Freezing away knee pain: new study tests cryoablation after replacement surgery

NCT ID NCT06991231

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether freezing certain nerves (cryoablation) during total knee replacement surgery can reduce pain and the need for opioid painkillers afterward. About 215 adults scheduled for knee replacement will be randomly assigned to receive either standard surgery or surgery plus cryoablation. Researchers will track pain levels, knee function, and opioid use for several months after the procedure.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

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