Routine urine tests could spot bladder cancer early in smokers and factory workers

NCT ID NCT05646485

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study is testing whether regular urine tests every 6 months can find bladder cancer earlier in people at high risk, such as smokers over 50 and those with long-term workplace chemical exposure. Researchers will enroll 1,000 participants and track how many cancers are detected. The goal is to develop a simple, non-invasive screening strategy for a cancer that currently has no standard screening method.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
urine test
What this could lead to
If successful, this could establish a simple, regular urine test as a standard way to catch bladder cancer early in high-risk people, potentially saving lives.
What could go wrong
This is an early-stage screening study, not a treatment trial. It may not prove that earlier detection improves outcomes, and false positives could cause unnecessary worry or procedures.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Texas Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

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Other studies related to the condition(s) this trial covers.