Nyu Langone Health

This study tests whether a smartphone app can help people reduce their use of illegal opioids while they are in treatment for opioid addiction. The app uses a short test to predict the chance of relapse in the next week and adjusts medication doses accordingly. About 225 adults w…

This study tests whether a blood test that measures immune protection against a common virus (CMV) can safely shorten the time lung transplant recipients need to take antiviral medication. About 50 participants will have their antiviral treatment duration guided by the test resul…

This study compares two types of knee implants (medial congruent vs. posterior stabilized) in people having total knee replacement for arthritis. All surgeries will be done with the ROSA robotic system. Researchers will track 200 participants for up to 5 years to see which implan…

This study tests a new drug called elacestrant, combined with two standard biologic therapies, in people with advanced triple positive breast cancer (ER+, PR+, HER2+). The goal is to see if the combination can slow or stop cancer growth. About 50 women aged 18 and older will take…

This study tests a drug called DRP-104 in people with advanced non-small cell lung cancer that has specific gene changes (NFE2L2 or KEAP1). The drug works by blocking glutamine, a nutrient cancer cells need to grow. The trial aims to see if the drug can shrink tumors or slow the …

This study looks at why some people diagnosed with diabetes in the emergency room don't follow up with a regular doctor. Researchers will test whether a telehealth visit soon after diagnosis helps patients get connected to outpatient care. The trial involves 200 adults in New Yor…

This study tests whether using a catheter to remove blood clots from the lungs, along with standard blood thinners, helps people with submassive pulmonary embolism recover better than blood thinners alone. About 500 adults with large clots and an enlarged right heart chamber will…

This study tests two ways to help Chinese immigrants with type 2 diabetes control their blood sugar: watching educational videos, or videos plus a community health worker. 540 adults in NYC will join. The goal is to see if these tools lower HbA1c levels and boost confidence in ma…

This study tests whether adding financial coaching to standard smoking cessation counseling helps low-income smokers quit. 602 participants will receive either standard counseling or integrated financial-smoking counseling, plus nicotine patches. The goal is to see if addressing …

This study tests whether placing a cochlear implant's ground electrode near the vagus nerve behind the ear works as well as the standard placement under a muscle. Twelve adults getting a cochlear implant will participate. The main goal is to see if speech understanding in noise i…

This study tests whether a simple blood test that looks for tumor DNA (ctDNA) can help doctors decide when to add a third immunotherapy drug (ipilimumab) to a two-drug combination (nivolumab and relatlimab) for people with advanced melanoma. About 90 adults with metastatic or adv…

This pilot study is testing whether a noninvasive brain stimulation device, used at home along with guided mindfulness, can help people with cannabis use disorder reduce their use. Forty-six adults who want to cut back on cannabis will receive either real or sham stimulation over…

This study tests whether an AI-enhanced digital tool called iMatter2 can help people with type 2 diabetes better manage their condition. About 353 participants will use the tool to report their symptoms and receive feedback, while researchers track changes in blood sugar levels o…

This pilot study tests whether giving a blood thinner (rivaroxaban) and a high-dose statin (atorvastatin) to adults who had heart injury after noncardiac surgery can reduce future heart problems. The study will enroll 50 people aged 45 and older to see if this approach is feasibl…

This study tests whether giving magnesium sulfate soon after a cardiac arrest can protect the brain from damage. Researchers will give 178 patients either magnesium or a saltwater solution within two hours of their heart restarting. The main goal is to see if the treatment is saf…

This study tests whether pregnant women at high risk for fetal heart block can use a home monitor to catch early signs of the condition. If detected, they receive steroids and IVIG to try to reverse the block before it becomes permanent. The goal is to prevent stillbirth and the …

This study tests whether an 8-week culturally responsive harm reduction program helps Black and Latinx people who use drugs engage more with services and reduce opioid or stimulant use. Researchers will compare the program to standard harm reduction services in 200 participants. …

This study tests a new way to deliver radiation for intermediate-risk prostate cancer. Using an MRI machine that also delivers radiation, doctors can give a higher dose to the main tumor while lowering the dose to the rest of the prostate. The goal is to improve tumor control and…

This study compares e-cigarettes to standard counseling and nicotine patches/lozenges for reducing smoking in people with opioid use disorder. About 300 participants who smoke at least 5 cigarettes daily and are in treatment for opioid addiction will be followed for 6 months. The…

This study tests whether weekly diabetes education videos sent by text message, plus help from a community health worker, can improve blood sugar control in Chinese immigrants with type 2 diabetes. 270 participants in New York City will be randomly assigned to receive the program…

This study tests whether improving nutrition before surgery reduces complications in people with inflammatory bowel disease (IBD). About 150 adults scheduled for intestinal surgery will receive a nutrition specialist and special shakes. Researchers will track hospital stay length…

