University Of Kansas Medical Center

This study tested whether text message reminders and rewards could help people who smoke to stick with their quitline counseling and take their medication. Twenty adults who smoked daily took part. They received a prescription for a stop-smoking drug and were referred to a quitli…

This pilot study tested a new, shorter radiation schedule (ultra-hypofractionation) in 13 men with early-stage prostate cancer. The goal was to see if this approach causes fewer urinary side effects while still controlling the cancer. Participants had low- to intermediate-risk pr…

This small study tested whether losartan, a blood pressure medicine, can help clear mucus from the lungs of people with cystic fibrosis who cannot take newer CFTR therapies. Thirteen adults with mild to moderate lung disease took losartan for over 12 weeks. Researchers measured c…

This phase 2 trial tested whether a reduced dose of chemotherapy drugs (fludarabine and cyclophosphamide) given before infusing a patient's own tumor-fighting immune cells (lifileucel) could work for advanced melanoma that has spread or can't be removed. Eleven adults with stage …

This pilot study tested a web-based version of the DECIDE program, called eDECIDE, which teaches problem-solving skills to help African Americans manage type 2 diabetes. The study involved 36 participants and compared the online program to the traditional in-person group sessions…

This early-stage study tested whether stem cells from donated umbilical cords are safe for people with a serious condition called acute graft versus host disease (aGVHD), which can happen after a bone marrow transplant. Twenty-four adults received one of two doses of these stem c…

This study tested whether two types of intermittent fasting—eating very little a few days a week or eating only during an 8-hour window—can help people with type 2 diabetes improve their blood sugar control. Fifty-seven adults with diabetes followed one of these diet plans for a …

This study looked at whether giving doctors the results of a blood test called ELF helps them better diagnose advanced liver scarring (fibrosis) in people with fatty liver disease. About 450 patients were randomly assigned to have the ELF test or not during their liver clinic vis…

This study tested whether MRI can detect and monitor interstitial lung disease (lung scarring) in people with scleroderma. Twenty-five adults with scleroderma underwent both MRI and CT scans. A subset also breathed in a special xenon gas to see how well their lungs exchange oxyge…

This study tested a 4-week sleep health program in 30 adults aged 45-64 to see if it could improve sleep and potentially delay Alzheimer's disease. Participants learned strategies to enhance their sleep health. The study measured how acceptable and effective the program was, usin…

This study tested a program called eMOMS that combines breastfeeding support with a diabetes prevention plan for pregnant women who were overweight or obese before pregnancy. The program was delivered by a health coach through a mobile app. Researchers wanted to see if it could h…

This study tested a swimming and water safety program designed for children with autism spectrum disorder. The program uses individualized teaching methods and sensory modifications to help kids learn to swim and stay safe around water. Over 350 children with autism took part, an…

This study looked at whether doing kangaroo care (skin-to-skin contact) right in the operating room after a C-section helps mothers feel more satisfied and have less pain. 158 mothers with a single, full-term baby took part. Researchers measured satisfaction, pain levels, and bab…

This study tested an online training program called CHATO for nursing home staff who care for people with Alzheimer's or other dementias. The training aimed to improve how staff communicate, which may reduce behavioral symptoms like agitation or rejection of care. Over 5,000 staf…

This study compared two FDA-approved lasers used to break up kidney stones during surgery: the newer SOLTIVE Thulium Fiber Laser and the standard Ho:YAG laser. About 100 adults with a single stone smaller than 2 cm took part. Researchers measured how well each laser cleared stone…

This study tested whether singing and vocal exercises could improve lung function in people with chronic obstructive pulmonary disease (COPD). Five adults with COPD took part in virtual singing sessions twice a week for four weeks, guided by a music therapist. Researchers measure…

This study tested whether a long-acting numbing drug called liposomal bupivacaine (Exparel) can reduce pain and opioid use after skin graft harvesting in burn patients. 74 adults with small burns received either Exparel, lidocaine, or a nerve block. Researchers measured pain scor…

This study tested whether a six-week sleep therapy program (CBT-I) could improve thinking and memory in older adults aged 60-85 with insomnia. Two hundred participants were randomly assigned to either CBT-I or a sleep education program. A small group also had brain scans to see i…

This study tested whether a 12-week online dance program is practical and enjoyable for young adults with Down Syndrome. Twenty participants joined two 35-minute group dance sessions each week. Researchers measured attendance, safety, and changes in fitness and thinking skills. T…

This study tested whether having a doula—a trained support person—before, during, and after delivery improves how Black birthing people feel about their care. 30 participants completed surveys about communication with their provider and overall care. The goal was to see if doula …

