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Mint vs. fruit: which makes oral nicotine pouches more addictive?

NCT ID NCT06506162

Recruiting now Knowledge-focused Sponsor: University of Southern California Source: ClinicalTrials.gov ↗

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study investigates how flavor (mint vs. fruit) and nicotine strength (2mg vs. 4mg) influence the appeal and abuse liability of oral nicotine gums and pouches. Researchers will recruit 320 young adults aged 21–25 who currently use e-cigarettes exclusively, including a subset of sexual and gender minority participants. Participants will rate sensory appeal and complete tasks measuring motivation to use the products, helping to identify factors that could make these products more addictive.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
oral nicotine products (gums and pouches) with varying flavor (mint vs. fruit) and nicotine strength (2mg vs. 4mg)
What this could lead to
If successful, this research could inform regulations on flavors and nicotine levels in oral nicotine products to reduce their appeal and abuse potential among young adults.
What could go wrong
This is an observational study measuring preferences and behavior, not testing a treatment. Results may not predict real-world use or long-term addiction patterns.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

nicotine dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NICOTINE DEPENDENCE

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Southern California

    RECRUITING

    Los Angeles, California, 90089, United States

  • University of Southern California

    RECRUITING

    Los Angeles, California, 90089, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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