This study compares standard ACL reconstruction using a bone-tendon-bone graft to the same surgery with an added internal brace. The goal is to see if the brace improves knee stability and healing. Researchers will enroll 90 people aged 18 to 35 who need ACL surgery. Participants…

This study tests whether taking a daily probiotic capsule (Lactobacillus rhamnosus GG) for six weeks after surgery can improve immune markers and recovery in people treated for a hip or knee joint infection. About 152 adults aged 18–90 will be enrolled. Researchers will measure b…

This study tests a program where trained peers deliver blood pressure medications directly to patients' homes and use health technology to support adherence. The goal is to see if this approach helps people with uncontrolled high blood pressure take their pills regularly and lowe…

This study compares standard meniscal repair surgery with and without the BEAR implant, a collagen-based scaffold that may help the torn meniscus heal better. Researchers will track knee function, pain, and repair failure in 80 participants over time. The goal is to see if adding…

This study looks at whether people aged 60 and older with stable lupus can safely stop taking hydroxychloroquine, a common medication that can cause eye damage over time. About 330 participants will either continue the drug or switch to a placebo and be monitored for one year. Th…

This study tests whether using portable air filters at home can improve the health of people with heart failure. Researchers will measure how far participants can walk in six minutes, along with blood pressure and heart-related blood markers. The study involves 255 adults in Indi…

This early-phase trial is testing a new way to deliver radiation for low-to-intermediate risk prostate cancer. Instead of many sessions, it uses just two high-dose treatments, with an extra boost to the main tumor. The goal is to see if this approach is safe and feasible for abou…

This study looks at whether helping clinics offer more take-home doses of methadone (instead of daily visits) helps people stay in treatment for opioid use disorder. Researchers will work with 36 clinics and about 318 patients to see if this approach reduces emergency visits and …

This phase 2 trial is for men with unfavorable intermediate-risk prostate cancer. Participants choose between standard care (6 months of hormone therapy plus high-dose radiation) or radiation alone. The goal is to see if skipping hormone therapy still keeps cancer from returning.…

This phase 2 trial tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) can help people with opioid use disorder who continue using illicit opioids even while on methadone. Up to 480 participants will receive either a low (1 mg), medium (20 mg), or…

This study tests whether adding the drug sarilumab to a standard immunotherapy combination can reduce severe side effects and work better for people with advanced melanoma that cannot be removed by surgery. About 105 participants will receive sarilumab along with ipilimumab, nivo…

This study tests whether people with HPV-positive throat cancer can safely receive a lower dose of radiation if their tumor shrinks quickly during early treatment. About 120 participants will be monitored for 2 years to see if the reduced treatment still prevents cancer from comi…

This early-stage trial tests a drug called CpG1018, which aims to stimulate the immune system to fight Alzheimer's disease. It involves 18 people with mild cognitive impairment or mild Alzheimer's. The main goal is to check safety, not yet to see if it works.

This early-phase trial tests an experimental drug called XRD-0394 combined with radiation therapy in 39 people with high-grade glioma, an aggressive brain cancer. The drug is designed to make radiation more effective at killing tumor cells. The main goal is to find a safe dose an…

This early-stage trial is testing whether adding ladarixin to the standard drug sotorasib can help people with advanced KRAS G12C mutant non-small cell lung cancer. About 40 adults whose cancer has spread or cannot be removed will receive both pills daily. The study will first ch…

This study looks at whether time-restricted eating (eating only during a set window each day) can help adults who have recently lost weight keep it off and avoid regaining fat. About 110 adults aged 25-65 who lost at least 5% of their body weight in the last 3 months will be rand…

This study tests whether the shingles vaccine (Shingrix) is safe and triggers a good immune response in people with lupus, a condition that affects the immune system. About 224 adults with lupus will receive either the vaccine or a placebo, and researchers will monitor for lupus …

This study tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) combined with therapy can change brain activity and reduce drinking in people with alcohol use disorder. Two hundred participants will receive either psilocybin or a placebo, plus supp…

This study tests whether transplanting a face and hands together can help people with severe injuries that standard surgery and prosthetics cannot fix. Ten adults aged 18-64 will receive the transplant and be monitored for changes in function and appearance using tests like EMG, …

This study tests whether combining remote blood pressure monitors with support from community health workers helps Latinx patients better manage their high blood pressure. About 300 adults with uncontrolled hypertension will take part. The goal is to see if this approach lowers b…

This study tests whether belatacept, an anti-rejection medication, is safe for adults who have just received a new heart. About 12 participants will receive the drug and be monitored for serious complications like rejection, infection, or organ failure. The goal is to find a bett…

