexone and bupropion) plus cognitive-behavioral therapy can help people who are considering bariatric surgery lose weight and stop smoking. Twenty participants will receive the treatment for f…
Phase: PHASE1 • Sponsor: Yale University • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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E-Cigs vs nicotine pouches: which helps smokers quit best?
Disease control Recruiting nowThis study tests whether e-cigarettes or nicotine pouches help adult smokers reduce their cigarette use. 256 participants who smoke will be given one of these products for 4 weeks, with different flavors and nicotine levels. Researchers will track how many cigarettes they smoke a…
Phase: NA • Sponsor: Yale University • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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New training aims to help smokers beat withdrawal and quit for good
Disease control Recruiting nowThis study tests a new program to help people quit smoking by teaching them how to handle withdrawal symptoms and negative feelings. Researchers will enroll 400 adult smokers who want to quit. The goal is to see if this training helps more people stay smoke-free compared to stand…
Phase: PHASE3 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Can a virtual pharmacy and coaching help smokers quit? new trial tests three options
Disease control Recruiting nowThis study compares three approved smoking cessation products—nicotine replacement therapy (patch plus gum or lozenge), cytisine, and varenicline—combined with coaching and home delivery from a virtual pharmacy. Researchers will track how well 150 Ontario adults who smoke use the…
Phase: PHASE4 • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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Can switching meds or using E-Cigs help smokers quit for good?
Disease control Recruiting nowThis study tests whether changing treatment can help smokers who relapse early after trying to quit. 544 participants who want to quit smoking will receive free nicotine patches, lozenges, varenicline, or e-cigarettes for 12 weeks. All visits are remote, and the study lasts 6 mon…
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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New therapy aims to boost teen recovery from substance use
Disease control Recruiting nowThis study tests a new behavioral program called InTEGRA for teens aged 14-21 with alcohol or cannabis use disorder. It combines 12-step facilitation with motivational and cognitive-behavioral therapy. Researchers will compare it to standard therapy to see if it leads to more day…
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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New study tests organized care for heart disease prevention
Disease control Recruiting nowThis study looks at whether a structured approach to managing heart disease risk factors (like high blood pressure, diabetes, and smoking) can improve health outcomes in adults. Researchers will follow 220 patients in a regular cardiology clinic, collecting data on their blood pr…
Phase: NA • Sponsor: Universidad Católica San Antonio de Murcia • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Can a phone app train young brains to resist alcohol and cocaine?
Disease control Recruiting nowThis study tests a smartphone app designed to strengthen self-control in teens and young adults (ages 14-35) being treated for alcohol or cocaine use disorder. Participants will complete 12 short training sessions over about a month, plus booster sessions. The goal is to see if t…
Phase: NA • Sponsor: University of Bern • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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New program aims to help smokers with mental illness kick the habit
Disease control Recruiting nowThis study tests a program called Tabapsy to help people with mental health conditions who smoke. The program includes information meetings, assessments, and workshops on quitting. Researchers will compare it to usual care in 6,500 adults from psychiatric clinics, measuring if th…
Phase: NA • Sponsor: GCS-CCOMS • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Can a computer avatar help you quit smoking? baltimore study aims to find out
Disease control Recruiting nowThis pilot study tests a new way to help adults aged 50 and older quit smoking. Participants interact with a virtual counselor on a computer, receive nicotine patches and gum or lozenges, and get support from a community health worker who also helps them schedule lung cancer scre…
Phase: PHASE4 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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E-Cigs plus coaching may help mentally ill smokers cut harm
Disease control Recruiting nowThis study tests whether giving e-cigarettes to smokers with mental illness—along with optional behavioral coaching—helps them switch from regular cigarettes and lower their exposure to harmful chemicals. The trial enrolls 250 daily smokers who have tried to quit before but aren'…
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Can Ultra-Low nicotine smokes help break the habit for those in pain?
Disease control Recruiting nowThis study is testing whether switching to very low nicotine cigarettes can reduce cravings, withdrawal, and pain in people who smoke daily, have chronic pain, and are on buprenorphine for opioid use disorder. Sixty participants will be randomly assigned to either very low nicoti…
Phase: NA • Sponsor: Duke University • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Proactive pharmacist calls could help HIV patients kick the habit
Disease control Recruiting nowThis study tests a proactive approach to help people living with HIV quit smoking. A pharmacist calls participants, offers counseling, and sends cessation medication unless they opt out. The goal is to see if this method works better than standard care. The trial involves 231 adu…
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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New device aims to break vaping addiction without drugs
Disease control Recruiting nowThis study tests the VapeAway system, a drug-free program that uses special filters to slowly lower nicotine intake, a sensory tool called the Fix Bar, and digital support to help people stop vaping. About 70 motivated adults who vape daily will use the system for 42 days. Resear…
Phase: PHASE2 • Sponsor: VapeAway • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Can a pouch replace a cigarette? new study tests zyn as a smoking swap
Disease control Recruiting nowThis study looks at whether tobacco-free nicotine pouches (like Zyn) can help people switch from smoking cigarettes. Fifty smokers will get either low (3 mg) or high (6 mg) nicotine pouches to use for 4 weeks. Researchers will check if they stop smoking and how much they use the …
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Can a phone app help people with HIV kick the smoking habit?
