New combo therapy aims to tame melanoma treatment side effects
NCT ID NCT05428007
First seen Jan 11, 2026 · Last updated Jun 14, 2026 · Updated 25 times
Summary
This study tests whether adding the drug sarilumab to a standard immunotherapy combination can reduce severe side effects and work better for people with advanced melanoma that cannot be removed by surgery. About 105 participants will receive sarilumab along with ipilimumab, nivolumab, and relatlimab. The goal is to see if this approach is safer and more effective than current treatments.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
Contact Phone: •••-•••-••••
Contact
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The Angeles Clinic at Cedars Sinai
RECRUITINGLos Angeles, California, 90025, United States
Contact
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.