This study tests whether empagliflozin, a diabetes medicine, is safe and helps control body fluid levels in 60 adults who are starting hemodialysis for end-stage kidney disease. Participants will take either empagliflozin or a placebo for 12 weeks. The goal is to see if the drug …

This early-phase study tests whether adding a heat-based treatment (radiofrequency ablation) to chemotherapy is safe for people with advanced pancreatic cancer that hasn't spread to other organs. About 15 participants will receive the procedure through an endoscope guided by ultr…

This study is testing whether a hand transplant from a deceased donor can help people who have lost part or all of one or both hands and forearms regain better function, appearance, and feeling. Participants will receive the transplant surgery and be followed closely with exams, …

This study tests an auditory brainstem implant in 20 children who are deaf because they are missing the inner ear or the nerve that carries sound to the brain. The device is surgically placed to stimulate the brainstem directly, bypassing the missing parts. Researchers will monit…

This study compares two approaches to help people with serious mental illness reduce their cigarette smoking: using e-cigarettes or nicotine patches and lozenges, combined with counseling. Sixty participants who smoke at least 5 cigarettes a day will be randomly assigned to one o…

This study tests whether using portable air cleaners with HEPA filters at home can lower blood pressure in adults with hypertension living in New York City public housing. Fine particle air pollution is linked to high blood pressure, and these devices aim to reduce indoor exposur…

This study looks at whether wearing a continuous glucose monitor (CGM) for two weeks after leaving the hospital helps people with diabetes who are starting insulin for the first time. About 150 adults with type 1 or type 2 diabetes will be randomly assigned to use either a CGM or…

This study tests a procedure called a CD34+ selected donor cell boost for people whose stem cell transplant has not worked well (graft failure or poor function). The donor's blood stem cells are separated using a special system and then infused back into the patient to help resto…

This study tests whether starting a monthly extended-release buprenorphine injection (Sublocade) in jail helps people with opioid use disorder stay on treatment after release. Two hundred men entering jail with a daily buprenorphine prescription will be randomly assigned to eithe…

This study is looking for biomarkers—clues in the body—that could help find lung cancer early. Over 3,600 participants, including people at high and low risk for lung cancer, will provide samples and undergo CT scans. The goal is to see if these biomarkers can spot tumors before …

This study tests a modified MRI technique designed to reduce image distortion caused by metal hip implants. Researchers will compare standard and modified scans in 22 adults with hip replacements to see if the new method provides clearer pictures of nearby tissues. The goal is to…

This study will test whether a special type of scan called PSMA PET/MRI can find prostate cancer that comes back after a treatment called High-Intensity Focused Ultrasound (HIFU) better than a standard MRI. About 60 men who had HIFU for prostate cancer will get both scans one yea…

This study tests a two-level train-the-trainer model to scale up a mental health program for teachers in Ugandan schools. The program, called mWEL-PD, trains teachers to support their own wellbeing and that of their students. Researchers will compare this new model with and witho…

This study is testing a mobile health toolkit called mWEL to help teachers and caregivers in Uganda manage stress and prevent depression and anxiety. The app screens for mental health issues, gives personalized feedback, and offers coping strategies. Researchers will enroll 1,180…

This study is testing a program called ROSE, which includes six group sessions and one individual session for pregnant women. The goal is to see if it can prevent postpartum depression, reduce stress, and increase social support. About 308 pregnant women receiving care at a speci…

This study tests whether the drug guselkumab can prevent psoriatic arthritis in people with psoriasis who are at high risk. 176 adults with psoriasis and early signs of joint inflammation will receive either guselkumab or standard care. The goal is to see if the drug can stop art…

This study tests a program called Mom♥Health to help mothers of young children reduce their risk of heart disease. About 40 moms with kids aged 5 or younger will receive support and resources through their child's daycare center. The goal is to see if this approach is practical a…

This study tests whether wearing a headset that delivers a flickering 60Hz white light for 30 minutes a day can help ease depression symptoms. Adults with major depressive disorder will use the device at home for three weeks. Researchers will measure how well people stick with th…

This study tests whether a noninvasive brain stimulation technique called tDCS can reduce depression in people with multiple sclerosis. Participants use a headband-like device at home for 30 minutes a day over 30 days, while listening to mindfulness meditation. Half receive real …

This study is testing whether changing the frequency settings on a cochlear implant can improve sound quality and speech understanding for people who use both a cochlear implant and a hearing aid. Thirteen experienced bimodal users will try an experimental frequency setting for o…

This study is testing whether cannabidiol (CBD) tablets can reduce pain and improve daily function in people with knee osteoarthritis. Researchers will compare pain levels between those taking CBD and those not taking it, alongside standard physical therapy. The study aims to enr…