Disease control Recruiting nowThis study compares two smartphone apps designed to help people living with HIV quit smoking. Participants will use one of the apps for about six months and also receive nicotine patches and gum. The goal is to see which app works better at helping people stay smoke-free, using b…
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Vaping cessation pill under trial: varenicline tested on 326 adults
Disease control Recruiting nowThis study tests whether the medication varenicline can help adults quit using e-cigarettes. Researchers will compare varenicline to a placebo in 326 people who vape daily. The main goal is to see if more participants can stop vaping for at least a week by the 12-week mark, with …
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Brain zaps to kick the habit: TMS trial targets smokers with mental health struggles
Disease control Recruiting nowThis study tests whether a non-invasive brain stimulation technique called TMS can help people with mental illness quit smoking. Forty daily smokers with psychiatric conditions will receive either TMS or standard care. The goal is to see if TMS is practical and effective in real-…
Phase: PHASE4 • Sponsor: Centre for Addiction and Mental Health • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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New trial aims to help homeless smokers kick the habit for good
Disease control Recruiting nowThis study tests whether nicotine replacement therapy (patches, gum, or lozenges) plus wellness coaching over the phone can help people experiencing homelessness quit smoking. Researchers will enroll 150 adults in San Francisco and Los Angeles who smoke at least 5 cigarettes a da…
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Peer power: new study tests if support buddies boost HIV med adherence
Disease control Recruiting nowThis study tests whether trained peer recovery specialists can help Black individuals with substance use stick to their long-acting injectable HIV treatment or prevention. 186 participants will either get this peer support or standard care. The goal is to see if the peer program …
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Veterans offered cash rewards to quit smoking before surgery in new mobile app trial
Disease control Recruiting nowThis study tests a mobile app and financial rewards to help veterans quit smoking before major elective surgery. Smoking increases the risk of complications after surgery, but quitting can be hard. The program uses a carbon monoxide monitor and app to verify abstinence, with ince…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Nicotine pouches tested as a way to help smokers quit
Disease control Recruiting nowThis study tests whether nicotine pouches can help smokers reduce their cigarette use. 375 smokers who smoke at least 5 cigarettes a day will be given different strengths and flavors of nicotine pouches to use for 16 weeks. Researchers will measure changes in cigarette smoking an…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Can safety managers help construction workers kick the habit?
Disease control Recruiting nowThis study tests a smoking cessation program in the construction industry, where safety managers are trained to help workers quit smoking. About 608 construction workers will receive nicotine gum and access to a telephone quit-line. The goal is to find the most effective and cost…
Phase: PHASE4 • Sponsor: University of Miami • Aim: Disease control
Last updated Jun 26, 2026 12:43 UTC
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Phone screening could catch mouth cancer earlier in rural villages
Diagnosis Recruiting nowThis study tests whether using mobile health (mHealth) tools helps find early signs of oral cancer better than the usual visual exam in rural areas of Varanasi, India. Over 5,000 adults with risk factors like smoking, tobacco use, or age over 40 will be screened. The goal is to c…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Diagnosis
Last updated Jun 27, 2026 12:36 UTC
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Can a family advocate help break the cycle of trauma and addiction?
Prevention Recruiting nowThis study tests whether adding a trained family advocate to a proven parenting program can help prevent substance use and reduce childhood trauma. About 360 families from 36 high-risk communities in New Jersey will take part. The goal is to see if extra support makes the program…
Phase: NA • Sponsor: RTI International • Aim: Prevention
Last updated Jun 27, 2026 12:28 UTC
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5,000 smokers to test new digital nudge vs. standard care in cancer prevention trial
Prevention Recruiting nowThis study compares two ways to help people stop smoking and lower their cancer risk. About 5,000 adults who smoke and visit a participating clinic will be assigned to either a program that uses personalized reminders and support (ELEVATE-S) or standard quit-focused care (ELEVATE…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Prevention
Last updated Jun 27, 2026 08:10 UTC
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Texts and cash: a new hope for pregnant smokers?
Symptom relief Recruiting nowThis study tests whether combining text message support with financial incentives helps low-income pregnant women quit smoking more than text messages alone. Thirty pregnant women who smoke will be split into two groups to see which approach is more acceptable and effective. The …
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Symptom relief
Last updated Jul 02, 2026 00:00 UTC
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New study aims to help teens kick the vaping habit
Symptom relief Recruiting nowThis study tests a behavioral program called QuitVaping, which combines counseling sessions with text message support, to help teenagers aged 14-18 quit vaping. About 400 participants who vape nicotine at least weekly will be randomly assigned to either the QuitVaping program or …
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jul 01, 2026 00:00 UTC
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Can a smartphone app help young adults kick the tobacco habit?
Symptom relief Recruiting nowThis study compares two versions of a smartphone app called Living Free from Tobacco (LiFT) to help young adults ages 18-30 quit using nicotine and tobacco products. About 140 participants will use one of two app versions: one focuses on building mental flexibility to support qui…
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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Can a chatbot help you quit smoking? new study aims to find out
Symptom relief Recruiting nowThis study tests a smartphone chatbot designed to help Black adults quit smoking. The chatbot sends alerts during times when a person is most likely to smoke and suggests ways to handle triggers. 120 participants will be randomly assigned to use the chatbot or not, and researcher…
Phase: NA • Sponsor: University of Minnesota • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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New app aims to help young adults kick the vaping habit
Symptom relief Recruiting nowThis study tests a smartphone app called ACT on Vaping to help young adults (ages 18-30) quit using e-cigarettes. The app uses behavioral therapy to help users recognize triggers and build skills to stop vaping. About 1,178 participants will use the app or a control, and research…
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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COPD patients may breathe easier by switching to heated tobacco
Symptom relief Recruiting nowThis study looks at whether people with COPD and chronic bronchitis who switch from regular cigarettes to a tobacco heating system feel better and breathe easier. About 290 adults aged 40 and older who have smoked for at least 10 years will take part. Researchers will measure cou…
Phase: NA • Sponsor: Philip Morris Products S.A. • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New program aims to ease mental health struggles by targeting shared roots
Symptom relief Recruiting nowThis study tests a program called SKILLS that focuses on common factors across different mental health conditions, rather than treating each disorder separately. About 60 adults with stable psychiatric diagnoses will take part. The goal is to see if this approach reduces symptoms…
Phase: NA • Sponsor: University Hospital, Tours • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC
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New program aims to help pregnant smokers kick the habit
Symptom relief Recruiting nowThis study tests a new program where community health workers provide extra support to pregnant women who smoke. The goal is to help them quit smoking during pregnancy. About 105 women in San Bernardino County will take part and receive coaching to stop tobacco use.
