Can your genes predict your melanoma risk?
NCT ID NCT00591500
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This study investigates why some people are more susceptible to melanoma, a type of skin cancer. Researchers will compare the genes and sun exposure histories of people who have had multiple melanomas, those with a single melanoma, and similar people without melanoma. By analyzing DNA from cheek swabs and blood, they hope to identify genetic variations that affect how the skin repairs sun damage and responds to the sun. The goal is to understand how genes and sun habits interact to influence melanoma risk.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Questionnaire and DNA analysis (buccal swabs and blood)
- What this could lead to
- If successful, this could identify genetic markers that predict higher melanoma risk, potentially leading to personalized prevention strategies.
- What could go wrong
- This is an observational study, so it cannot prove cause and effect. Results may not apply to all populations, and genetic findings may not translate into immediate clinical use.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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