SMOKING CESSATION

This study tested a simple approach: giving adult smokers who came to the emergency department an e-cigarette starter kit and a referral to stop-smoking services. Researchers compared their quit rates to those who received usual care. The goal was to see if this brief interventio…

This study tested a telephone-based guided imagery program called Be Smoke Free to help people quit smoking. Over 1,200 daily smokers from Arizona, New York, and West Virginia took part. Participants received coaching calls and were checked at 3 and 6 months to see if they had st…

This study tested a simple tool that helps doctors choose the right medicines to help people with HIV stop smoking. 371 participants who smoked at least 5 cigarettes a day took part. The tool aimed to increase the number of people who quit smoking for at least 7 days.

This study compared four different programs to help underserved smokers quit smoking for at least 6 months. Over 3,200 participants who were referred for lung cancer screening took part. The goal was to find the most effective approach to help them stop smoking and improve their …

This study tested whether a hospital-based smoking cessation program could help smokers quit after they leave the hospital. Over 1,100 adult smokers from several hospitals took part. The program offered extra support and medication to help them stop smoking.

This study looked at whether smokers who quickly reduce their cigarette use with nicotine products (like patches, e-cigarettes, or pouches) can keep up that progress for 6 months. 150 healthy adult smokers who cut smoking by at least half in the first 2 weeks were followed. The g…

This study looked at two approaches to help residents in public housing buildings follow smoke-free policies. One approach encouraged all residents to support the rules, while the other focused on helping smokers reduce or quit smoking. The goal was to lower secondhand smoke expo…

This study tested a program called Comprehensive Chronic Care (CCC) to help smokers quit. About 979 adults who smoke daily took part. The program was compared to standard care to see if more people stayed smoke-free after 18 months.

This study tested a new type of counseling called BAPS to help smokers with HIV quit. 651 participants were split into two groups: one received standard smoking cessation counseling, the other received BAPS. The goal was to see which approach led to more people quitting smoking b…

This study looked at different ways to encourage adult smokers to use proven quit-smoking treatments. Over 200 participants received offers like free counseling, nicotine patches, or financial incentives. The goal was to see which methods helped more people start treatment and ev…

This study tested a tool called a Volitional Help Sheet to help young adults aged 20-45 in Indonesia stop smoking. Researchers gave the worksheet to 2700 smokers to see if it helped them quit. The main goal was to see if people stopped smoking, and the study also looked at nicoti…

This study looked at the long-term safety of a drug called cytisinicline for helping people quit smoking or vaping. 479 adults who had already been in earlier studies took the drug three times a day for 52 weeks. Researchers tracked serious side effects and other health changes t…

This study tested a new counseling method to help people who recently quit smoking stay smoke-free. Researchers worked with 100 ex-smokers and their counselors to see if the approach was practical and liked by users. Early results suggest the method may help reduce relapse, but m…

This study tested a program to help people with lung cancer stop smoking. Researchers worked with 263 patients to provide support and medication. The goal was to see if the program could help more patients quit and improve how doctors document tobacco treatment.

This study tested whether two medications, zonisamide and bupropion, can help smokers switch completely to using an e-cigarette (JUUL) instead of regular cigarettes. 180 adult smokers who wanted to switch took part. They all received a JUUL and were randomly assigned to get eithe…

This study tested whether giving cancer patients a say in their smoking cessation treatment helps them quit more effectively. 126 patients with tobacco-related cancers were allowed to choose from a mix of counseling, medication, and nicotine replacement. The goal was to see if pe…

This study tested two different smoking cessation programs in 52 adults diagnosed with cancer in the past 3 years. One group received 12 weeks of medication and 7 coaching calls focused on cancer, while the other received a standard 2-week nicotine patch and 3 coaching calls. The…

This study tested how different nicotine levels in e-cigarettes change the way people puff and whether they switch from smoking to vaping. 52 Black and White smokers who wanted to switch used e-cigarettes for 6 weeks. Researchers measured puffing, nicotine intake, and how many pe…