Phase: NA • Sponsor: Loma Linda University • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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Teens fight vaping addiction with social media support groups
Symptom relief Recruiting nowThis study tests a social media program called Quit the Hit Toolkit to help teens and young adults stop vaping. Coaches are trained to lead small support groups for 5 weeks. The goal is to see if this approach is practical and helpful for quitting nicotine.
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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Yoga vs. tobacco: can stretching away the urge help you quit?
Symptom relief Recruiting nowThis study tests whether yoga can lower tobacco cravings in men aged 18-65 who want to quit. 96 participants will either do low-impact yoga or receive standard quitting advice. Researchers will measure cravings and relapse over three months to see if yoga is a helpful addition.
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
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Exercise program aims to help anxious smokers kick the habit
Symptom relief Recruiting nowThis study tests whether a personalized exercise program can help smokers who are afraid of bodily sensations (like a racing heart) quit smoking. 360 adults will take part at YMCA locations. The goal is to see if exercise reduces smoking relapse and helps people stay smoke-free f…
Phase: PHASE3 • Sponsor: Jasper A. Smits • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Diabetes drug shows promise to help smokers kick the habit
Symptom relief Recruiting nowThis study tests whether semaglutide, a drug used for diabetes, can help people with type 2 diabetes quit smoking. About 100 adults in Ontario who smoke at least 5 cigarettes daily will receive the drug alongside nicotine replacement therapy. The main goal is to see if a larger s…
Phase: PHASE3 • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Free online mindfulness program aims to help smokers and vapers quit
Symptom relief Recruiting nowThis study tests a free, internet-based program that uses mindfulness and behavioral strategies to help adults reduce or quit smoking and vaping. About 406 participants in Switzerland and Türkiye will be randomly assigned to the program or a control group. The program includes ei…
Phase: NA • Sponsor: University of Zurich • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Sniff your way to quit? early trial tests scent device for cigarette cravings
Symptom relief Recruiting nowThis early-phase study tests whether a device that delivers specific smells can reduce cigarette cravings and help people stop smoking. About 132 smokers will use a smartphone app with or without the scent device for a week, then report cravings and quit attempts. The goal is to …
Phase: EARLY_PHASE1 • Sponsor: University of Houston • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Healing beats: music therapy tested as addiction treatment in major european trial
Symptom relief Recruiting nowThis study is testing whether music therapy can help people with substance use disorder. 600 participants across Europe will be randomly assigned to either active music-making, music listening, or standard treatment. The goal is to see if music therapy improves addiction severity…
Phase: NA • Sponsor: NORCE Norwegian Research Centre AS • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Can a smartphone app help you kick the habit? new study tests digital mindfulness for smoking cessation
Symptom relief Recruiting nowThis pilot study tests a smartphone app called eMind that delivers an 8-week mindfulness programme to help smokers quit. Researchers want to see if smokers find the app acceptable and easy to use. The study involves 40 adult smokers motivated to quit, who will use the app and pro…
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Zapping the brain to kick the habit: new trial tests rTMS for smoking cessation
Symptom relief Recruiting nowThis study tests whether a non-invasive brain stimulation technique called rTMS can help people stop smoking. Researchers will use MRI scans to guide the stimulation to brain areas involved in craving and self-control. The trial involves 64 smokers who will receive either real or…
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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New smoking cessation program aims to help Chicago's behavioral health patients quit
Symptom relief Recruiting nowThis study partners with community organizations to adapt a smoking cessation program for adults who smoke and receive care at behavioral health clinics. Researchers will enroll 24 participants to test whether the program is feasible and acceptable. The goal is to learn how to be…
Phase: NA • Sponsor: University of Chicago • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Ear seeds could help psychiatric patients kick smoking withdrawal symptoms
Symptom relief Recruiting nowThis pilot study tests whether adding ear acupressure (small seeds taped to ear points) to standard nicotine patches or gum can reduce cravings, withdrawal symptoms, and anxiety in psychiatric inpatients who must stop smoking during their hospital stay. Sixty participants will be…
Phase: NA • Sponsor: Chiao-Chiao Liao • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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New study tests social media and chatbot to help teens kick vaping habit
Symptom relief Recruiting nowThis study is testing whether a social media and smartphone app program can help teens and young adults who vape to cut back or quit. Participants will be recruited through social media, screened by a chatbot, and given a mobile app with tailored tips and encouragement. The goal …
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Could VR therapy help heal emotional wounds?
