University Of Kansas Medical Center

This study is testing a non-surgical treatment for women aged 65 and older with early-stage breast cancer. Instead of surgery, participants receive five precise, high-dose radiation treatments to the tumor. Researchers will track side effects and quality of life to see if this ap…

This study is testing a family support program designed to help children with acute lymphoblastic leukemia (ALL) maintain a healthy weight during early treatment. Families participate in six counseling sessions focused on nutrition, activity, and stress management. The researcher…

This small pilot study is testing whether taking whey protein supplements can help older adults who are starting to show signs of frailty. Researchers want to see if the protein improves brain antioxidant levels, measured by MRI scans, and also helps with strength, balance, and t…

This study aims to personalize treatment for triple-negative breast cancer before surgery. It will test if the number of immune cells in a patient's tumor and how well the tumor shrinks on MRI scans can help doctors decide the best type and amount of chemo-immunotherapy. The goal…

This study is testing if a spray-on drug called tranexamic acid works as well as the standard spray (thrombin) to control bleeding under skin grafts for burn wounds. The goal is to see if the new option is just as effective at preventing blood clots under the graft and helping it…

This study is testing whether switching to a newer type of e-cigarette can help adult cigarette smokers reduce their exposure to harmful chemicals. It will enroll 500 smokers who want to try e-cigarettes. Some participants will also receive a quit-smoking medication (varenicline)…

This study is testing a program to help low-income pregnant women quit smoking. It combines daily text message support with small financial rewards for staying smoke-free. Researchers want to see if this approach is practical and well-liked by participants, and if it helps them q…

This study is testing whether adding hands-on cooking classes to a standard weight loss program helps young adults with intellectual disabilities lose more weight and keep it off. Over two years, researchers will compare weight loss, health markers, and daily living skills betwee…

This study is testing a new medical device called ClearPetra™, which uses suction to remove kidney stones during surgery. Researchers want to see if it helps clear stones more completely and reduces infections after surgery compared to the standard tools. The trial will involve 1…

This early-stage study is testing a new cell therapy for adults with certain blood cancers who have received a bone marrow transplant from a partially matched family donor. Researchers take a special type of the patient's own immune cells, grow and activate them in a lab, and the…

This study is testing how cancer doctors can help endometrial cancer survivors who have obesity start weight management programs. Researchers want to see if connecting survivors with a specialized weight clinic helps them begin weight loss medications and improve their health. Th…

This study compares two common anesthesia methods used during emergency stroke surgery to remove blood clots. Researchers want to see whether inhaled anesthesia or intravenous (IV) anesthesia leads to better recovery and independence 90 days after surgery. The study will help doc…

This study is comparing two different dosing schedules for common cancer immunotherapies (pembrolizumab and nivolumab) to see if one causes fewer severe side effects. Researchers want to know if giving higher doses less frequently causes more problems than giving lower doses more…

This early-stage trial is testing a new way to deliver radiation to liver tumors that cannot be surgically removed. The goal is to find the highest dose of this targeted radiation that is safe for patients. After the radiation, participants will receive a standard immunotherapy d…

This study is testing whether a nutritional supplement called HMB can help female athletes maintain leg muscle mass and strength while recovering from ACL knee surgery. About 30 women will be randomly assigned to receive either the HMB supplement or a placebo during their rehabil…

This study is testing two approaches to help rural children with obesity: a mobile health program for families and training for clinics. Researchers want to see if these methods help children lose weight and improve their eating and activity habits. The study involves over 1,000 …

This study is testing if taking the quit-smoking medication bupropion for 6 months works better than the usual 7-week course for African American daily smokers. It will enroll 500 adults who want to quit and provide them all with personalized counseling. The main goal is to see i…

This study is testing whether adding an oral drug called pirfenidone to an existing immunotherapy (atezolizumab) can help control advanced non-small cell lung cancer that has come back or spread after initial treatments. It will involve about 25 adults to first check safety and t…

