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Can E-Cigs help smokers with mental illness cut down?

NCT ID NCT05815199

Recruiting now Disease control Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two approaches to help people with serious mental illness reduce their cigarette smoking: using e-cigarettes or nicotine patches and lozenges, combined with counseling. Sixty participants who smoke at least 5 cigarettes a day will be randomly assigned to one of the two groups. The goal is to see which method leads to a greater reduction in smoking over 8 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
e-cigarette (NJOY Ace) and nicotine replacement therapy (patch and lozenges)
What this could lead to
If successful, this could show that e-cigarettes are a more effective harm-reduction tool than nicotine patches for people with serious mental illness who smoke.
What could go wrong
This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. The study relies on self-reported smoking, which can be inaccurate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cigarette Smoking Harm Reduction Vaping

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CIGARETTE SMOKING

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

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