This study tests whether using a special cuff that partly blocks blood flow during light exercise can help people with Achilles injuries get stronger and feel less pain. About 57 adults aged 18 to 65 will be randomly assigned to receive this therapy or standard physical therapy. …

This study is testing whether a standardized 6-week yoga program can reduce pain and disability in 200 adults with chronic back pain. Participants will be randomly assigned to yoga or a control group. The goal is to see if yoga offers a safe, non-drug way to manage this common co…

This study tests whether a safe, mild electrical current applied to the scalp (tDCS) can make speech therapy work better for people who have trouble speaking after a stroke. 24 participants with apraxia of speech will receive both real and sham stimulation at different times to s…

This study offers two proven trauma therapies—Trauma-Focused CBT and Trauma Systems Therapy—to children aged 5-17 with PTSD and their families. Researchers want to see how well these treatments work when children also face stress from racial trauma and adapting to a new culture. …

This study compares two self-management programs (UPLIFT and PACES) against usual care for adults with epilepsy. Researchers will track depression symptoms, quality of life, and seizures over 12 months in 108 participants. The goal is to see if these programs help people manage t…

This study tests whether a special silk dressing (SYLKE®) causes fewer skin problems like rashes, blisters, or redness compared to standard skin glue (Dermabond®) after ACL knee surgery. About 100 people aged 14 to 60 having ACL reconstruction will be randomly assigned to one of …

This study is testing whether changing the low-frequency settings on a cochlear implant can improve hearing for people who are deaf in one ear but have normal hearing in the other. Twenty-two adults will try four different sound maps during their first month after implant activat…

This study tests Jornay PM, a once-daily ADHD pill taken at night, in 30 adults aged 18-60. The goal is to see if it improves focus, emotional control, and daily function from morning through early evening. Researchers will measure symptom changes over 10 weeks.

This study tests a 3-month mobile health cardiac rehab program for people with INOCA (chest pain or ischemia without blocked arteries). Participants use an activity tracker, log exercise, and get weekly coaching. The goal is to see if this approach improves symptoms, daily functi…

This study tests whether adding extra support—like booster sessions and a website—to an 8-week telephone mindfulness program can better reduce stress, anxiety, and depression in people with heart disease or risk factors. Researchers will compare different program options in 160 a…

This study tests whether freezing certain nerves (cryoablation) during total knee replacement surgery can reduce pain and the need for opioid painkillers afterward. About 215 adults scheduled for knee replacement will be randomly assigned to receive either standard surgery or sur…

This study tests whether a smartphone app called SilverCloud, which teaches cognitive behavioral therapy (CBT) skills, can help reduce anxiety and depression in high school students. About 120 teens who screen positive for symptoms will either use the app with a clinician's guida…

This study tests whether a special light therapy called photobiomodulation (PBM) can reduce swelling and tissue hardening caused by radiation treatment in head and neck cancer survivors. Sixty participants who completed radiation at least 3 months ago will be randomly assigned to…

This study tests whether wearing virtual reality goggles during a colonoscopy or upper endoscopy can help patients need less sedation. Ten adults aged 21 to 65 will receive minimal sedation and wear a VR headset during the procedure. Researchers will measure how much sedative is …

This study tests whether a nutritional supplement (complex carbohydrates and essential amino acids) taken for three weeks after hip fracture surgery can reduce muscle loss in adults aged 65 and older. Participants are randomly assigned to receive either the supplement or standard…

This pilot study tests whether a custom splint called a Relative Motion Orthosis (RMO) can help people regain finger motion after an injury that causes stiffness. Sixty-four adults with a stiff middle finger joint will be randomly assigned to receive either standard therapy (stre…

This pilot study tests whether neuromuscular electrical stimulation (NMES) can help people regain strength and function after ankle fracture surgery. About 20 participants will either receive NMES plus standard physical therapy or physical therapy alone. The goal is to see if the…

This study tests whether doing throat exercises before and after neck surgery helps people swallow and speak better. Fifty adults having anterior cervical discectomy and fusion (ACDF) will start exercises one week before surgery and continue for six weeks after, with weekly sessi…

This study tests if a gentle electrical stimulation device, used at home every other day for 8 weeks, can slow vision loss and improve daily function in people with optic neuropathy. Researchers will measure changes in eye structure, visual field, and quality of life in 70 adults…

This study is testing whether an 8-week telephone-based mindfulness program (MIND-BP) can help Black women with high blood pressure lower their blood pressure and reduce stress. The study will compare the mindfulness program to a general support group (BOOST). 300 Black women fro…

This study tests whether adding an extra nerve block (IPACK) to a standard one (adductor canal block) can better control pain and reduce opioid use after knee realignment surgery. About 100 adults undergoing specific knee osteotomies will be randomly assigned to receive either th…