This study tested whether a mobile chat messaging program could help people who recently quit smoking avoid going back to cigarettes. 590 adults in Hong Kong who had been smoke-free for 3 to 30 days took part. They received support through WhatsApp to help them stay on track. The…

This study tested a smartphone app called SiS-H (Smiling Instead of Smoking for people with HIV) to help people with HIV quit smoking. 66 participants were split into two groups: one used the SiS-H app, the other used a standard quit-smoking app. The goal was to see if the new ap…

This study tested whether offering rewards (contingency management) helps cancer patients quit smoking before surgery. All 282 participants received standard counseling and nicotine patches; half also got the reward program. The goal was to see if rewards boost abstinence rates, …

This study tested whether cytisine, a plant-based medication, is safe and helpful for quitting smoking in people who also have alcohol use disorder. Twenty adults who smoked daily and had alcohol problems took cytisine and were monitored for side effects and smoking abstinence. T…

This study tested whether caregivers of hospitalized children would use a smoking cessation program. Participants received a 20-minute counseling session and nicotine patches and lozenges for two weeks. The goal was to see if the program was helpful and could be offered hospital-…

This study tested whether a medication called d-cycloserine can help smokers switch from regular cigarettes to e-cigarettes by making it easier to learn new habits. 25 adult smokers who wanted to switch participated. The study used a reward devaluation strategy combined with the …

This study tested a video program to help cancer patients stop smoking. 42 adults with cancer who smoked took part. Researchers wanted to see if patients liked the videos, if the program was easy to use, and if it helped them learn more about quitting. The goal is to gather infor…

This study tested a smartphone app called OKquit to help smokers quit. Over 500 adults who called the Oklahoma Tobacco Helpline took part. Some got the app plus standard help like nicotine patches, while others got standard help only. The app provided on-demand tips and daily che…

This pilot study tested whether low-frequency repetitive transcranial magnetic stimulation (rTMS) to a specific brain area could reduce cravings in heavy smokers who had failed multiple quit attempts. 39 highly nicotine-dependent adults received rTMS alongside nicotine replacemen…

This study tested whether mailing free samples of varenicline (a prescription pill) or nicotine patches and lozenges helps smokers quit. 652 daily smokers were randomly assigned to receive a free sample of varenicline, nicotine products, or no sample. Participants completed surve…

This study tested a pill called cytisinicline in 792 adult smokers who wanted to quit. Participants took the pill or a placebo for either 6 or 12 weeks. The main goal was to see if the pill helped them stop smoking, confirmed by breath tests. The results could offer a new option …

This study tested a friendly healthbot designed to help people remember to take their smoking cessation medication (varenicline). Researchers interviewed smokers and healthcare providers to understand challenges, then built a chatbot. 40 participants used the bot for 12 weeks, an…

This study tests whether a non-invasive brain stimulation technique called TMS can help people quit smoking and avoid relapsing. About 88 adult smokers who have tried and failed to quit before will receive either real or fake TMS sessions, first daily then weekly, to reduce cravi…

This study tested whether higher doses of nicotine patches and lozenges can help people quit both cigarettes and e-cigarettes at the same time. 46 adults who smoked and vaped daily took part. Researchers measured how many days they stayed away from both products and checked for s…

This study tested a smartphone game called QuitBet that helps people stop smoking. Players put $30 of their own money into a pot. Those who meet their no-smoking goal split the pot, getting their money back plus extra from those who didn't succeed. The study involved 245 adults w…

This study tested a special counseling program to help people living with HIV quit smoking. The program focused on reducing anxiety and depression, which often make it harder to stop smoking. 131 smokers with HIV took part to see if this approach helped them quit and stay smoke-f…

This study tested whether suvorexant, a drug used for sleep, could help smokers manage cravings and stress that often lead to relapse. Fourteen non-treatment-seeking smokers took part in this small Phase 2 trial. Researchers measured stress, heart rate, and smoking behavior to se…

