New MRI method could spot lung damage without radiation

NCT ID NCT05204355

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether MRI can detect and monitor interstitial lung disease (lung scarring) in people with scleroderma. Twenty-five adults with scleroderma underwent both MRI and CT scans. A subset also breathed in a special xenon gas to see how well their lungs exchange oxygen. The goal was to see if MRI could replace CT scans, which use radiation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
MRI and hyperpolarized xenon gas
What this could lead to
If successful, MRI could become a safer, radiation-free way to detect and track lung scarring in scleroderma patients.
What could go wrong
This is a small, completed study with only 25 participants. MRI may not be as accurate as CT scans, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

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