This study tests whether a visual communication tool called MyCareGorithm helps newly diagnosed cancer patients understand their treatment options. About 86 patients with breast or head and neck cancer, along with their caregivers, will use the tool during consultations. The main…

This study compares two 8-week telephone support programs for 120 adults with epilepsy who have mild to moderate depression. One program teaches skills to manage depression, while the other offers group support. Researchers will track mood, quality of life, and seizures for a yea…

This study tests whether cannabidiol (CBD), a compound from cannabis, can reduce PTSD symptoms and improve thinking problems in people with PTSD, including those who also have a mild traumatic brain injury. 120 participants will receive either a low or high dose of CBD or a place…

This study tests whether shining near-infrared light on the forehead can change blood flow in the brains of people with major depression. Researchers will measure brain activity using fMRI and track mood changes with a standard depression questionnaire. The goal is to see if this…

This study tests a 3-week program for older adults (65+) with or without mild dementia and their care partners. Participants get a Fitbit smartwatch, motivational texts, educational videos, and virtual physical therapy sessions. The goal is to see if this tech-based approach is e…

This study tests an 8-week online program called MENTOR that teaches mindfulness, exercise, and nutrition to people who had a traumatic brain injury at least a year ago. Researchers want to see if it improves emotional health, physical activity, and overall well-being. The trial …

Many people with obstructive sleep apnea still feel very sleepy during the day even after using a CPAP machine. This study tests a device called tPBM, which shines red and near-infrared light on the scalp to change brain activity. Researchers will measure brain blood flow and sle…

This study tests whether shining a special light on the forehead (transcranial photobiomodulation) can improve blood flow and thinking in older adults who had a traumatic brain injury 1-2 years ago. Seventy people aged 55-85 will receive either real or sham light therapy for abou…

This pilot study tests whether a device that gently stimulates a nerve in the ear (taVNS) is safe and tolerable for people with chronic kidney disease stages 3-5 who have autonomic nervous system dysfunction. Thirty participants will use the device daily for two weeks. The main g…

This study is testing a new software algorithm called SEDA that reduces background noise for cochlear implant users. Researchers will measure how well 60 participants (ages 12 and older) understand speech in quiet and noisy settings with and without the algorithm. The goal is to …

This small study tests whether empagliflozin (Jardiance), a diabetes medication, can reduce symptoms of major depression. The drug helps the body produce ketones, which may provide an alternative energy source for the brain. Sixteen adults with moderate to severe depression will …

This study tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) combined with talk therapy can reduce anxiety, depression, and existential distress in people with advanced cancer. Two hundred participants will receive either psilocybin or an active…

This study tests whether heart rate data can help guide a non-invasive brain stimulation technique called tDCS for people with mild to moderate depression. One hundred participants will receive either real or sham tDCS at home over 10 sessions. Researchers will monitor heart rate…

This study tests whether a gentle brain stimulation technique (tDCS) combined with standard speech therapy can reduce stuttering severity and its negative impact on daily life. Sixteen adults who stutter will receive both treatments, and researchers will measure changes in speech…

This study tests a remote behavioral program called RELAXaHEAD for people with migraines. About 356 adults will use the app to learn skills that may reduce migraine-related disability and improve quality of life. The goal is to see if this approach works better than usual care, a…

This study tests whether using a pressure cuff that partially blocks blood flow during physical therapy can help people with leg tendon or bone injuries regain strength and muscle mass. About 128 adults aged 18 to 65 with specific leg injuries will be randomly assigned to either …

This study follows adults who have recently received a cochlear implant to track how their ability to distinguish sounds and understand speech changes over time. Participants complete at-home sound tests frequently during the first three months, then return for lab tests up to on…

This study works with over 126,000 adults and clinic staff to improve how primary care clinics identify and accommodate patients with communication disabilities, such as speech or hearing problems. Researchers will test tools to help clinics record these needs in electronic healt…

This study tests a program to help people on long-acting injectable HIV prevention (LAI-PrEP) with social needs like food, housing, and transportation. Researchers will screen participants every 4 months and connect them with community organizations for support. The goal is to se…

This study tests whether a computer algorithm can help doctors give more accurate recommendations for when patients should have their next colonoscopy. Researchers will compare the algorithm's suggestions to traditional methods, looking at both accuracy and the time it takes to m…

This study follows 800 adults with synucleinopathies—diseases like Parkinson's, Lewy body dementia, and multiple system atrophy—to learn how they develop and change over time. Researchers will track symptoms, biological markers, and early signs like dizziness on standing or dream…

This study looks at how social media ads with pictures of unhealthy food, likes, and people of the same race influence how many calories teenagers eat. About 480 teens aged 13-17 who use Instagram daily will take part. Researchers will track what they eat and where they look in t…

