UNRESECTABLE MELANOMA
Clinical trials for UNRESECTABLE MELANOMA explained in plain language.
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Could an old malaria drug help beat melanoma?
Disease control TerminatedThis study tested whether adding hydroxychloroquine (a drug used for malaria) to standard targeted therapy (dabrafenib and trametinib) could help control advanced melanoma that has a specific gene change (BRAF V600E/K) and high LDH levels. The trial was stopped early after enroll…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 17, 2026 06:50 UTC
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New combo for tough melanoma shows promise but trial halted early
Disease control TerminatedThis study tested a combination of two drugs (duvelisib and nivolumab) in 13 people with advanced melanoma that had stopped responding to standard immunotherapy. The goal was to find the best dose and see if the combination could shrink tumors or slow the disease. The trial was t…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE1, PHASE2 • Sponsor: John Kirkwood • Aim: Disease control
Last updated May 17, 2026 06:46 UTC
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Engineered virus takes on deadly skin cancer in early trial
Disease control TerminatedThis early-phase trial tested a specially modified virus (VSV-IFNbetaTYRP1) in 12 people with advanced melanoma that had spread or could not be removed. The virus was injected directly into tumors and into a vein to see if it could safely trigger the immune system to attack cance…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Melanoma combo therapy trial halted early after 20 patients
Disease control TerminatedThis study tested whether adding an experimental drug (CMP-001) injected directly into tumors to the standard immunotherapy nivolumab works better than nivolumab alone for people with advanced melanoma that cannot be removed by surgery or has spread. The trial was stopped early a…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE2, PHASE3 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated May 05, 2026 11:55 UTC