Can Weight-Loss surgery change how medications work?
NCT ID NCT03519906
First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This study investigates whether bariatric surgery, such as gastric bypass or sleeve gastrectomy, changes how the body absorbs the common blood-pressure medication metoprolol. Researchers will measure drug levels in the blood of 12 patients before and after surgery. The goal is to understand if surgery alters medication effectiveness, which could guide future dosing recommendations.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- metoprolol
- What this could lead to
- If successful, this could help doctors adjust medication doses for patients after bariatric surgery, ensuring treatments remain effective.
- What could go wrong
- This is a small, early-stage study with only 12 participants, so results may not apply to everyone. Individual variations in surgery and metabolism could limit the findings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
St. Olavs University Hospital
RECRUITINGTrondheim, Norway
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- Can Weight-Loss surgery change how medications work?