SMOKING CESSATION

This study aimed to check the long-term safety of a medication called cytisinicline, taken three times a day for a full year, to help people stop smoking cigarettes or vaping. It involved 479 people in the United States who had previously been in related studies and wanted to qui…

This study tested whether adding a medication called exenatide, which is used for diabetes, to standard nicotine patches could help people quit smoking more effectively. It also aimed to see if the medication could prevent the weight gain that often happens after quitting. The tr…

This study tested a medication called cytisine to help people who want to quit smoking and also have alcohol use disorder. It involved 20 adults and aimed to see if the drug was safe and effective for this group. The trial measured how well participants could stop smoking and man…

This study tested whether using magnetic pulses on the brain could help people quit smoking and avoid relapse. It involved 88 adult smokers who had previously failed to quit using standard medications. Researchers compared different patterns of brain stimulation to see which was …

This study tested two different programs to help cancer patients quit smoking. It compared an intensive program (12 weeks of medication plus 7 coaching calls) against a standard program (2 weeks of nicotine patches plus 3 calls). The goal was to see which approach was more effect…

This study tested a community-based program designed to help residents of Baltimore public housing quit or reduce smoking. The program provided free quit-smoking medications and counseling support delivered remotely to participants' homes. Researchers worked with community leader…

This study tested whether smokers who quickly cut their smoking in half using nicotine products like gum, patches, or e-cigarettes could keep using these alternatives to stay smoke-free or smoke less for six months. It involved 150 adult smokers who smoked at least 10 cigarettes …

This study tested QuitBet, a smartphone game designed to help people quit smoking using money as motivation. Participants who smoked at least 5 cigarettes a day bet $30 of their own money. Those who successfully quit smoking for the game period got their money back and split the …

This study tested whether letting cancer patients choose their own quit-smoking plan works better than having one randomly assigned. 126 patients with smoking-related cancers selected from 12 different combinations of medication, counseling, and nicotine replacement. Researchers …

This study tested a special therapy program designed to help people living with HIV quit smoking. The program focused on reducing anxiety and depression, which are common challenges that make quitting harder. Researchers compared this 9-session therapy to standard quit-smoking ad…

This study tested whether higher doses of nicotine patches and lozenges help people quit both cigarettes and e-cigarettes. Researchers worked with 46 adults in South Carolina who regularly used both products and wanted to quit. They compared three different dose levels to see whi…

This small pilot study tested a new support system called 'Nudges to Quit' to help people with serious mental illness stop smoking. The program used reminders to encourage patients, case workers, and pharmacists to connect and use proven quit-smoking treatments. The goal was to s…

This small, completed study tested a new approach to help heavy smokers quit. It combined standard nicotine patches with a gentle, non-invasive brain stimulation technique called rTMS. The goal was to see if stimulating a specific brain area could reduce cravings in people who ha…

This study tested a more involved, ongoing support program for quitting smoking against the usual yearly offer of help. It involved 979 primary care patients who smoke and lasted 18 months. The main goal was to see which approach led to more people successfully quitting and if th…

This study tested whether a medication called cytisinicline could help adult smokers quit. Over 800 participants who smoked at least 10 cigarettes a day and wanted to quit were randomly assigned to receive either the real medication or a placebo (a dummy pill) for either 6 or 12 …

This study tested a new approach to help cancer patients quit smoking before their surgery. Half of the 282 participants received this novel treatment, while all received standard support including counseling and nicotine patches. The goal was to see if the extra help improved qu…

This study tested whether a telephone-delivered program using guided imagery could help people quit smoking more effectively than standard behavioral support. Over 1,200 daily smokers from three states received coaching calls and nicotine patches. The main goal was to see if the …

This study tested four different support programs to find the most effective way to help underserved smokers quit for at least six months. It involved over 3,200 current smokers from Black, Hispanic, low-income, or rural communities who were already scheduled for a lung cancer sc…

This study tested a new mobile app designed to help people quit smoking. The app used a psychological approach called 'cognitive dissonance,' where people create videos about their commitment to quit and share them in a small online support group. Researchers wanted to see if thi…

This study tested a smartphone-based program to help adult smokers who also use other nicotine products (like vapes or pouches) completely switch away from cigarettes. 105 participants used an app with a breath sensor and text coaching for 26 weeks. The main goal was to see how m…

This study tested four different health system strategies to connect more primary care patients who smoke daily with proven quit-smoking treatments, even if they weren't ready to quit at the start. Over 1,600 adult patients were enrolled for two years to see if methods like finan…

