Iovance Biotherapeutics, Inc.

This program offers a special cell therapy called AMTAGVI to people with advanced melanoma that cannot be removed by surgery or has spread. The treatment is made from the patient's own immune cells and is normally only given when it meets strict quality standards. Here, patients …

This study tests a treatment called lifileucel, made from a patient's own immune cells (tumor-infiltrating lymphocytes), for advanced endometrial cancer that has been treated before. About 60 participants will receive this cell therapy to see if it can shrink tumors. The goal is …

This study tests a treatment made from your own immune cells (called TILs or LN-145) for advanced lung cancer that has spread. About 170 people with a specific type of lung cancer will receive their own expanded immune cells to see if tumors shrink. The goal is to measure how man…

This study tests whether combining a personalized cell therapy (lifileucel) with an immunotherapy drug (pembrolizumab) works better than the drug alone for people with advanced melanoma that cannot be removed by surgery or has spread. About 670 adults with untreated melanoma will…

This early-stage trial tests a new drug (IOV-3001) combined with an immune cell therapy (lifileucel) in adults with advanced melanoma that has stopped responding to standard treatments. The goal is to find a safe dose and see if the combination can help control the disease. About…