Free samples of Quit-Smoking drugs mailed to your door: does it work?

NCT ID NCT04525755

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether mailing free samples of varenicline (Chantix) or nicotine patches and lozenges helps smokers quit. 652 daily smokers were randomly assigned to receive a one-time sample of varenicline, nicotine replacement products, or no medication. Participants were not required to quit or use the samples. The study lasted 6 months and tracked smoking habits through surveys and daily diaries.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
varenicline (Chantix) and nicotine replacement therapy (patches and lozenges)
What this could lead to
If successful, this approach could make it easier for smokers to try quitting by offering free medication samples remotely, potentially increasing quit rates.
What could go wrong
This is an early-phase study with a relatively small sample. The results may not apply to all smokers, and participants were not required to quit, so the true effect on quitting is uncertain.

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Conditions

The condition(s) this trial relates to.

Cigarette Smoking Smoking Smoking Cessation Tobacco Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

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