Lighter chemo before TIL therapy shows promise for tough melanoma

NCT ID NCT06151847

First seen May 01, 2026 · Last updated Jun 16, 2026 · Updated 9 times

Summary

This study tested whether using a lower dose of chemotherapy before giving back a patient's own tumor-fighting immune cells (lifileucel) is safe and effective for advanced melanoma that can't be removed by surgery or has spread. Eleven adults with stage IV or unresectable melanoma took part. The goal was to see if the reduced chemo still allows the immune cells to work while causing fewer side effects.

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Contacts and locations

Locations

  • University of Kansas Cancer Center

    Kansas City, Kansas, 66160, United States

Conditions

Explore the condition pages connected to this study.