Symptom relief Recruiting nowThis study is testing whether a virtual reality version of a therapy exercise is practical and helpful for adults (ages 18-65) with psychiatric disorders. Participants will try one VR session and answer questions about their experience. The goal is to see if this approach is acce…
Phase: NA • Sponsor: University Medical Center Groningen • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Brain zaps to kick the habit? new trial tests rTMS for smoking cessation
Symptom relief Recruiting nowThis study tests whether a non-invasive treatment called repetitive transcranial magnetic stimulation (rTMS) can help daily smokers quit. rTMS uses magnetic pulses to stimulate brain areas involved in addiction and decision-making. Forty participants will receive daily sessions f…
Phase: PHASE4 • Sponsor: Centre for Addiction and Mental Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Simple chest exercises may boost lung health in young smokers
Symptom relief Recruiting nowThis study tests whether specific chest exercises can improve breathing, chest expansion, and exercise capacity in university students who smoke. Thirty smokers aged 18-24 will be split into two groups: one doing chest PNF techniques and the other doing chest mobility exercises. …
Phase: NA • Sponsor: University of Yalova • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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New online therapy aims to quiet the inner critic
Symptom relief Recruiting nowThis study is testing a type of talk therapy called Emotion Regulation Therapy (ERT) delivered over video for people in New York who struggle with worry, overthinking, or being hard on themselves. The goal is to see if the therapy helps people better manage their emotions and fee…
Phase: NA • Sponsor: Teachers College, Columbia University • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Brain zaps to zap vaping: new study tests tDCS for E-Cig addiction
Symptom relief Recruiting nowThis study tests whether a non-invasive brain stimulation technique called tDCS can help people who vape nicotine daily to cut back. Forty adults aged 18-65 who vape regularly will receive either real or fake tDCS for 10 sessions over two weeks. Researchers will measure changes i…
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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New program aims to help asian american smokers quit and catch lung cancer early
Symptom relief Recruiting nowThis study tests a program designed specifically for Chinese and Korean American smokers who are at high risk for lung cancer. The program includes counseling sessions, family coaching, nicotine replacement therapy (like patches or gum), and information about lung cancer screenin…
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Brain scans reveal how therapy may help schizophrenia patients kick the habit
Symptom relief Recruiting nowThis study tests whether a type of talking therapy called Acceptance and Commitment Therapy (ACT) can help people with schizophrenia quit smoking and reduce their psychotic symptoms. Researchers will use brain scans (fMRI) to see if the therapy changes how the brain responds to c…
Phase: NA • Sponsor: The Hong Kong Polytechnic University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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AI dentist could help smokers kick the habit
Symptom relief Recruiting nowThis study tests whether a dental health evaluation using AI can help people stop smoking. 300 adult smokers who want to quit will get an AI analysis of their mouth and teeth. The main goal is to see if more people have quit smoking after 6 months, confirmed by a breath test.
Phase: NA • Sponsor: Fayoum University • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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New sleep aid studied for those with mental illness
Symptom relief Recruiting nowThis study looks at how well and how safely a new sleep medication, lemborexant, works for people who have both a mental health condition and trouble sleeping. About 121 adults will take the drug for 8 weeks, and researchers will track changes in their sleep quality and any side …
Sponsor: Shanghai Mental Health Center • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Brain zaps to kick the habit: new study for veterans with PTSD
Symptom relief Recruiting nowThis study tests a new way to help veterans with PTSD stop smoking. It combines counseling, nicotine gum, and a noninvasive brain stimulation called TMS. Researchers want to see if this approach is practical and helps veterans stay smoke-free for at least 3 months. About 50 veter…
Phase: PHASE2 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Can your phone help you quit smoking? new study tests AR app
Symptom relief Recruiting nowThis study tests whether a smartphone app that uses augmented reality (AR) can help people quit smoking when used alongside standard quitline counseling. The app shows smoking-related cues to help users manage cravings. The trial will enroll 3,600 adult daily smokers and measure …
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Brain zapping without surgery shows promise for nicotine cravings
Symptom relief Recruiting nowThis study tests a new, non-invasive brain stimulation method called temporal interference (TI) to reduce nicotine cravings and vaping. 120 adults who vape heavily will receive either real TI stimulation to deep brain areas linked to addiction or a sham (fake) treatment during a …
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Kava: a natural aid to kick the smoking habit?
Symptom relief Recruiting nowThis study looks at whether a daily dose of kava can help smokers who want to quit. Researchers will check if kava makes it easier to stop smoking, reduces stress, and improves sleep. About 76 adults who smoke at least 5 cigarettes a day and want to quit will take part for 4 mont…
Phase: PHASE2 • Sponsor: University of Florida • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Can an app kick the vaping habit? new trial tests digital therapy for teens
Symptom relief Recruiting nowThis study tests whether a smartphone app called Kick-Nic! can help high school students (ages 13-19) quit vaping. About 306 participants who want to quit will either use the app or visit a standard quit-vaping website for 8 weeks. Researchers will check if they've stopped vaping…
Phase: PHASE2 • Sponsor: Yale University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Can sound and vibration calm troubled teens? new trial aims to find out
Symptom relief Recruiting nowThis study tests a multi-sensory therapy called Heal, which uses calming sounds, gentle vibrations, and soft lighting to help detained youth (ages 12-18) manage their emotions before counseling sessions. The goal is to see if this brief, non-verbal intervention improves emotional…
Phase: NA • Sponsor: SoundHeal • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Could a nicotine patch replace opioids for Post-Surgery pain in smokers?
Symptom relief Recruiting nowThis pilot study is testing whether a high-dose nicotine patch can reduce pain and the need for opioid painkillers in male smokers who are having chest surgery. The patch is given before and after surgery. The study will track how much pain medication participants use. It include…
Phase: NA • Sponsor: Henan Provincial People's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Sailing therapy: a new wind for psychiatric care?
Symptom relief Recruiting nowThis study tests whether sailing can help people with psychiatric disorders feel better. Forty adults in France will either take sailing lessons or continue their usual care. Researchers will measure changes in quality of life, mental well-being, and self-esteem to see if sailing…
Phase: NA • Sponsor: Centre hospitalier de Ville-Evrard, France • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Zapping the brain to kick the habit: new hope for smokers with schizophrenia
Symptom relief Recruiting nowThis study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can help people with schizophrenia spectrum disorder quit or reduce smoking. Fifty participants will receive active rTMS using either an F8 coil or an H …
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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VR meditation may help smokers kick the habit
Symptom relief Recruiting nowThis study tests whether mindfulness meditation in virtual reality can reduce cigarette cravings and help people quit smoking. Two hundred smokers will be split into two groups: one gets six VR meditation sessions over six weeks, and the other uses nicotine patches and gum. Resea…
Phase: NA • Sponsor: Centre Hospitalier Henri Laborit • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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CBD: the new tool to kick the smoking habit?
Symptom relief Recruiting nowThis study tests whether a daily oral dose of cannabidiol (CBD) can help people stop smoking tobacco. Fifty adults who smoke more than 10 cigarettes a day and want to quit will take CBD during several practice quit attempts. The goal is to see if CBD increases short-term abstinen…
Phase: PHASE1 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Can peer support keep drug users in the ER and save lives?