This study tested whether chewing gum can help people cut down on cigarettes or quit smoking. 80 smokers in Hong Kong were split into two groups: one received chewing gum and brief advice, the other only advice. The goal was to see if gum chewing led to fewer cigarettes smoked an…

This study tested a smartphone-based program to help adult smokers who also use smoke-free nicotine products (like e-cigarettes or nicotine pouches) completely stop smoking cigarettes. About 105 participants who had tried and failed to quit before used the app to track their prog…

This study tested a program to help cancer survivors quit smoking and manage pain. Nineteen survivors joined the program, which included counseling and support. The goal was to see if the program was practical and helpful for participants.

This study tested a mobile app designed to help people quit smoking by using a technique called cognitive dissonance — making smokers feel the conflict between wanting to be healthy and continuing to smoke. 72 adult daily smokers who wanted to quit used the app for 25 days. Resea…

This study tested a gentle brain stimulation method called tDCS to see if it could help cancer survivors who smoke feel less distressed and smoke fewer cigarettes. 43 participants used the device at home via telehealth. The main goal was to see if the device was easy and comforta…

This study tested a pill called cytisinicline to help adults stop smoking. Over 800 daily smokers took either the pill or a placebo for 6 or 12 weeks. The goal was to see if the pill helped them stay smoke-free, verified by breath tests. The study is complete and aims to provide …

This study tested a smartphone app designed to help people quit smoking. Over 500 adults who smoked daily used the app to track their progress and get support. The goal was to see if the app could help them stop smoking for good.

This study tested whether online video conversations with a counselor could increase the desire to quit smoking in people with lung cancer. 42 patients who smoked took part. The approach used motivational interviewing, a supportive talk method, to strengthen their intention to qu…

This pilot study tested whether a text-based reward program could help 20 adults stick with smoking cessation counseling and medication. Participants received texts encouraging them to complete quitline calls and take varenicline pills. The goal was to see if this approach is fea…

This study tested whether exenatide, a drug used for diabetes, can help people quit smoking and avoid gaining weight after they stop. About 140 adults who smoked at least 5 cigarettes daily and wanted to quit took part. They received either exenatide or a placebo alongside a nico…

This study tested a chatbot designed to help young smokers (aged 25 or younger) quit tobacco. Over 150 participants used the chatbot on their smartphones. Researchers checked how many joined, stayed in the study, and found the chatbot helpful, and measured if they actually quit s…

This study looked at whether teaching smokers to think in a big-picture way (high-level construal) can help them quit. It involved 300 low-income adults aged 25-55 who had tried to quit before. Researchers used brain scans and surveys to understand how this thinking style affects…

This study looked at healthy women aged 30 to 60 who either started intermittent fasting (eating only during an 8-hour window) or quit smoking. Researchers checked if these lifestyle changes could improve DNA markers linked to aging and cancer risk over 6 months. Participants rec…

This study tested a new smoking cessation program for residents of Baltimore City public housing. The program combined remote support from specialists, access to quit-smoking medications, and on-site community leaders to help smokers reduce or quit. The goal was to see if this ap…

This study looked at what kinds of nicotine replacement products menthol smokers like best when trying to quit. 60 African American adults who smoked menthol cigarettes tried six different products, including mint and non-mint gums and inhalers. After two weeks of trying them, th…

This study looked at 1029 people who had a heart attack and quit smoking. Researchers checked if a common, often harmless blood condition called CHIP (clonal hematopoiesis) makes heart problems more likely even after quitting. The goal was to understand why some former smokers st…

This study looked at how stress and smoking habits differ between African American and white male smokers. Researchers measured stress responses using a psychological test and tracked daily cortisol patterns. The goal was to understand biological and social factors that influence…

This pilot study tested a program called 'Nudges to Quit' that aimed to help people with serious mental illness stop smoking. The program used gentle reminders from case workers and pharmacists to encourage patients to try tobacco treatment. The study included 59 adult smokers an…