CIGARETTE SMOKING

This study is testing whether offering smokers who aren't ready to quit a choice of alternative nicotine products (like e-cigarettes, heated tobacco, or nicotine pouches) helps them reduce or stop smoking cigarettes. Participants will receive a 4-week supply of their chosen produ…

This study is testing whether tobacco-free nicotine pouches can help people switch from smoking cigarettes. Researchers will give 50 adult smokers either low or high nicotine pouches to use for 4 weeks instead of cigarettes. They'll track how many people completely switch, reduce…

This study is testing if a weekly injection called semaglutide can help adults who are quitting smoking avoid gaining weight. Researchers want to see if the medication helps control appetite and food intake during the challenging period after stopping cigarettes. The trial will e…

This study aims to see if providing free e-cigarettes is more effective than counseling and nicotine patches at helping people who smoke and have opioid use disorder reduce their cigarette smoking. It will enroll 302 adults who are in treatment programs for opioid use and smoke a…

This study aims to see if e-cigarettes or oral nicotine pouches can help persistent cigarette smokers switch away from smoking. Researchers will enroll 200 adult smokers who have tried to quit before and randomly assign them to use one of these alternatives for 6 weeks. The main …

This study tests whether switching medications early can help smokers who struggle to quit. Participants receive free quit-smoking products for 12 weeks, and the treatment plan adjusts based on their initial progress. The study is conducted entirely remotely with 544 smokers acro…

This study is testing whether the flavor of an e-cigarette makes it easier for long-term smokers to switch from regular cigarettes. Researchers will give 210 persistent smokers either fruit, tobacco, or menthol flavored e-cigarettes to use for six weeks instead of smoking. The go…

This study is testing two different ways to help people with serious mental illnesses, like schizophrenia or bipolar disorder, reduce their cigarette smoking. Participants will receive counseling and text message support, plus either e-cigarettes or nicotine patches/lozenges. The…

This study is developing and testing a mobile phone app designed to help young adults quit or reduce their use of e-cigarettes (vaping). Researchers at the University of Chicago are recruiting 46 people aged 18-26 who vape frequently and want to cut back. The goal is to see if th…

This study aims to understand how making cigarettes very low in nicotine, along with changes in e-cigarette and illegal cigarette prices, might affect what people buy. Researchers will use a virtual marketplace to see if these policies lead to more purchases of illegal cigarettes…

This study aims to understand how THC, the main active ingredient in cannabis, affects a person's desire to smoke cigarettes and their actual smoking behavior. Researchers at Johns Hopkins will give 100 adult participants who regularly use both cannabis and cigarettes different d…

This study aims to understand if relighting a cigarette produces more harmful chemicals than smoking it without stopping. Researchers will observe 30 adult smokers who regularly relight cigarettes, measuring the smoke they produce and asking about their experience. The goal is to…

This study aims to understand how different tax proposals on cigarettes and other tobacco products might change what smokers choose to buy. Researchers will use a virtual marketplace to see how over 300 daily smokers spend a budget when faced with four different tax plans. The go…