This study looks at how the number of 'likes' on social media food ads influences what Black and White teenagers (ages 13-17) choose to buy. Researchers will show ads with many or few likes and featuring Black or White individuals, then ask teens to pick snacks in a hypothetical …

This study tests whether a gentle brain stimulation technique called tDCS, done at home, can improve sleep quality in adults with moderate depression. Researchers will track sleep changes and see if better sleep leads to better mood. The study involves 35 participants and aims to…

This study gives 250 adults in East Flatbush, NYC, a free box of fresh vegetables each week for 20 weeks. Participants choose their veggies from a variety of options. Researchers will measure changes in food security, diet quality, and social connections to see if the program hel…

This study aims to create a North American registry of sudden unexplained death in epilepsy (SUDEP) cases. Researchers will interview family members and review medical records of people with epilepsy who died suddenly. By comparing these cases with living epilepsy patients, they …

This study aims to find the genes responsible for Hirschsprung disease, a condition where nerve cells are missing from parts of the intestine. Researchers will collect DNA samples from 3,000 people with the disease and their close family members. By analyzing common and rare gene…

This study adapts PlayReadVIP, a program that coaches parents on positive interactions during reading and play, for use in family child care homes. Researchers will enroll 240 providers to see if the program improves provider confidence and children's literacy behaviors. The goal…

This study looks at whether doing special swallowing exercises for 12 weeks, with or without a daily protein drink, can strengthen the muscles used for swallowing in older adults who are starting to become frail. The goal is to see if these exercises can improve muscle strength, …

This study tests a program where Black women perinatal nurses guide Black birthing people through pregnancy and postpartum care. The nurses help with medical, social, and emotional needs, and connect patients to resources. Researchers will survey and interview 55 participants to …

This study is testing a new, low-dose food challenge given over several days to diagnose FPIES, a food allergy that causes vomiting and diarrhea. Researchers want to find the safest dose that can still trigger symptoms in people with FPIES. The study involves 72 people aged 1 to …

This study looks at how well a telehealth program called National TeleOncology works for veterans newly diagnosed with lung, colorectal, prostate, or breast cancer. Researchers will track how many veterans use telehealth visits and whether the program affects the quality of care …

This study creates a research registry to track the health of up to 40,000 people exposed to World Trade Center dust after 9/11. Participants include local residents, cleanup workers, and responders. The goal is to better understand respiratory, mental, and general health effects…

This study looks at how taking 81mg of aspirin twice a day affects blood platelets in pregnant women who are at high risk for preeclampsia. Researchers will collect blood samples about 4 weeks after starting aspirin to measure platelet function. The goal is to understand the best…

This study looks at whether people with chronic hepatitis B who have undetectable virus levels in their blood also have undetectable levels in other body fluids like saliva or semen. Researchers will compare treated patients with suppressed virus to untreated patients with active…

This study looks at how the gut and kidneys work together in people with enteric hyperoxaluria, a condition that raises the risk of kidney stones. Researchers will give participants a high-oxalate diet (like spinach) and measure oxalate levels in urine and stool. The goal is to u…

This study looks at how difficult childhood experiences might impact the course of multiple sclerosis (MS). Researchers will work with 300 young adults with relapsing-remitting MS, focusing on Black, Hispanic, and low-income groups often left out of research. Participants will ha…

This study compares two parenting support programs for families with infants up to 6 months old. One group gets standard HealthySteps support, while the other also gets PlayReadVIP, which uses video recordings of parents playing with their child to give personalized feedback. Res…

This study observes 67 adults with lumbar stenosis and low back pain to find out how many have a directional preference—meaning a specific movement (like bending forward or sideways) that eases their pain. Participants will be followed during their usual physical therapy at NYU L…

This study looks at whether treating depression with a common antidepressant (escitalopram) can change brain and blood markers linked to Alzheimer's disease. Researchers will compare the drug to a placebo in 60 adults aged 60 and older who have major depression but no memory prob…

This study looks at whether a computer program called BrainHQ can help adults with traumatic brain injury improve their memory and attention. About 150 people with mild to severe brain injuries will either use BrainHQ or play regular brain games. Researchers will test their think…

This study tests whether a culturally tailored education program helps more people complete colorectal cancer screening. About 50 adults aged 45-75 who are not up-to-date with screening will take part. The program aims to improve screening rates by addressing beliefs and barriers…

This study looks at how virtual reality (VR) food marketing, like ordering from a Wendy's in the Wendyverse, affects snack eating, hunger, and buying intentions in Black and white young adults aged 18-24. Participants will spend about 2 hours in a single visit, experiencing eithe…

This study looks at blood cells called platelets in people who have had a heart attack. Researchers want to understand how these cells work and what genes are involved. They will compare heart attack patients with healthy people and those with stable chest pain. The goal is to le…

