UNRESECTABLE MELANOMA
Clinical trials for UNRESECTABLE MELANOMA explained in plain language.
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Fighting skin cancer with a Patient's own supercharged immune cells
Disease control Recruiting nowThis study is testing a personalized cell therapy called lifileucel for people with advanced melanoma that has worsened after standard immunotherapy. Doctors take immune cells from a patient's tumor, grow large numbers of them in a lab, and infuse them back into the patient to at…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE2 • Sponsor: Iovance Biotherapeutics, Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Four-Drug attack on advanced skin cancer aims to boost effectiveness, reduce side effects
Disease control Recruiting nowThis study is testing whether adding a drug called sarilumab to a combination of three other immunotherapy drugs works better for people with advanced melanoma that cannot be removed by surgery. The main goals are to see if this four-drug combination is safe, tolerable, and more …
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE2 • Sponsor: NYU Langone Health • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Dual attack: fighting cancer while protecting a transplanted kidney
Disease control Recruiting nowThis study is testing a new treatment approach for people who have had a kidney transplant and now have advanced skin cancer that cannot be removed by surgery or has spread. The goal is to see if a combination of cancer immunotherapy drugs (nivolumab and ipilimumab) can be given …
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New drug duo aims to outsmart tough cancers that resist standard treatment
Disease control Recruiting nowThis study is testing whether combining two drugs, cabozantinib and nivolumab, can help control advanced melanoma or head and neck cancer that has worsened despite standard immunotherapy. It will enroll about 150 adults whose cancer has progressed on prior treatment. A key goal i…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New Two-Pronged attack on Tough-to-Treat skin cancer
Disease control Recruiting nowThis study is testing a new, modified drug called IOV-3001 in combination with a personalized cell therapy (lifileucel) for people with advanced melanoma that has spread or cannot be removed by surgery. The main goals are to find a safe dose and see how well the body handles the …
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE1, PHASE2 • Sponsor: Iovance Biotherapeutics, Inc. • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Custom-Made vaccine aims to train immune system to fight advanced cancers
Disease control Recruiting nowThis study is testing a new, personalized vaccine designed to target the unique proteins on a patient's own cancer cells. It is being given alongside an existing immunotherapy drug (pembrolizumab) to see if the combination is safe and can help control advanced solid tumors that h…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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New hope for Tough-to-Treat skin cancer
Disease control Recruiting nowThis study is testing a new oral drug, LNS8801, for people with advanced melanoma that has spread and no longer responds to standard immunotherapies. Researchers want to see if LNS8801, taken alone or combined with the drug pembrolizumab, can stop or slow cancer growth better tha…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE2, PHASE3 • Sponsor: Linnaeus Therapeutics, Inc. • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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Could your diet help beat cancer? new trial tests Food's power to boost melanoma treatment
Disease control Recruiting nowThis study is testing whether adding specific prebiotic foods to the diet can improve gut health and help people with advanced melanoma respond better to their first-line immunotherapy treatment. Researchers will enroll 75 patients starting immunotherapy and provide them with a s…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 13, 2026 15:06 UTC
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Can a simple blood test and scan predict your Cancer's future?
Knowledge-focused Recruiting nowThis study aims to learn if a special scan (PET/CT) and a blood test for tumor DNA can help doctors predict, very early on, which patients with advanced melanoma will respond well to immunotherapy and which might experience side effects. It will enroll 24 patients who are startin…
Matched conditions: UNRESECTABLE MELANOMA
Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Mar 17, 2026 12:55 UTC