Can a pill and patch help dual users kick the smoking habit?

NCT ID NCT06474299

Recruiting now Disease control Sponsor: University of Wisconsin, Madison Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a combination of varenicline (a pill) and nicotine patches can help people who both smoke cigarettes and use e-cigarettes quit smoking. About 500 participants will take the medications and be followed for 12 months to see if they stay smoke-free. The goal is to find the most effective approach for this group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: varenicline and nicotine patches
What this could lead to: If successful, this could identify the best combination of medications to help dual users quit smoking, reducing their health risks.
What could go wrong: This is a Phase 4 screening trial, so results are preliminary. The interventions may not work for everyone, and side effects like nausea or skin irritation are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Smoking Cessation Vaping

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ELECTRONIC CIGARETTE USE SMOKING CESSATION

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

University of Wisconsin-Madison School of Medicine and Public Health
RECRUITING

Madison, Wisconsin, 53792, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact

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