SMOKING CESSATION

This study tests a mindfulness-based program to help cancer survivors stop smoking and reduce heavy drinking. Researchers will compare the program to standard care in 600 survivors across Florida. The goal is to see if mindfulness can improve both habits and be cost-effective.

This study tests a simple online questionnaire (e-visit) to help people stop smoking. About 672 adults who smoke daily will be randomly assigned to receive the e-visit or not. The e-visit asks about smoking habits and preferences for quitting medications, and may offer a prescrip…

This study compares two smoking cessation programs for people undergoing lung cancer screening. About 1,188 participants will receive either a health system-based program or a quitline referral. The goal is to see which approach helps more people quit smoking and stay smoke-free …

This study tests a program to help smoking parents quit by combining brief advice, nicotine replacement therapy, and text message support. Researchers will enroll 1,200 daily smokers in Hong Kong who live with children aged 12 or under and a non-smoking family member. The goal is…

This study tests a personalized smoking cessation program for 424 hospitalized smokers with heart or lung disease. A nurse-led team provides tailored medication, counseling, and text-message support to help patients quit and stay smoke-free. The goal is to improve quit rates and …

This study tests a smoking cessation program designed specifically for people living with HIV. The goal is to help 500 participants quit smoking using a cost-effective approach that is easy for clinics to adopt. The program includes support and nicotine replacement therapy, with …

This study is testing whether a simple indoor air quality monitor can help cancer patients who smoke keep their homes smoke-free. Ten patients from Memorial Sloan Kettering's Tobacco Treatment Program will use the device for two weeks and attend workshops. The goal is to see if t…

This study tests a telehealth program for cancer survivors who smoke, are inactive, or have overweight. Participants either get 12 coaching sessions or just health information. The goal is to see which approach helps more people adopt healthier behaviors. About 1500 adults from N…

This study tests whether offering financial rewards to both a smoker and a family member helps Alaska Native adults quit smoking. About 1,312 participants will be randomly assigned to receive the family-based incentive or standard support. Success is measured by a saliva test at …

This study looks at whether tobacco-free nicotine pouches (like Zyn) can help people who smoke cigarettes switch to a less harmful option. Fifty adult smokers will receive a 28-day supply of pouches and be asked to stop smoking. Researchers will track how many people successfully…

This study tests whether combining text message support with financial rewards helps low-income pregnant women stop smoking more than text messages alone. Researchers will enroll 30 women who smoke daily and are on WIC or Medicaid. The goal is to see if this approach is practical…

This study tests whether an online questionnaire (e-visit) can help rural smokers quit. About 288 adult smokers will be randomly assigned to get the e-visit or not. The e-visit asks about smoking habits and medication preferences, and may lead to a prescription. Participants comp…

This study tests a pharmacist-delivered smoking cessation program called QuitAid for rural smokers in Appalachia. About 768 participants will receive nicotine patches and may also get text support, phone counseling, extra nicotine gum, or pharmacist coaching. The goal is to see w…

This study tests if automated text messages can help people living with HIV quit smoking. Researchers will enroll 800 smokers in Cambodia and provide tailored text support. The goal is to see if this approach helps them stop smoking for good.

This study tests a mobile program called Quitxt that sends tailored texts and videos to help young Latino smokers (ages 18-29) quit. About 1,200 participants will be randomly assigned to get Quitxt or standard quit-smoking information. The goal is to see if the personalized appro…

This study tests whether e-cigarettes or nicotine replacement therapy can help people quit smoking and manage weight gain. Researchers will track daily cigarette use, carbon monoxide levels, and weight changes in 60 adults with obesity who smoke at least 5 cigarettes per day. Par…

This study compares two smartphone apps designed to help people living with HIV quit smoking. About 314 participants will use one of the apps for 24 weeks, along with nicotine patches and gum. The goal is to see which app works better at helping people stay smoke-free, with regul…

This study compares 6 months of bupropion (a quit-smoking medication) against the standard 7-week course in 500 African American daily smokers. The goal is to see if the longer treatment leads to more people staying smoke-free at 6 months. Participants must be interested in quitt…

This study tests a program called Smokefree Family Living (SFL) to help Chinese American smokers quit and reduce harmful smoke residue that lingers on surfaces like carpets and furniture. About 760 Chinese American smokers and their non-smoking family members will take part. The …

This study tests a smoking cessation program designed for LGBTQ+ adults who have high stress and little social support. Participants live in Oklahoma, Texas, or Arkansas and will receive nicotine replacement therapy plus empowerment-based coaching. The goal is to see if this appr…

This study tests whether giving cancer patients personalized recommendations to quit smoking—based on their genes, health history, and lab results—helps them stop more than standard care. About 112 patients and their doctors will take part. The goal is to see if this tailored app…

This study tests a smoking cessation program in the construction industry, where safety managers are trained to help workers quit smoking. About 608 construction workers, safety managers, and company leaders will take part. The goal is to find the most effective and cost-effectiv…

This study tests a new program called QUIT-AD that combines existing methods to help people with HIV or TB quit smoking. The program will be offered to 86 adults in Cape Town, South Africa who smoke daily. Researchers will check if the program is practical, well-liked, and helps …

This study tests a smartphone app designed to help pregnant women stop smoking and stay smoke-free after giving birth. The app uses artificial intelligence to personalize tips and includes a support person chosen by the participant. About 790 pregnant smokers in Romania will be r…

