Zapping the brain to kick the habit: new trial tests rTMS for smoking cessation

NCT ID NCT04903028

Recruiting now Symptom relief Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a non-invasive brain stimulation technique called rTMS can help people stop smoking. Researchers will use MRI scans to guide the stimulation to brain areas involved in craving and self-control. The trial involves 64 smokers who will receive either real or sham rTMS, and their quit rates and brain activity will be measured over several weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: repetitive transcranial magnetic stimulation (rTMS)
What this could lead to: If successful, this could offer a non-drug, brain-based approach to help people quit smoking by reducing cravings and improving self-control.
What could go wrong: This is an early-stage study with only 64 participants, so results may not apply to everyone. The treatment is non-invasive but may cause mild side effects like headache or scalp discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cigarette Smoking nicotine dependence Smoking Cessation Tobacco Use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CIGARETTE SMOKING TOBACCO USE

Contacts and locations

Locations

Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States
Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States

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