Symptom relief Recruiting nowThis study tests whether peer support workers—people with lived experience of substance use—can help people who use drugs feel safer and stay in the emergency department until their care is complete. The study will compare what happens when peer workers are on shift versus when t…
Phase: NA • Sponsor: University of British Columbia • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Can a double-dose of quit-smoking meds help pancreatitis patients kick the habit?
Symptom relief Recruiting nowThis study tests whether increasing the dose of varenicline or adding bupropion helps people with recurrent acute or chronic pancreatitis quit smoking. All 45 participants start with standard varenicline; those still smoking after 6 weeks are randomly assigned to a higher dose, a…
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Tailored smoking cessation for cancer patients shows promise
Symptom relief Recruiting nowThis study tests whether a personalized approach to smoking cessation helps cancer patients quit. Researchers will use patients' clinical, genetic, and biomarker information to create tailored treatment plans. The study involves 112 participants and compares this precision treatm…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Could an antibiotic ingredient help smokers quit?
Symptom relief Recruiting nowThis study tests whether clavulanic acid, a drug used to boost antibiotics, can help people smoke less. Thirty adult smokers will take either the drug or a placebo for several weeks. Researchers will measure smoking levels and use brain scans to see if the drug changes how the br…
Phase: PHASE2 • Sponsor: University of Missouri-Columbia • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Chatbot coach aims to help smokers kick the habit
Symptom relief Recruiting nowThis study tests a digital coaching program that uses a chatbot to help people quit smoking. The program aims to boost motivation, educate about quitting tools, and create a personalized quit plan. Researchers will enroll 440 adult smokers and check if they have quit after 6 mont…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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New antibody shot could trap nicotine in smokers
Symptom relief Recruiting nowThis early-stage study tests a new drug called ATI-1013 in 15 healthy smokers. The drug is an antibody designed to bind to nicotine in the body. The main goal is to check safety and see how long the drug stays in the system. Participants get one IV dose of the drug or a placebo a…
Phase: PHASE1 • Sponsor: Antidote Therapeutics, Inc • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Sleep therapy may boost quit rates for tobacco and cannabis users
Symptom relief Recruiting nowThis pilot study tests whether screening and treating sleep disorders during tobacco or cannabis cessation therapy helps people stay abstinent longer. 80 participants will either get usual care or extra sleep-focused care. The study follows them for 6 months to see if addressing …
Phase: NA • Sponsor: Centre Hospitalier St Anne • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Veterans get paid to quit smoking in new VA study
Symptom relief Recruiting nowThis study tests a program called Contingency Management that gives Veterans rewards for quitting smoking, verified by breath tests. Researchers will first gather feedback from Veterans and staff, then run a small pilot with 20 Veterans over 5 weeks. If successful, a larger trial…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Brain zaps to beat cravings: paris trial tests tDCS for smokers
Symptom relief Recruiting nowThis study tests whether a non-invasive brain stimulation technique called tDCS can reduce cravings in people addicted to nicotine. One hundred daily smokers who are highly dependent will receive tDCS sessions. The goal is to see if this painless, mild electrical stimulation can …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 26, 2026 16:02 UTC
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CBD put to the test: could it curb cravings and calm nerves in smokers?
Symptom relief Recruiting nowThis early-stage study at Johns Hopkins is testing whether cannabidiol (CBD) can reduce stress and nicotine withdrawal symptoms in people who smoke. Ninety healthy smokers will receive CBD and then be exposed to stress while researchers measure their mood, heart rate, and stress …
Phase: PHASE1 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 26, 2026 13:08 UTC
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Massive smartphone study aims to unlock secrets of addiction relapse
Knowledge-focused Recruiting nowThis study aims to create a large data repository by collecting smartphone data and daily surveys from 10,000 adults who use alcohol or drugs. Participants will use an app that tracks phone activity and location, and answer short surveys about mood and substance use. The goal is …
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated Jul 03, 2026 23:00 UTC
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Nicotine's brain impact on depression under the microscope
Knowledge-focused Recruiting nowThis study looks at how nicotine changes brain function in people with and without major depressive disorder (MDD). Researchers will give 620 non-smokers either a nicotine patch or a placebo and then scan their brains using MRI. Participants will also answer questions about their…
Phase: NA • Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Scientists use advanced MRI to map addiction in the brain
Knowledge-focused Recruiting nowThis study is developing new MRI techniques to better understand how drug addiction changes the brain. Researchers will scan 1,000 healthy adults, smokers, and drug users to improve imaging methods. The goal is to create tools that can reveal the brain's structure and function in…
Phase: NA • Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Brain zaps for smokers: personalized therapy on the horizon?
Knowledge-focused Recruiting nowThis study aims to understand why some people respond better to a brain stimulation treatment (rTMS) for smoking. Researchers will measure brain activity in 100 smokers aged 21-60 to see if emotional triggers affect treatment success. The goal is to personalize future therapies f…
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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E-Cig coolants may boost appeal – study investigates
Knowledge-focused Recruiting nowThis study looks at how cooling ingredients like WS-3 and menthol in e-cigarettes affect how much people like them and find them addictive. Researchers will have 66 adult e-cigarette users try different e-liquid mixtures and report their feelings of liking, craving, and harshness…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Can a 48-Hour psychiatrist booking system keep patients out of the ER?
