New study lets smokers choose their own path to quit

NCT ID NCT07199517

Recruiting now Disease control Sponsor: Abramson Cancer Center at Penn Medicine Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for people who smoke cigarettes but aren't ready to quit. It tests whether giving them a choice of harm-reduction products like e-cigarettes or nicotine pouches helps them smoke less or stop altogether. Participants will use their chosen product for 28 days and be followed for 6 months to see if they cut down or quit smoking.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: e-cigarettes, nicotine pouches, nicotine patches, and nicotine lozenges
What this could lead to: If successful, this approach could help smokers who aren't ready to quit reduce their cigarette use or even stop smoking entirely.
What could go wrong: This is a behavioral study, not a drug trial, so results may vary widely. Participants might not stick with the products, and long-term health effects of e-cigarettes or nicotine pouches are still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cigarette Smoking Harm Reduction nicotine dependence Tobacco Use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CIGARETTE SMOKING CIGARETTE SMOKING BEHAVIOR TOBACCO USE

Contacts and locations

Locations

University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

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