This study tested whether a medication called d-cycloserine could help smokers switch completely from regular cigarettes to a Juul e-cigarette. Researchers worked with 25 adult smokers who wanted to make this switch, using the medication alongside a behavioral strategy. The main …

This study tested if mailing free samples of quit-smoking medications directly to people helps them stop or cut down on smoking. Over 650 daily smokers were randomly chosen to receive either a sample of varenicline (Chantix), nicotine patches and lozenges, or no sample at all. Re…

This study tested whether a medication called cytisinicline could help adults quit smoking. Nearly 800 daily smokers who had previously tried to quit took either the medication or a placebo pill for 6 or 12 weeks, along with behavioral support. Researchers measured how many peopl…

This study tested whether two prescription medications, zonisamide and bupropion, could help smokers completely switch from regular cigarettes to a JUUL e-cigarette. 180 adult smokers who wanted to switch were given the e-cigarette and then randomly assigned to receive either bot…

This study tested whether a new smartphone app called OKquit could help people quit smoking when added to standard support from a state helpline. Researchers enrolled 512 adults in Oklahoma who wanted to quit and randomly assigned them to receive either standard helpline care or …

This study tested a new, personalized approach to help people who recently quit smoking stay smoke-free. Researchers first identified different types of ex-smokers, then created custom counseling and text messages for each type. The goal was to see if this tailored support was pr…

This study tested whether receiving supportive text messages through WhatsApp could help people who recently quit smoking avoid starting again. Researchers enrolled 590 adults in Hong Kong who had stopped smoking for 3-30 days. Half received regular encouraging messages through t…

This study tested two approaches to help public housing residents follow smoke-free rules and reduce secondhand smoke exposure. Researchers worked with 405 residents in New York City public housing buildings. They tried both community-wide encouragement and targeted help for smok…

This pilot study tested whether a digital chatbot could provide helpful counseling to support young smokers trying to quit. Researchers enrolled 154 young smokers in Hong Kong to see if they would use the chatbot and stick with the program for six months. The goal was to check if…

This small pilot study tested a program designed to help cancer survivors quit smoking and better manage their pain. The program combined counseling techniques with a prescription medication (varenicline/Chantix) that can aid both smoking cessation and pain relief. Researchers ai…

This study tested two different counseling approaches to help people with HIV quit smoking. Researchers compared traditional smoking cessation counseling with a newer method called behavioral activation problem solving (BAPS). Both approaches involved phone sessions over several …

This small pilot study tested a video-based program designed to help cancer patients quit smoking. Researchers wanted to see if patients found the videos helpful and easy to use, and if they increased knowledge about quitting. The goal was to gather information before launching a…

This study aimed to find out which nicotine replacement products menthol smokers prefer when trying to quit. 60 African American adults who regularly smoked menthol cigarettes tried different flavored and unflavored nicotine gums and inhalers. After sampling the products for two …

This study tested whether a prescription sleep medication called suvorexant could help people quit smoking by reducing cravings, withdrawal symptoms, and stress. It involved 14 adults with tobacco use disorder who were not actively seeking treatment. Researchers measured stress, …

This study tested whether motivational interviewing, delivered through online video calls, could increase the desire to quit smoking in people diagnosed with lung cancer. It involved 42 adult patients who were current smokers. Researchers measured changes in their intention to qu…

This small pilot study tested whether using chewing gum could help people smoke fewer cigarettes or quit smoking altogether. Researchers in Hong Kong enrolled 80 adult smokers who wanted to quit or cut down. They compared one group that used chewing gum for a week to another grou…

This small pilot study tested a new smartphone app designed to help people living with HIV quit smoking. The app, called SiS-H, combined quitting strategies with support for staying positive and managing HIV care. Researchers compared it to an existing quit-smoking app to see if …

This study looked at whether certain blood cell mutations, called CHIP, are linked to continued heart problems in people who have had a heart attack, even after they quit smoking. Researchers followed 1,029 patients who had a procedure to open their heart arteries. They checked p…

This study aimed to understand if stress affects smoking behaviors differently for African American and white men. Researchers compared 95 male smokers from these two groups, measuring their stress responses and daily smoking habits. The goal was to gather knowledge that could he…

This study aimed to understand if the nicotine level in e-cigarette liquid affects how much people puff and their ability to switch completely from smoking cigarettes. Researchers compared high and low nicotine e-liquids in 52 adult African American and white smokers. They measur…