This study is testing a program that combines medication (Naltrexone + Bupropion) with behavior therapy to help adults who smoke and are preparing for weight-loss surgery lose weight and quit smoking. About 20 participants will try the program to see if it is feasible and accepta…

This study tests whether giving smokers a personalized treatment plan—based on their genes, health history, and other markers—helps them quit better than standard care. About 850 adult smokers from primary care clinics will take part. The goal is to see if this tailored approach …

This study is testing whether routine urine tests every 6 months for 2 years can find bladder cancer at an earlier stage in people at high risk. Participants must be 50 or older with a heavy smoking history or long-term exposure to certain workplace chemicals. The goal is to see …

This study compares two approaches to help adults stop using tobacco and lower their cancer risk. About 5,000 people who smoke will get either extra reminders and support or standard quit advice. The goal is to see which method leads to more people using medication, counseling, o…

This study looks at whether starting a quit attempt during the first half of the menstrual cycle (follicular phase) helps women stop smoking more successfully than starting during the second half or without cycle timing. About 1,200 women who smoke daily and have regular periods …

This study looks at whether adding low-dose CT scans for lung cancer to smoking cessation programs helps more people quit smoking. About 1,200 smokers aged 50-74 who smoke heavily will be split into groups to compare different methods. The goal is to see if the combination leads …

This study tests whether adding music therapy to nicotine replacement therapy (NRT) helps reduce cigarette cravings in student smokers aged 18 to 25. 120 participants will be randomly assigned to receive either NRT alone or NRT plus a digital music therapy tool. The goal is to se…

This study is developing a smartphone app that uses mindfulness techniques to help cancer survivors quit smoking. About 50 adults who have been diagnosed with cancer and smoke at least one cigarette a day will test the app. Researchers will measure how easy the app is to use and …

This study tests a friendly chatbot that uses motivational interviewing to help people stop smoking. The chatbot offers education, support, and a personalized quit plan. Researchers will check if it works by testing saliva for nicotine at 6 months. The study needs 440 adult smoke…

This study tests a counseling and education program designed to help Chinese and Korean American smokers quit smoking and improve their lung health. About 50 participants will receive the program and be followed for 6 months. The goal is to see if the program helps people stop sm…

This study aims to find the most effective approach to help people who both smoke cigarettes and use e-cigarettes (vape) quit smoking. 500 participants will try different combinations of treatments, like medication and nicotine patches, and be followed for a year. The goal is to …

This study looks at whether a type of talk therapy called Acceptance and Commitment Therapy (ACT) can help people with schizophrenia stop smoking and reduce their psychotic symptoms. About 90 adults with schizophrenia who smoke will take part. Researchers will use brain scans (fM…

This study tests whether nicotine pouches or nicotine mini lozenges help people smoke fewer cigarettes. About 300 adult smokers will use one of these products or no product for a week, then try to stop smoking for 3 weeks. Researchers will track how many cigarettes they smoke and…

This study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can help people with schizophrenia quit or reduce smoking. Fifty participants will receive active rTMS using either an F8 coil or an H coil. Researchers …

This study looks at whether cytisinicline, a drug used to help people quit smoking, can change how the brain responds to seeing smoking-related images. 64 daily smokers who are not trying to quit will take either the drug or a placebo and have their brain activity measured with a…

This study is for Veterans who smoke cigarettes and a support person they choose, like a family member or friend. The goal is to see if having that support person helps Veterans use proven quitting methods, such as medication or counseling. Researchers will track how much support…

This study aims to help Alaska Native and American Indian people quit smoking by tailoring their treatment based on how fast their body breaks down nicotine. About 50 participants will receive a personalized medication plan and be followed for 6 months. The goal is to see if this…

This study works with community organizations to understand why people have trouble quitting smoking and to design a better support program. Researchers will gather input from leaders and adults who smoke, then test a new treatment in a small group to see if it's practical and we…

This study aims to create a mobile health (mHealth) tool to help cancer patients stop smoking. Researchers will enroll 90 adult cancer patients who smoke to test if the tool is easy to use and acceptable. The goal is to build a resource that can be used by researchers across Flor…

This study tests a program that combines help with quitting smoking and getting lung cancer screening for African American smokers. About 250 people will take part. The goal is to see if this combined approach helps more people quit smoking and get screened, reducing health dispa…

This study aims to develop a smoking cessation program for pregnant women who have experienced trauma. Researchers will interview healthcare providers and pregnant women to understand their needs and improve support. The goal is to create a program that combines trauma-informed c…

This study is testing a program called CONNECTing to LungCare that helps smokers and their doctors have better conversations about quitting smoking and getting screened for lung cancer. The program provides education and a personalized summary to guide these discussions. Research…

This study tests a new way to help rural smokers who are not yet ready to quit. Paramedics will refer participants to a text-message program that encourages them to stop smoking. The goal is to see if this approach gets more people to engage and eventually quit.

This study collects blood, airway, and urine samples from up to 2,000 healthy volunteers and people with lung diseases like COPD and pulmonary fibrosis. Researchers will compare samples to establish normal ranges and learn how gene changes in airway cells may lead to disease. The…

This study looks at how romantic partners who both smoke can help each other quit. Researchers will ask 250 couples to fill out daily surveys for two weeks while trying to quit. The goal is to learn which types of support work best so future programs can help couples quit togethe…