Gut bacteria booster may stop transplant complication

NCT ID NCT04373057

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a dietary supplement called galacto-oligosaccharide (GOS) can prevent acute graft-versus-host disease (GVHD) in people receiving a stem cell transplant. GVHD is a serious complication where donor cells attack the patient's body. The supplement aims to change gut bacteria to reduce this risk. The trial involves 128 adults aged 18-80 and has two phases: first finding the best dose, then comparing GOS to a placebo.

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Conditions

The condition(s) this trial relates to.

acute graft versus host disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Duke

    ACTIVE_NOT_RECRUITING

    Durham, North Carolina, 27710, United States

  • Kansas University Medical Center

    RECRUITING

    Kansas City, Kansas, 66160, United States

    Contact