Weight loss before knee surgery shows promise in small trial
NCT ID NCT05853497
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This pilot study tested whether a weight loss program before total knee replacement helps improve recovery. 24 adults with obesity (BMI 35-40) were assigned to either a very low-calorie diet with health coaching or standard care. The goal was to see if the program was feasible and could reduce pain and improve knee function after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Multi-Component Weight Loss Intervention (behavioral: very low-calorie diet, health coaching, physical activity)
What this could lead to
If it works, this could point toward a standard weight loss program before knee replacement to improve outcomes like pain and function.
What could go wrong
This is a very small pilot study (24 people) testing feasibility, not effectiveness. Results may not apply to everyone, and the strict diet may be hard to follow.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Kansas Medical Center
Kansas City, Kansas, 66160, United States