Brain scans reveal how common drugs may dull smoking urges
NCT ID NCT05587361
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how the drug propranolol and nicotine patches, alone or together, change brain activity and cravings when smokers see smoking-related cues. Eighty daily smokers will undergo brain scans while viewing these cues. The goal is to understand the brain mechanisms behind smoking urges, not to help participants quit.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Propranolol and nicotine patch
What this could lead to
If successful, this could reveal how these medications change brain activity related to smoking urges, potentially guiding future treatments for nicotine dependence.
What could go wrong
This is an early-stage experimental study with only 80 participants, not designed to test a treatment. Results may not translate to real-world smoking cessation.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hardesty Center for Clinical Research and Neuroscience
RECRUITINGTulsa, Oklahoma, 74136, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••