Lupus drug may be stopped in seniors without flare risk, study tests

NCT ID NCT05799378

First seen Mar 10, 2026 · Last updated Jun 18, 2026 · Updated 16 times

Summary

This study looks at whether people aged 60 and older with stable lupus can safely stop taking hydroxychloroquine, a common medication that can cause eye damage over time. About 330 participants will either continue the drug or switch to a placebo and be monitored for one year. The goal is to see if stopping the drug leads to disease flares, helping doctors balance the risks of eye side effects against lupus symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University Irving Medical Center/New York Presbyterian

    RECRUITING

    New York, New York, 10032, United States

  • Hackensack Meridian Health

    RECRUITING

    Hackensack, New Jersey, 07601, United States

  • Hospital for Special Surgery

    RECRUITING

    New York, New York, 10021, United States

  • Montefiore Medical Center/Albert Einstein College of Medicine

    RECRUITING

    The Bronx, New York, 10461, United States

  • NYC Health + Hospitals/Bellevue

    RECRUITING

    New York, New York, 10016, United States

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

  • Oklahoma Medical Research Foundation

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

  • Penn State MS Hershey Medical Center

    RECRUITING

    Hershey, Pennsylvania, 17033, United States

  • University of California, Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

  • VA NY Harbor Healthcare System

    RECRUITING

    New York, New York, 10010, United States

Conditions

The condition(s) this trial relates to.

systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.