This study is testing whether adding yoga to a standard diet and exercise program helps people with overweight or obesity lose more weight. Researchers will compare a program with aerobic exercise plus yoga to one with just aerobic exercise. They will also check if the yoga group…

This study tests whether training pediatricians to coach parents on talking more with their babies during regular check-ups can improve children's language development. It involves 400 families with infants up to age 2, comparing clinics that provide this coaching to those that g…

This study is testing whether a mobile app for parents can help their 3-4 year old children follow healthy daily movement guidelines. Researchers will compare 80 families using the app to a group that gets it later. The app provides weekly tips and goals to encourage more physica…

This study aims to find the best way to deliver a proven diabetes prevention program to adults with prediabetes in rural Kansas. It will compare a group video class with a self-guided program, and test different ways to recruit participants. The goal is to help people lose weight…

This study is testing a new way to help more people get screened for colorectal cancer in their regular doctor's offices. Researchers are working with 20 primary care clinics across the US to see if a special planning tool and team-based approach can increase screening rates. The…

This study is testing whether a weight loss program can help prevent or delay Alzheimer's disease in adults with Down syndrome. 81 adults with Down syndrome who are overweight but do not have dementia will be assigned to either a weight loss group or a general health education gr…

This study aims to measure how much a minimally invasive procedure reduces pain in women with pelvic congestion syndrome, a common cause of chronic pelvic pain. Researchers will perform a vein-blocking procedure using tiny coils and then track participants' pain levels using a su…

This study is testing two different ways to deliver a proven talk therapy for insomnia to people with multiple sclerosis (MS). Researchers want to see if one-on-one video sessions with a therapist work better than a self-guided online program at improving sleep, reducing fatigue,…

This study is testing a text message support program called CuidaTEXT for Latino caregivers of family members with Alzheimer's or related dementias. Researchers want to see if receiving daily tips, education, and encouragement via text can help reduce caregivers' feelings of depr…

This study is testing a different type of needle used in a common back pain procedure called radiofrequency ablation. Researchers want to see if this new needle provides better pain relief compared to standard pain management techniques like medications and physical therapy. The …

This study aims to understand how day-to-day changes in stress levels affect a person's ability to lose weight, be active, and sleep well during a standard weight loss program. Researchers will follow 50 adults with obesity who are already enrolled in a community weight loss prog…

This study is creating a collection of blood, urine, and tissue samples from people with bladder cancer. Researchers will use this 'biorepository' to study how bladder cancer develops, returns after treatment, and affects survival over time. The study involves 1,000 participants …

This study is creating a large collection of health information and biological samples from people with various scarring lung diseases. Researchers will use this 'biobank' to look for patterns, risk factors, and potential targets for future treatments. The goal is to better under…

This study aims to learn more about the benefits of a device called RetroPerc®, which surgeons already use to help reach the kidney during a common stone removal surgery (PCNL). Researchers will observe 150 adults who are already scheduled for this surgery as part of their regula…

This study aims to understand how a specific form of muscular dystrophy (FSHD) progresses in children and teenagers. Researchers will follow 80 participants for two years, using movement tests and full-body MRI scans to track changes in muscle health and function. The goal is to …

This study aims to understand how bladder cancer treatment affects the body's energy use and muscle function. Researchers will measure these changes in 30 patients undergoing chemotherapy and surgery. The goal is to gather information that could help design better supportive care…

This study aims to understand how GLP-1RA weight loss medications affect muscle mass and bone strength in women aged 35-60. Researchers will track 50 women newly prescribed these drugs to see if their natural estrogen levels influence these changes. The goal is to gather knowledg…

This study is creating a registry to collect information from 1,500 people with triple negative breast cancer or inherited genetic mutations. Researchers want to understand how specific genetic changes affect cancer treatment responses and long-term survival. The registry will tr…

This study is testing whether feeding critically ill patients for only 12 hours per day is as safe and practical as the standard 24-hour feeding. Researchers will compare both schedules in 20 ICU patients to see how they affect blood sugar control, sleep, and feeding tolerance. T…