Could a diabetes drug help smokers kick the habit and avoid weight gain?

NCT ID NCT07602699

Recruiting now Symptom relief Sponsor: University of Southern California Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests whether tirzepatide, a drug used for diabetes and weight loss, can help people with overweight or obesity quit smoking. 300 smokers will receive either the drug or a placebo, plus nicotine patches, for 16 weeks. The goal is to see if the drug improves quit rates and reduces weight gain often seen after quitting.

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Conditions

The condition(s) this trial relates to.

Behavior, Addictive nicotine dependence Smoking Smoking Cessation substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SMOKING BEHAVIORS SMOKING CESSATION

Contacts and locations

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Locations

Keck School of Medicine, University of Southern California
RECRUITING

Los Angeles, California, 90033, United States

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University of Chicago Pritzker School of Medicine
RECRUITING

Chicago, Illinois, 60637, United States

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University of Colorado Anschutz Medical Campus
RECRUITING

Aurora, Colorado, 80045, United States

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Yale University School of Medicine
RECRUITING

New Haven, Connecticut, 06510, United States

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