Knowledge-focused Recruiting nowThis study compares two ways to help adults with mental health issues get follow-up care. One group gets usual care after an emergency room visit, while the other uses a new system that books a psychiatrist appointment within 48 hours through their general doctor. Researchers wil…
Phase: NA • Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Little cigars under the microscope: new study reveals hidden health risks
Knowledge-focused Recruiting nowThis study looks at how smoking little cigars affects levels of harmful chemicals called oxidants in the body. Researchers will compare three types of smoking: high-oxidant little cigars, low-oxidant little cigars, and regular cigarettes. Fifty daily smokers will provide breath, …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Yale scientists seek Nicotine's 'Addiction Threshold' in smokers
Knowledge-focused Recruiting nowThis study aims to find the smallest amount of nicotine that smokers find rewarding or addictive. Researchers will test different nicotine doses in 45 adult smokers to see which dose they can identify and prefer. The goal is to better understand how addiction develops, which coul…
Phase: EARLY_PHASE1 • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:08 UTC
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Can kicking nicotine change cannabis habits? study investigates
Knowledge-focused Recruiting nowThis study looks at young adults aged 18 to 25 who use both tobacco/nicotine products and cannabis. Researchers want to understand what happens to cannabis use when participants try to quit nicotine. All participants receive remote counseling and incentives to stop using nicotine…
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Study to uncover hidden mental health struggles in teens at special schools
Knowledge-focused Recruiting nowThis study looks at the mental health of 200 teenagers aged 12 to 16 who attend special educational institutes (ITEPs) in France. Researchers will use psychiatric interviews to find out how many have conditions like depression or anxiety. The goal is to better understand their ne…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Can data sharing prevent suicide among Jail-Cycling individuals?
Knowledge-focused Recruiting nowThis study aims to improve suicide prevention for people who move between healthcare and the criminal-legal system. Researchers will link health records, Medicaid data, and jail booking information to identify individuals at risk and coordinate care. Over 1,000 adults with past p…
Phase: NA • Sponsor: Cambridge Health Alliance • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Scientists probe why only some smokers develop lung disease
Knowledge-focused Recruiting nowThis study looks at why some smokers develop COPD while others don't. Researchers will collect lung cells from 40 former smokers using a bronchoscopy and analyze them to find differences in immune cells called macrophages. The goal is to understand the biological reasons behind C…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Sleep drug could rewire brain to fight nicotine addiction
Knowledge-focused Recruiting nowThis study tests whether suvorexant, a drug approved for insomnia, can reduce cravings and brain responses linked to smoking in daily smokers. Researchers will also study how it affects thinking and reward processing in non-smokers. The goal is to understand if blocking a brain c…
Phase: NA • Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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E-Cig flavor study targets smokers with opioid addiction
Knowledge-focused Recruiting nowThis study looks at how different e-cigarette flavors appeal to adults who have opioid use disorder and are on buprenorphine treatment. Participants will smell and rate 11 flavors for sweetness, coolness, strength, and how likely they'd use them again. The goal is to find flavors…
Sponsor: Prisma Health-Upstate • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Gut bacteria may hold key to smoking cessation in addiction recovery
Knowledge-focused Recruiting nowThis study looks at how stopping smoking for six weeks affects the body's chemistry and gut bacteria in people being treated for substance use disorders. Researchers will compare 100 participants who quit smoking with 50 healthy controls, using blood and stool samples along with …
Phase: NA • Sponsor: Sigmund Freud PrivatUniversitat • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Teamwork triumph: study explores how couples can quit smoking together
Knowledge-focused Recruiting nowThis study looks at how romantic partners who both smoke can support each other when trying to quit. Researchers will ask 250 couples to fill out daily surveys for two weeks while attempting to quit, tracking their smoking, cravings, and stress. The goal is to understand which ty…
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Synthetic vs. natural nicotine: which hits harder?
Knowledge-focused Recruiting nowThis study looks at how the body handles synthetic nicotine compared to natural nicotine from tobacco. Eighteen experienced e-cigarette users will vape three different nicotine blends in a controlled setting. Researchers will measure nicotine levels in the blood, heart effects, c…
Phase: PHASE1 • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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New program aims to slash lung cancer deaths in african american smokers
Knowledge-focused Recruiting nowThis study tests a program that combines help with quitting smoking and getting a lung cancer screening (a special CT scan) for African American smokers. The goal is to reduce the high rate of lung cancer in this group. About 250 people will take part, and researchers will track …
Phase: NA • Sponsor: Louisiana State University Health Sciences Center in New Orleans • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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AI analyzes your surroundings to predict smoking relapse
Knowledge-focused Recruiting nowThis study recruits 600 adults who want to quit smoking. Participants use a smartphone app to take photos of their environment when they smoke and at random times. Researchers use artificial intelligence to analyze these images and identify environmental triggers that lead to rel…
Phase: PHASE4 • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Flavored cigarillo study seeks young smokers to test policy scenarios
Knowledge-focused Recruiting nowThis study recruits 300 young adults aged 18-24 who smoke cigarillos to understand how different flavors influence their smoking behavior and perceptions. Researchers will measure puff counts and self-reported rewards from smoking, and simulate how changing flavor availability mi…
Phase: NA • Sponsor: University of Oklahoma • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Brain training may curb multiple drug use, new study suggests
Knowledge-focused Recruiting nowThis study tests whether combining neurofeedback with integrative body-mind training can change brain function and reduce cravings and substance use in adults who regularly use alcohol, cannabis, and cigarettes. Researchers will use brain scans to measure changes in connectivity …
Phase: NA • Sponsor: Arizona State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Scientists scan brains to catch smoking lapses before they happen
Knowledge-focused Recruiting nowThis study uses brain scans (fMRI) to see what happens in the brain just before a smoker lapses (takes a cigarette during a quit attempt). Researchers will have 150 smokers complete a task where they can delay smoking for money, while their brain activity and feelings are measure…
Phase: NA • Sponsor: Penn State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Pakistan tests digital mental health guide for substance use in primary care
Knowledge-focused Recruiting nowThis study aims to see if a digital version of the WHO's mental health guide for substance use disorders can be used effectively in primary care settings in Pakistan. Researchers will train 300 primary care doctors in three major cities using this digital tool. The goal is to und…
Phase: NA • Sponsor: Pakistan Institute of Living and Learning • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Can a smartphone app help african americans quit smoking? new study investigates.
