Can a new eye drop soothe dry eye? a trial puts TRYPTYR to the test

NCT ID NCT07732010

Recruiting now Symptom relief Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This trial investigates whether TRYPTYR, an experimental eye drop, can reduce symptoms and improve eye surface health in adults with dry eye disease. Participants will use the drops twice daily for 30 days. Researchers will measure changes in symptom scores and eye staining patterns to see if the treatment offers relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: an experimental eye drop called TRYPTYR (acoltremon ophthalmic solution 0.003%)
What this could lead to: If it works, this could offer a new treatment option for people with dry eye disease, potentially reducing discomfort and improving quality of life.
What could go wrong: This is a small, early-phase trial with only 50 participants, so results may not apply to everyone. The treatment may not prove more effective than existing options, and side effects are possible.

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Conditions

The condition(s) this trial relates to.

dry eye syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRY EYE DISEASE (DED)

Contacts and locations

Locations

NYU Langone Health
RECRUITING

New York, New York, 10016, United States

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Other studies related to the condition(s) this trial covers.