This study tested whether stem cells taken from a person's own fat tissue are safe to inject into weakened muscles. Nine people with inclusion body myositis received injections in their forearm and thigh. The main goal was to check for side effects, not to measure improvement, th…

This study looked at whether two specific diets—the ketogenic diet and the Therapeutic Lifestyles Changes diet—could improve thinking and memory in people with Alzheimer's disease. Researchers measured changes in cognitive test scores over three months in 84 adults aged 50 to 90 …

This study tested whether a specialized swim program (Sensory Enhanced Aquatics) helps autistic children aged 5-9 learn swimming and water safety better than standard lessons. Fifty-one children participated in 16 half-hour lessons. Researchers measured swimming skills before and…

This pilot study tested whether a weight loss program before total knee replacement helps improve recovery. 24 adults with obesity (BMI 35-40) were assigned to either a very low-calorie diet with health coaching or standard care. The goal was to see if the program was feasible an…

This study tested whether a long-acting painkiller called Exparel (liposomal bupivacaine) can control pain better after open or laparoscopic hernia repair. Nineteen adults having hernia surgery received Exparel along with standard care. Researchers measured patient satisfaction w…

This study tested whether a 12-session program combining yoga and support groups could reduce stress for caregivers of young adults with intellectual and developmental disabilities. Twenty caregivers participated, and researchers measured stress levels, cortisol, and how many ses…

This study tested whether a drug called megestrol (an appetite stimulant) could help children aged 9 months to 9 years who rely on feeding tubes transition to eating by mouth. About 70 kids received either megestrol or a placebo, along with a 24-week behavioral feeding program. T…

This completed study reviewed medical charts of 45 women whose copper IUDs broke during removal, requiring a hysteroscopy (a camera-guided procedure) to take out the pieces. Researchers looked for patient-related factors that might raise the risk of IUD fragmentation. The goal is…

This study looked at how different types of exercise affect thinking skills and brain health in healthy older adults aged 65 to 80. Researchers measured changes in memory, attention, and other mental abilities, as well as brain volume, over 12 months. The goal was to learn more a…

This study tested whether tirzepatide, a weight-loss drug, could change certain markers in the blood, breast tissue, and mammograms that are linked to breast cancer risk. It included 25 women with obesity and other breast cancer risk factors. The goal was to see if the drug might…

This study tested a device that measures how much pressure physical therapists apply during spinal mobilization for low back pain. Researchers enrolled 50 healthy adults and people with chronic low back pain to see if the tool could reliably track joint motion, force, and tissue …

This study tested whether a pop-up alert in the electronic medical record could help doctors remember to refer patients with fatty liver disease (NASH) to a liver specialist. Thirty doctors from internal medicine, family medicine, and endocrinology took part. The goal was to see …

This study tested a special MRI that uses inhaled xenon gas to take detailed pictures of lung function in people with pulmonary arterial hypertension (PAH). Ten adults with PAH had four scans over 18 weeks to see how their lungs processed the gas. The goal was to find new ways to…

This completed study looked at lung function in 42 people recovering from COVID-19. Participants inhaled a special form of xenon gas that shows up on MRI scans, allowing researchers to see how well different parts of the lungs were working. The goal was to understand how mild, mo…

This study tested a program called Alianza Latina to improve dementia care for older Latinos. Researchers trained primary care doctors to better detect and treat dementia, and provided bilingual health navigators to help patients and their caregivers. The study involved 243 parti…

This study looked at 158 adults to find out if certain traits or risk factors can predict who will develop chronic pain after lower back surgery. Researchers measured pain severity, disability, and other health factors using questionnaires. The goal was to better understand why s…

This study tested a program called KanSurvive, which uses virtual education sessions and practice support to help rural primary care clinics improve follow-up care for cancer survivors. Researchers worked with 15 rural practices to see if they could better follow guidelines for m…

This study looked at how different types of exercise (interval vs. continuous) and intensity levels (moderate vs. high) affect aerobic fitness and blood vessel health in people who have had a stroke. 59 participants used a seated stepper that moves both arms and legs. The goal wa…

This study used brain scans (fMRI) to see what happens in the brain when heavy drinkers decide whether to drink alcohol, especially when they have important plans the next day. 52 heavy drinkers took part. The goal was to understand how the brain weighs the choice to drink agains…

This study tested whether a brain-healthy version of soul food, called the MIND+SOUL diet, is practical and well-liked by older African Americans at risk for heart disease and cognitive decline. Twenty-nine participants aged 55 and older took cooking classes and received dietary …

This study tested whether different nicotine concentrations in e-cigarettes (5% vs 1.8%) change how much smokers puff, how much nicotine they get, and whether they switch completely from cigarettes. Fifty-two Black and white smokers who wanted to switch to e-cigarettes for 6 week…