Knowledge-focused Recruiting nowThis study aims to understand what makes it easier or harder for African American smokers to use a smartphone app designed to help them quit. Researchers will first get feedback from a small group to improve the app, then test it with 30 people who want to quit. The app sends rem…
Phase: NA • Sponsor: University of Oklahoma • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Psychedelics rewire Brain's learning? yale study investigates
Knowledge-focused Recruiting nowThis observational study at Yale University is recruiting 200 people who are already taking part in another trial where they may receive a serotonergic psychedelic (like psilocybin or LSD) or a placebo. Researchers want to understand how these substances change the brain's inform…
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Brain scans reveal how common drugs may dull smoking urges
Knowledge-focused Recruiting nowThis study looks at how the drug propranolol and nicotine patches, alone or together, change brain activity and cravings when smokers see smoking-related cues. Eighty daily smokers will undergo brain scans while viewing these cues. The goal is to understand the brain mechanisms b…
Phase: PHASE4 • Sponsor: University of Oklahoma • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Can nicotine pouches replace cigarettes? new study aims to find out
Knowledge-focused Recruiting nowThis study looks at whether oral nicotine pouches (like ZYN) can be a good substitute for cigarettes or smokeless tobacco. Researchers will test different nicotine levels and forms to see which ones reduce cravings and appeal to users. 160 adult tobacco users will try the pouches…
Phase: PHASE2 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Cannabis compound may change how you vape
Knowledge-focused Recruiting nowThis study looks at how THC, the active part of cannabis, changes people's desire for e-cigarettes and their body's response. Researchers will give different doses of THC to 100 adults who use both e-cigarettes and cannabis, then measure how much they vape, their cravings, heart …
Phase: PHASE1 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Childhood trauma may rewire brain to crave nicotine
Knowledge-focused Recruiting nowThis study looks at how difficult childhood experiences might change brain function and make people more likely to start smoking. Researchers will give a small dose of nicotine or a placebo to 150 nonsmoking young adults aged 18-21, then use brain scans and questionnaires to meas…
Phase: EARLY_PHASE1 • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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VR goggles could reveal secrets of smoking cravings
Knowledge-focused Recruiting nowThis study looks at whether virtual reality (VR) can measure how smokers pay attention to smoking-related cues, which may help understand nicotine addiction. Two hundred daily smokers will take either a medication (varenicline) or a placebo, and their eye movements and cravings w…
Phase: EARLY_PHASE1 • Sponsor: University of California, San Diego • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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New study tests nurse support for Ex-Prisoners' health
Knowledge-focused Recruiting nowThis study looks at whether a program with a nurse case manager can help people leaving prison visit a doctor or clinic instead of the emergency room. About 488 adults with a history of substance use and a chronic health condition will take part. Some will get extra support from …
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Study pits e-cigarettes against nicotine pouches to help smokers quit
Knowledge-focused Recruiting nowThis study looks at whether e-cigarettes or oral nicotine pouches can help people who smoke cigarettes cut down or switch completely. Two hundred adult smokers who have tried to quit before will be randomly assigned to use one of these products instead of cigarettes for six weeks…
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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New study tests simple chat to boost addiction treatment success
Knowledge-focused Recruiting nowThis study looks at whether using a special counseling style called Motivational Interviewing during the first visit can help people stay in addiction treatment. Researchers will compare this approach to the usual intake process. About 150 adults seeking outpatient addiction trea…
Phase: NA • Sponsor: University of New Mexico • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Vapers vs. smokers: who has worse withdrawal?
Knowledge-focused Recruiting nowThis study looks at how daily vapers and cigarette smokers experience withdrawal when they stop using nicotine for 24 hours. Researchers will measure mood, cravings, attention, and other symptoms in 370 participants. The goal is to better understand nicotine dependence and help d…
Phase: NA • Sponsor: State University of New York at Buffalo • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Quitting smoking may ease pain risk for native americans
Knowledge-focused Recruiting nowThis study looks at whether Native American adults who smoke can lower their risk of chronic pain by quitting smoking for 4 weeks. Researchers will measure pain sensitivity and other health markers before and after a stop-smoking program. The goal is to see if this approach is fe…
Phase: NA • Sponsor: University of Oklahoma • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Study probes which nicotine pouches hook users most
Knowledge-focused Recruiting nowThis study looks at how the amount of nicotine and the pH level in nicotine pouches influence how appealing and addictive they feel to young adult users. Researchers will have 84 participants try different pouches and rate their experience. The goal is to help regulators understa…
Phase: NA • Sponsor: Emory University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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New tool helps new moms with addiction choose the right birth control
Knowledge-focused Recruiting nowThis study looks at whether a tool called MyPath helps women with substance use disorder make better decisions about birth control after having a baby. About 400 women will use the tool during pregnancy or right after delivery. The goal is to see if it helps them pick a method th…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Nicotine pouches under the microscope: do they hook new users?
Knowledge-focused Recruiting nowThis study at Johns Hopkins University is testing nicotine pouches (like Zyn) in 120 adults—60 regular smokers and 60 people who rarely use nicotine. Participants will use the pouches in two lab sessions while researchers measure how much nicotine gets into the blood, how appeali…
Phase: PHASE1 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Fruity vs. tobacco: which E-Cig flavor gets smokers to quit?
Knowledge-focused Recruiting nowThis study looks at whether the flavor of e-cigarettes helps smokers switch from regular cigarettes. 210 smokers who have tried to quit before will use fruit, tobacco, or menthol flavored e-cigarettes for 6 weeks. Researchers will track how many cigarettes they smoke and how sati…
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Relighting your cigarette? study says it may boost toxins
Knowledge-focused Recruiting nowThis study aims to understand if relighting a cigarette (smoking it in parts) produces more harmful chemicals than smoking it all at once. Researchers will observe 30 smokers who already relight their cigarettes, measuring their smoking habits and collecting cigarette butts. No t…
Phase: NA • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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THC may change how much you crave a cigarette, study finds
Knowledge-focused Recruiting nowThis study looks at how THC, the active part of cannabis, affects cigarette cravings and smoking habits. Researchers will give 100 adults who smoke both tobacco and cannabis different doses of THC or a placebo, then measure how many cigarette puffs they take and how they feel. Th…
Phase: PHASE1 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New study investigates the combined effects of marijuana and tobacco
Knowledge-focused Recruiting nowThis study looks at what happens when people who regularly use both marijuana and tobacco use them together. Researchers will measure how much THC and nicotine get into the blood and how the body responds. The goal is to better understand the health effects of using both substanc…
Phase: PHASE2 • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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New nicotine products put to the test: are they less addictive than cigarettes?
