Second chance: melanoma patients get access to slightly Off-Spec cell therapy

NCT ID NCT05398640

AVAILABLE Disease control Sponsor: Iovance Biotherapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Apr 23, 2026 · Last updated May 15, 2026 · Updated 6 times

Summary

This program offers a special cell therapy called AMTAGVI to people with advanced melanoma that cannot be removed by surgery or has spread. The treatment is made from the patient's own immune cells and is normally only given when it meets strict quality standards. Here, patients can receive batches that are slightly out of specification but still considered safe and helpful after a careful risk-benefit review.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Avera Cancer Institute
AVAILABLE

Sioux Falls, South Dakota, 57105, United States
Banner Health MD Anderson
AVAILABLE

Gilbert, Arizona, 85234, United States
Barbara Ann Karmanos Cancer Hospital
AVAILABLE

Detroit, Michigan, 48201, United States
City of Hope
AVAILABLE

Duarte, California, 91010, United States
Cleveland Clinic
AVAILABLE

Cleveland, Ohio, 44195, United States
Dana Farber Cancer Institute
AVAILABLE

Boston, Massachusetts, 02215, United States
Emory University Hospital
AVAILABLE

Atlanta, Georgia, 30322, United States
Fox Chase Cancer Center
AVAILABLE

Philadelphia, Pennsylvania, 19111, United States
Fred Hutchinson Cancer Research Center
AVAILABLE

Seattle, Washington, 98109, United States
Georgetown University Medical Center
AVAILABLE

Washington D.C., District of Columbia, 20007, United States
Hackensack University Medical Center
AVAILABLE

Hackensack, New Jersey, 07601, United States
HonorHealth
AVAILABLE

Scottsdale, Arizona, 85258, United States
Intermountain Healthcare
AVAILABLE

Salt Lake City, Utah, 84107, United States
Lehigh Valley Health Network
AVAILABLE

Allentown, Pennsylvania, 18105, United States
MD Anderson Cancer Center - U of Texas
AVAILABLE

Houston, Texas, 77030, United States
MD Anderson Cancer Center at Cooper
AVAILABLE

Camden, New Jersey, 08103, United States
Massachusetts General Hospital
AVAILABLE

Boston, Massachusetts, 02114, United States
Medical College of Wisconsin
AVAILABLE

Milwaukee, Wisconsin, 53226, United States
Memorial Sloan Kettering Cancer Center
AVAILABLE

New York, New York, 10065, United States
Moffitt Cancer Center
AVAILABLE

Tampa, Florida, 33612, United States
New York Presbyterian Weill Cornell Medical Center
AVAILABLE

New York, New York, 10065, United States
Northside Hospital
AVAILABLE

Atlanta, Georgia, 30342, United States
Northwestern University
AVAILABLE

Chicago, Illinois, 60611, United States
Oregon Health and Science University
AVAILABLE

Portland, Oregon, 97239, United States
Orlando Health Cancer Institute
AVAILABLE

Orlando, Florida, 32806, United States
Providence Cancer Center Oncology and Hematology Care Clinic
AVAILABLE

Portland, Oregon, 97213, United States
SCRI Oncology Partners
AVAILABLE

Nashville, Tennessee, 37203, United States
South Austin Medical Center
AVAILABLE

Austin, Texas, 78704, United States
St. Lukes Hospital
AVAILABLE

Bethlehem, Pennsylvania, 18015-1000, United States
Stanford Hospital
AVAILABLE

Stanford, California, 94305, United States
Texas Oncology-Baylor Charles A. Sammons Cancer Center
AVAILABLE

Dallas, Texas, 75246, United States
The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
AVAILABLE

Baltimore, Maryland, 21287-0013, United States

Contact
The University of Kansas Cancer Center
AVAILABLE

Westwood, Kansas, 66205, United States
Thomas Jefferson University
AVAILABLE

Philadelphia, Pennsylvania, 19701, United States
University of Chicago
AVAILABLE

Chicago, Illinois, 60637, United States
University of Colorado Hospital
AVAILABLE

Aurora, Colorado, 80045, United States
University of Iowa Hospital
AVAILABLE

Iowa City, Iowa, 52242, United States
University of Kentucky-Markey Cancer Center
AVAILABLE

Lexington, Kentucky, 40536, United States
University of Louisville - James Graham Brown Cancer Center
AVAILABLE

Louisville, Kentucky, 40202, United States
University of Maryland
AVAILABLE

Baltimore, Maryland, 21201, United States
University of Miami
AVAILABLE

Miami, Florida, 33136, United States
University of Nebraska Medical Center
AVAILABLE

Omaha, Nebraska, 68198, United States
University of Pittsburgh Medical Center - Hillman Cancer Center
AVAILABLE

Pittsburgh, Pennsylvania, 15232, United States
VCU Medical Center (Virginia Commonwealth University)
AVAILABLE

Richmond, Virginia, 23298, United States
Vanderbilt University
AVAILABLE

Nashville, Tennessee, 37232, United States
Washington University - Barnes Jewish Hospital
AVAILABLE

St Louis, Missouri, 63110, United States
West Penn Hospital
AVAILABLE

Pittsburgh, Pennsylvania, 15224, United States
Yale New Haven Hospital
AVAILABLE

New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

METASTATIC MELANOMA UNRESECTABLE MELANOMA