UNRESECTABLE MELANOMA
Clinical trials for UNRESECTABLE MELANOMA explained in plain language.
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New combo shows promise against tough skin cancer
Disease control CompletedThis study tested whether adding bevacizumab to ipilimumab helps people with advanced melanoma that cannot be removed by surgery. 169 participants received either ipilimumab alone or with bevacizumab. The goal was to see if the combination improved overall survival and slowed can…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 05:32 UTC
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Immune cell therapy shows promise for Hard-to-Treat melanoma
Disease control CompletedThis early-phase study tested a new treatment called TBio-4101 for people with advanced melanoma that did not respond to standard therapies. The treatment uses a patient's own immune cells (TILs) that are grown in a lab and given back after chemotherapy and a drug called IL-2. Th…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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Experimental combo shows promise for Tough-to-Treat melanoma
Disease control CompletedThis study tested a new cancer vaccine (BNT111) combined with an immunotherapy drug (cemiplimab) in 184 people with advanced melanoma that had stopped responding to prior treatment. The goal was to see if the combination could shrink tumors better than either treatment alone. Par…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE2 • Sponsor: BioNTech SE • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Gentler chemo before cell therapy shows promise for tough melanoma
Disease control CompletedThis study tested a lower dose of chemotherapy given before infusing a patient's own tumor-fighting immune cells (lifileucel) for melanoma that has spread or can't be removed. Eleven adults with advanced melanoma took part. The goal was to see if the milder chemo prep still allow…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE2 • Sponsor: University of Kansas Medical Center • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New combo therapy shows promise for Tough-to-Treat melanoma
Disease control CompletedThis early-phase study tested a combination of two drugs, trametinib and ceritinib, in 27 people with advanced melanoma that had stopped responding to standard treatments. The main goals were to find the safest dose and see if the combination could shrink tumors. The study is com…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 14, 2026 12:03 UTC