Probiotics may boost recovery after joint infection surgery

NCT ID NCT06919913

Recruiting now Disease control Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking a daily probiotic capsule (Lactobacillus rhamnosus GG) for six weeks after surgery can improve immune markers and recovery in people treated for a hip or knee joint infection. About 152 adults aged 18–90 will be enrolled. Researchers will measure blood markers of inflammation, patient-reported pain and function, and any complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Lactobacillus rhamnosus GG probiotic (Culturelle)
What this could lead to: If it works, this could point toward a simple, low-cost way to boost recovery and reduce complications after joint infection surgery.
What could go wrong: This is an early-stage study with no phase designation, so results are uncertain. Probiotics may not meaningfully change immune markers or outcomes, and individual responses can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

periprosthetic joint infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTHETIC-JOINT INFECTION

Contacts and locations

Locations

NYU Langone Health
RECRUITING

New York, New York, 10016, United States

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