This study looks at how exercise affects brain markers linked to anxiety. Thirty adults with anxiety disorders will follow a 4-week virtual exercise program. Researchers will measure specific brain chemicals from blood samples to understand the biological changes behind exercise'…

This study looks at whether educational videos and role-play exercises can help breast cancer patients and their doctors better recognize and manage side effects from certain targeted therapies (antibody drug conjugates). The study involves 30 patients and their clinicians. Resea…

This study enrolls 3,200 adults from immigrant communities in Brooklyn to see if a program offering subsidized, culturally-tailored fresh produce boxes, along with nutrition classes and gardening workshops, can improve fruit and vegetable intake and strengthen social bonds. Parti…

This study examines community-centered safety models (CCSMs) used in U.S. cities to prevent violence among youth and young adults. Researchers will analyze data from 15 cities to see how these alternative crisis response approaches impact homicide and assault rates. The goal is t…

This study looks at why people struggle with self-control, especially when trying to resist tempting foods. Researchers will ask 300 healthy adults to complete tasks that measure how much they would pay to avoid temptation, while also undergoing brain scans and stress tests. The …

This study explores whether seeing TikTok influencers with food makes kids aged 10-13 choose more calories when buying snacks. About 100 participants will watch influencer posts with or without food, then pick snacks in a virtual store. The goal is to understand how social media …

This study looks at whether remote exercise programs (using a smartphone app, live video classes, or in-person sessions) can help people at risk for heart disease become more active. About 30 adults over age 45 who are not currently meeting exercise guidelines will take part. The…

This study aims to improve how children with cochlear implants perceive sound by testing new sound coding strategies. Researchers will compare hearing performance between children and adults, and between those with implants and those with normal hearing. The goal is to understand…

This study looks at whether offering genetic testing for cancer-related genes during regular gynecology visits is practical and acceptable for women aged 25 to 39. Researchers will track how many participants choose to get tested and how many have genetic changes that increase ca…

This study looks at the bacteria living in the lungs of people with a chronic lung condition called bronchiectasis who may also have an NTM infection. Researchers will collect sputum and airway samples from 1000 participants to compare the lung microbiome of those with and withou…

This study aims to understand how the hippocampus, a brain region key for memory and navigation, behaves when people look around and explore. Researchers will record brain activity in 56 adults with epilepsy who already have electrodes implanted for medical reasons. Participants …

This study looks at how the bacteria living in your gut (the microbiome) are linked to health and diseases like cancer and heart disease. Researchers will collect information from 16,000 adults over age 40 through questionnaires and samples. The goal is to build a large database …

This study looks at whether a new quality measurement and coaching strategy can improve treatment for people with opioid use disorder in New York State. Researchers will work with clinic staff to improve how they track and use quality measures. The study involves 35 participants …

This study looks at how mindfulness-based stress reduction (MBSR) affects the brains of 150 adults with generalized anxiety disorder. Participants will be randomly assigned to either an 8-week MBSR program or a stress education class. Researchers will use brain scans and other te…

This study looks at how breathing in dust from the World Trade Center attacks may harm the heart and lungs of FDNY first responders. Researchers will measure certain substances in the blood and breathing tests to find early signs of disease. The goal is to better understand these…

This study looks at the bacteria living in the lungs of smokers with and without early-stage COPD. Researchers will use a bronchoscopy to collect samples and analyze how these bacteria and the body's immune response differ between the two groups. The goal is to better understand …

This study works with the Ramapough Nation to improve food sovereignty and health by promoting traditional farming and nutritious eating. Researchers will collect health surveys, blood and urine samples, and test soil and water for contaminants. The goal is to understand how envi…

This study works with community partners and NYC public hospitals to help people with limited English get better access to language services. The goal is to make sure everyone can use preventive care like screenings and vaccines. Researchers will develop and test new approaches w…

This study tracks 500 people diagnosed with takotsubo (broken heart) syndrome to better understand what causes it and how it affects patients over time. Researchers will monitor heart events, quality of life, and stress levels through medical records and questionnaires. No new tr…

This pilot study is testing whether a device that gently stimulates a nerve in the ear is safe and tolerable for people with chronic kidney disease (CKD). Twenty adults with moderate to advanced CKD will use the device for 15 minutes. Researchers will measure heart rate changes a…

This research study looks at how children and adults who use cochlear implants or auditory brainstem implants hear and understand sounds. Participants will listen to words, sentences, and tones to see how well they identify speech and tell differences in loudness or pitch. The go…

This study looks at how reducing cholesterol levels affects blood cells and blood vessels in people with type 1 diabetes. Researchers will follow 125 participants for one to two months to measure changes in platelet activity, immune cell function, and blood vessel health. The goa…

