Can genetics and environment explain lupus in the gullah population?
NCT ID NCT00756769
First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time
Summary
This study investigates why African Americans, particularly the Gullah community from the Sea Islands of South Carolina and Georgia, are at higher risk for systemic lupus erythematosus (SLE). By analyzing genetic and environmental factors in 750 participants—including people with lupus, their relatives, and healthy controls—researchers hope to identify specific triggers for the disease. The Gullah population's unique genetic makeup makes them an ideal group for this research.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could uncover specific genetic and environmental triggers for lupus, pointing toward targeted prevention or treatment strategies for high-risk populations.
- What could go wrong
- This is an observational study, not a treatment trial, so it will not directly test any therapy. The findings may not apply to other populations or lead to immediate clinical changes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
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