Knowledge-focused Recruiting nowThis study enrolls 40 healthy smokers to compare how addictive five new oral nicotine products are compared to their usual cigarettes and Nicorette gum. Participants will use each product in a clinic setting, and researchers will measure their feelings of liking and nicotine leve…
Phase: NA • Sponsor: RAI Services Company • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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New study aims to uncover why opioid and Anti-Anxiety drug mix is so deadly
Knowledge-focused Recruiting nowThis study is looking at 120 people who are already in treatment for abusing opioids and/or benzodiazepines (anti-anxiety drugs). Researchers want to understand why people use these drugs together, which greatly raises the risk of overdose and death. Participants will complete in…
Sponsor: Wayne State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Can better supervision help counselors beat burnout and improve addiction care?
Knowledge-focused Recruiting nowThis study aims to develop and test a supervision strategy for clinical supervisors in substance use disorder treatment programs. The goal is to reduce counselor burnout and turnover, and improve their well-being and performance. About 43 supervisors and counselors from residenti…
Phase: NA • Sponsor: University of Arkansas • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Brain scans reveal how cytisinicline may quiet smoking urges
Knowledge-focused Recruiting nowThis study tests whether the drug cytisinicline changes how the brain reacts to seeing smoking-related images in daily smokers who are not trying to quit. Sixty-four participants will receive either the drug or a placebo and undergo brain scans while watching videos of smoking an…
Phase: PHASE2 • Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Cooking classes aim to boost nutrition for texans in opioid recovery
Knowledge-focused Recruiting nowThis study is testing a cooking and nutrition program for 50 people in Texas who are recovering from opioid use and living in recovery homes while on medication therapy. The program aims to improve their eating habits and confidence in cooking skills. Participants will fill out q…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Massive study tracks 10,000 people with addiction to uncover what really helps
Knowledge-focused Recruiting nowThis study is following 10,000 people who are seeking help for substance or behavioral addictions. Researchers will track their medical, brain, social, and psychological health over several years using interviews, questionnaires, and cognitive tests. The goal is to better underst…
Sponsor: Centre Hospitalier Charles Perrens, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Brain scans reveal why quitting smoking hurts more for chronic pain sufferers
Knowledge-focused Recruiting nowThis study looks at how quitting smoking temporarily increases pain in people with chronic pain, and how the brain processes this. Researchers will use brain scans and daily reports from 132 smokers—some with chronic back pain, some without—to understand these changes. The goal i…
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Brain zaps may rewire Smokers' reward centers
Knowledge-focused Recruiting nowThis study tests whether a non-invasive brain stimulation technique called TMS can change how the brain processes rewards in smokers. Researchers will compare different targeting methods to see which best boosts brain signals related to reward and decision-making. The goal is to …
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Brain zapping study seeks optimal pulse to curb smoking cravings
Knowledge-focused Recruiting nowThis study tests different patterns of transcranial magnetic stimulation (TMS) on the brain's reward center in 42 nicotine-dependent smokers. Researchers measure changes in brain waves and decision-making to find which pulse protocol works best. The goal is to identify the most e…
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Can a simple air monitor help cancer patients breathe cleaner air at home?
Knowledge-focused Recruiting nowThis pilot study at Memorial Sloan Kettering tests whether giving cancer patients an indoor air quality monitor helps them maintain a smoke-free home. Ten participants who smoke and are in a tobacco treatment program will use the monitor for about 60 days. Researchers will see if…
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Can cutting nicotine in little cigars reduce harm?
Knowledge-focused Recruiting nowThis study tests whether very low nicotine little cigars change how people smoke and affect their lungs compared to regular cigars. About 50 adult little cigar smokers will attend three 4-hour visits at Ohio State University. They will fill surveys, give blood, do breathing tests…
Phase: PHASE4 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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ER peer navigators may boost recovery from addiction
Knowledge-focused Recruiting nowThis study looks at whether having a specially trained peer recovery specialist in the emergency department helps people with substance use disorders connect to treatment and support services. Researchers will follow 400 adults who visit the ER for substance-related issues, compa…
Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Low-Nicotine smokes put to the heart test
Knowledge-focused Recruiting nowThis early-phase study is testing whether cigarettes with very low nicotine content cause less strain on the heart compared to regular cigarettes. Researchers will measure heart rate and heart rate variability in 49 daily and non-daily smokers after smoking different types of res…
Phase: EARLY_PHASE1 • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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New program aims to ease Veterans' return from prison
Knowledge-focused Recruiting nowThis study is creating a program called START-VET to help veterans with mental illness or substance use disorders who have recently left prison. Researchers will work with 20 veterans to develop transition materials and tools. The goal is to improve quality of life and reduce cri…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Spit test could take guesswork out of mental health prescriptions
Knowledge-focused Recruiting nowThis pilot study is testing whether a simple saliva test can help doctors prescribe mental health medications more safely and effectively. 200 adults in Manitoba who are starting or changing psychiatric drugs will provide a DNA sample. The results will be shared with their doctor…
Phase: NA • Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:55 UTC
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Can training psychiatric staff improve sexual health talks with teens?
Knowledge-focused Recruiting nowThis study looks at whether training psychiatric care teams to talk about sexual health with young patients (ages 15 and up) increases those conversations. Researchers will survey 770 teens hospitalized for psychiatric disorders about their sexual health and any side effects from…
Sponsor: Fondation Santé des Étudiants de France • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:35 UTC