This study is testing a web-based tool called HELPix Care Plan to help parents of children with medical complexity understand and follow discharge instructions. Researchers will enroll 282 parents to see if the tool reduces errors in comprehension and adherence, and lowers the ch…

This study looks at how stress and anxiety affect learning and decision-making. Researchers will have participants do tasks like putting a hand in ice water or warm water, then measure how they value rewards and predict emotions. The goal is to understand the link between stress,…

This study is testing two ways to help people in New York City get screened for breast, cervical, and colorectal cancer. One group gets educational materials plus help from a trained community health worker, while the other group gets only the materials. The goal is to see which …

This study is looking for ways to predict which people with chronic pancreatitis will get pain relief from a procedure called endoscopic therapy. Researchers will use brain scans, nerve tests, and questionnaires before the procedure, then track pain levels for up to 18 months. Th…

This study looks at how people with cochlear implants understand speech in everyday situations, like conversations with background noise. Researchers will test 460 adults (both with and without hearing loss) using listening tasks that measure effort and comprehension. The goal is…

This study is testing a mobile app called GeriKit to gather more information about older adults (75+) with ischemic heart disease. Researchers want to see if the app helps them better understand patients' health and outcomes, like hospital readmission or quality of life. About 15…

This study looks at 48 adults with advanced lung cancer who are about to start immunotherapy. Researchers will collect samples from the lungs, stool, and blood before and after treatment to see if certain bacteria are linked to better outcomes. The goal is to understand why some …

This study tests a web-based decision aid for people with small kidney tumors (up to 4 cm). The tool provides personalized information about treatment options and their risks and benefits. Researchers will enroll 40 patients to see if the tool improves knowledge, satisfaction, an…

This study uses non-invasive brain stimulation (TMS or tDCS) to explore how the brain creates the intention to move. Researchers will compare healthy volunteers and people with psychogenic movement disorders or non-epileptic seizures. The goal is to better understand these condit…

This study looks at how social media ads affect the food choices and calorie intake of Black and White teenagers aged 13-17. Researchers will show participants different ads and measure how many calories they buy or eat. The goal is to understand if things like ad images or socia…

This study follows people with familial dysautonomia (FD) to learn how the disease changes over time. Researchers will collect routine medical test results and optional blood samples to find biological markers that could help diagnose and treat FD better. The study is observation…

This study follows 1500 adults who had COVID-19 to see how the virus affects their heart and lungs over time. Researchers will track inflammation markers and breathing problems using questionnaires. The goal is to learn more about recovery, not to test a treatment.

This study tests whether a non-invasive device that shines light through the skin can monitor kidney oxygen levels in premature babies born before 30 weeks. The goal is to see if low oxygen levels can predict acute kidney injury early. Researchers will track 100 infants over thei…

This study is recruiting 100 adults with hard-to-treat nontuberculous mycobacterial (NTM) lung infections to see if phage therapy—using viruses that kill bacteria—can help. Researchers will collect blood and airway samples to find biological markers that show whether the treatmen…

This study collects medical records, circumstances, and DNA from children who died suddenly and unexpectedly between ages 11 months and 18 years. Researchers will analyze this information to find risk factors and causes, with the goal of preventing future deaths. Families of affe…

This study looks back at the records of 2000 people who had surgery for a type of pancreatic cyst called IPMN. The goal is to better understand when surgery is needed and how to predict which cysts might turn into cancer. By comparing different patient outcomes, researchers hope …

This study will follow 300 men with early-stage prostate cancer who choose to be treated with high-intensity focused ultrasound (HIFU). Researchers will collect data on side effects, cancer control, and urinary and sexual function over time. The goal is to better understand how w…

This study is creating a database to track what happens to men with localized prostate cancer who choose cryotherapy (freezing the tumor). Researchers will record side effects and how long it takes for PSA levels to rise again. Up to 1,000 men will be followed over time to gather…

This early-phase study is looking at how the drug belzutifan affects a protein called CAIX in people with advanced clear cell kidney cancer. Researchers will use a special PET scan before and after four weeks of belzutifan treatment to measure changes in CAIX levels. The goal is …

This study tests whether a toolkit of strategies—like setting up advisory boards and making materials easier to understand—can improve how patients, families, and researchers work together in pediatric studies. Researchers will compare studies using the toolkit to those using sta…

This study will use data from NYC homeless shelters, Medicaid, and vital records to see if harm reduction programs reduce fatal and non-fatal overdoses. Researchers will also look at whether these programs help people start treatment for substance use disorder and use health serv…

This study looks at whether drinking a protein shake (Ensure Max Protein) for two weeks before and four weeks after joint replacement surgery can improve nutrition levels in patients with osteoarthritis. Researchers will measure blood markers of nutrition at several points. The s…